Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              19     665
NP_005913                                                              19     665
XP_005267046                                                           19     665
XP_005267045                                                           19     665
NP_001406                                                              18    1482
NP_001010846                                                           17    3301
NP_001193976                                                           17    3301
NP_647537                                                              17    3301
NP_647538                                                              17    3301
XP_005260918                                                           17    3301
XP_005260917                                                           17    3301
NP_001014830                                                           17    4312
NP_002834                                                              16    5631
NP_653269                                                              16    5631
NP_000515                                                              16    5631
NP_006717                                                              16    5631
NP_001243040                                                           16    5631
NP_001243035                                                           16    5631
NP_004249                                                              16    5631
NP_001243038                                                           16    5631
NP_056234                                                              16    5631
NP_776169                                                              16    5631
NP_001186211                                                           16    5631
XP_005274542                                                           16    5631
XP_006718332                                                           16    5631
XP_005263433                                                           16    5631
XP_005263432                                                           16    5631
XP_005263431                                                           16    5631
XP_006714492                                                           16    5631
XP_005263430                                                           16    5631
XP_005263429                                                           16    5631
NP_005426                                                              16    7355
NP_036325                                                              16    7355
NP_001035810                                                           16    7355
NP_000393                                                              16    7355
NP_002702                                                              16    7355
NP_110398                                                              16    7355
NP_001171705                                                           16    7355
NP_001171706                                                           16    7355
NP_001171702                                                           16    7355
NP_001171703                                                           16    7355
NP_001171704                                                           16    7355
XP_006726519                                                           16    7355
XP_005274715                                                           16    7355
XP_005274714                                                           16    7355
XP_006724259                                                           16    7355
XP_005261497                                                           16    7355
XP_005261496                                                           16    7355
XP_006724258                                                           16    7355
XP_006716191                                                           16    7355
XP_006716190                                                           16    7355
XP_005250530                                                           16    7355
XP_006711954                                                           16    7355
NP_066938                                                              16    7355
NP_060906                                                              16    7355
NP_003360                                                              15    9605
NP_055951                                                              15    9605
NP_001129175                                                           15    9605
NP_038465                                                              15    9605
NP_776161                                                              15    9605
NP_036549                                                              15    9605
NP_076917                                                              15    9605
NP_858057                                                              15    9605
NP_851939                                                              15    9605
NP_077295                                                              15    9605
NP_945314                                                              15    9605
NP_005550                                                              15    9605
XP_005257273                                                           15    9605
XP_006718738                                                           15    9605
XP_006718737                                                           15    9605
XP_006718736                                                           15    9605
XP_005274266                                                           15    9605
XP_005271976                                                           15    9605
XP_005265032                                                           15    9605
XP_005265031                                                           15    9605
XP_005265030                                                           15    9605
>NP_006715
          Length = 1558

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LGYSNAKLP 9
           LG SNAKLP
Sbjct: 191 LGCSNAKLP 199
>NP_005913
          Length = 1608

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LGYSNAKLP 9
           LG SNAKLP
Sbjct: 191 LGCSNAKLP 199
>XP_005267046
          Length = 1554

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LGYSNAKLP 9
           LG SNAKLP
Sbjct: 191 LGCSNAKLP 199
>XP_005267045
          Length = 1604

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LGYSNAKLP 9
           LG SNAKLP
Sbjct: 191 LGCSNAKLP 199
>NP_001406
          Length = 472

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  LGYSNAKL 8
          LGY+NAK+
Sbjct: 81 LGYANAKI 88
>NP_001010846
          Length = 495

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   YSNAKLP 9
           YSN KLP
Sbjct: 471 YSNEKLP 477
>NP_001193976
          Length = 1156

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   YSNAKLP 9
           YSN KLP
Sbjct: 218 YSNLKLP 224
>NP_647537
          Length = 1429

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   YSNAKLP 9
           YSN KLP
Sbjct: 334 YSNLKLP 340
>NP_647538
          Length = 1272

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   YSNAKLP 9
           YSN KLP
Sbjct: 334 YSNLKLP 340
>XP_005260918
          Length = 1111

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   YSNAKLP 9
           YSN KLP
Sbjct: 334 YSNLKLP 340
>XP_005260917
          Length = 1289

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   YSNAKLP 9
           YSN KLP
Sbjct: 334 YSNLKLP 340
>NP_001014830
          Length = 324

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LGYSNAKL 8
          LG+SN+K+
Sbjct: 4  LGFSNSKM 11
>NP_002834
          Length = 1337

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LGYSNAKL 8
           LGY N KL
Sbjct: 915 LGYYNGKL 922
>NP_653269
          Length = 1149

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LGYSNAK 7
            LGY+N+K
Sbjct: 1055 LGYTNSK 1061
>NP_000515
          Length = 422

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LGYSNAKL 8
           LGYSN+ L
Sbjct: 388 LGYSNSLL 395
>NP_006717
          Length = 2863

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SNAKLP 9
            SNAKLP
Sbjct: 1773 SNAKLP 1778
>NP_001243040
          Length = 959

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GYSNAKLP 9
           GYS+ K+P
Sbjct: 505 GYSDLKVP 512
>NP_001243035
          Length = 1021

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GYSNAKLP 9
           GYS+ K+P
Sbjct: 567 GYSDLKVP 574
>NP_004249
          Length = 1021

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GYSNAKLP 9
           GYS+ K+P
Sbjct: 567 GYSDLKVP 574
>NP_001243038
          Length = 1021

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GYSNAKLP 9
           GYS+ K+P
Sbjct: 567 GYSDLKVP 574
>NP_056234
          Length = 2828

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    YSNAKLP 9
            YSN +LP
Sbjct: 1725 YSNGRLP 1731
>NP_776169
          Length = 354

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LGYSNAKLP 9
           LG +NA LP
Sbjct: 303 LGTTNASLP 311
>NP_001186211
          Length = 2851

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SNAKLP 9
            SNAKLP
Sbjct: 1773 SNAKLP 1778
>XP_005274542
          Length = 2853

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    YSNAKLP 9
            YSN +LP
Sbjct: 1750 YSNGRLP 1756
>XP_006718332
          Length = 1332

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   LGYSNAKL 8
           LGY N KL
Sbjct: 910 LGYYNGKL 917
>XP_005263433
          Length = 2832

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SNAKLP 9
            SNAKLP
Sbjct: 1737 SNAKLP 1742
>XP_005263432
          Length = 2852

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SNAKLP 9
            SNAKLP
Sbjct: 1773 SNAKLP 1778
>XP_005263431
          Length = 2857

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SNAKLP 9
            SNAKLP
Sbjct: 1773 SNAKLP 1778
>XP_006714492
          Length = 2867

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SNAKLP 9
            SNAKLP
Sbjct: 1773 SNAKLP 1778
>XP_005263430
          Length = 2868

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SNAKLP 9
            SNAKLP
Sbjct: 1773 SNAKLP 1778
>XP_005263429
          Length = 2868

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SNAKLP 9
            SNAKLP
Sbjct: 1773 SNAKLP 1778
>NP_005426
          Length = 1597

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LGYSNAKLP 9
           L YS+++LP
Sbjct: 624 LSYSHSELP 632
>NP_036325
          Length = 537

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  LGYSNAKLP 9
          LGY+  K+P
Sbjct: 56 LGYNVTKMP 64
>NP_001035810
          Length = 515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   YSNAKLP 9
           Y N KLP
Sbjct: 428 YKNVKLP 434
>NP_000393
          Length = 545

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   YSNAKLP 9
           Y N KLP
Sbjct: 458 YKNVKLP 464
>NP_002702
          Length = 1122

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3    YSNAKLP 9
            Y+N+K+P
Sbjct: 1071 YTNSKIP 1077
>NP_110398
          Length = 373

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   GYSNAKL 8
           GY+N KL
Sbjct: 295 GYANGKL 301
>NP_001171705
          Length = 949

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   YSNAKLP 9
           YSN +LP
Sbjct: 910 YSNLRLP 916
>NP_001171706
          Length = 948

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   YSNAKLP 9
           YSN +LP
Sbjct: 909 YSNLRLP 915
>NP_001171702
          Length = 1023

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   YSNAKLP 9
           YSN +LP
Sbjct: 984 YSNLRLP 990
>NP_001171703
          Length = 1013

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   YSNAKLP 9
           YSN +LP
Sbjct: 974 YSNLRLP 980
>NP_001171704
          Length = 1011

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   YSNAKLP 9
           YSN +LP
Sbjct: 972 YSNLRLP 978
>XP_006726519
          Length = 1493

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LGYSNAKLP 9
           L YS+++LP
Sbjct: 605 LSYSHSELP 613
>XP_005274715
          Length = 516

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   YSNAKLP 9
           Y N KLP
Sbjct: 429 YKNVKLP 435
>XP_005274714
          Length = 546

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   YSNAKLP 9
           Y N KLP
Sbjct: 459 YKNVKLP 465
>XP_006724259
          Length = 947

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   YSNAKLP 9
           YSN +LP
Sbjct: 908 YSNLRLP 914
>XP_005261497
          Length = 960

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   YSNAKLP 9
           YSN +LP
Sbjct: 921 YSNLRLP 927
>XP_005261496
          Length = 1012

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   YSNAKLP 9
           YSN +LP
Sbjct: 973 YSNLRLP 979
>XP_006724258
          Length = 1022

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   YSNAKLP 9
           YSN +LP
Sbjct: 983 YSNLRLP 989
>XP_006716191
          Length = 1543

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LGYSNAKLP 9
           L YS+++LP
Sbjct: 624 LSYSHSELP 632
>XP_006716190
          Length = 1597

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LGYSNAKLP 9
           L YS+++LP
Sbjct: 624 LSYSHSELP 632
>XP_005250530
          Length = 921

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   YSNAKLP 9
           Y+N+K+P
Sbjct: 870 YTNSKIP 876
>XP_006711954
          Length = 254

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LGYSNAK 7
          +G+SNAK
Sbjct: 71 VGFSNAK 77
>NP_066938
          Length = 1024

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   YSNAKLP 9
           YSN +LP
Sbjct: 985 YSNLRLP 991
>NP_060906
          Length = 391

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LGYSNAK 7
           +G+SNAK
Sbjct: 208 VGFSNAK 214
>NP_003360
          Length = 699

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GYSNAK 7
           GYSNA+
Sbjct: 170 GYSNAQ 175
>NP_055951
          Length = 2570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    LGYSNA 6
            LGY+NA
Sbjct: 2343 LGYANA 2348
>NP_001129175
          Length = 840

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LGYSNAKLP 9
           LG+++ +LP
Sbjct: 567 LGFTSVRLP 575
>NP_038465
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   LGYSNAKLP 9
           LG+++ +LP
Sbjct: 586 LGFTSVRLP 594
>NP_776161
          Length = 990

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LGYSNAKLP 9
           + Y N KLP
Sbjct: 449 INYFNPKLP 457
>NP_036549
          Length = 332

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  YSNAKLP 9
          Y N+KLP
Sbjct: 63 YLNSKLP 69
>NP_076917
          Length = 357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   LGYSNA 6
           LGYSN+
Sbjct: 326 LGYSNS 331
>NP_858057
          Length = 268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  YSNAKLP 9
          Y N+KLP
Sbjct: 63 YLNSKLP 69
>NP_851939
          Length = 222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2   GYSNAKLP 9
           GY+  K+P
Sbjct: 123 GYAEGKIP 130
>NP_077295
          Length = 263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1  LGYSNAK 7
          LGY N K
Sbjct: 82 LGYKNVK 88
>NP_945314
          Length = 1386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    LGYSNAKLP 9
            LGY  A LP
Sbjct: 1055 LGYHLASLP 1063
>NP_005550
          Length = 3075

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2    GYSNAKLP 9
            GY   KLP
Sbjct: 1379 GYHRGKLP 1386
>XP_005257273
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  YSNAKLP 9
          Y N+KLP
Sbjct: 40 YLNSKLP 46
>XP_006718738
          Length = 447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GYSNAK 7
           GYSNA+
Sbjct: 170 GYSNAQ 175
>XP_006718737
          Length = 458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GYSNAK 7
           GYSNA+
Sbjct: 170 GYSNAQ 175
>XP_006718736
          Length = 481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GYSNAK 7
           GYSNA+
Sbjct: 170 GYSNAQ 175
>XP_005274266
          Length = 552

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  GYSNAK 7
          GYSNA+
Sbjct: 23 GYSNAQ 28
>XP_005271976
          Length = 582

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  LGYSNAKLP 9
          + Y N KLP
Sbjct: 41 INYFNPKLP 49
>XP_005265032
          Length = 2545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    LGYSNA 6
            LGY+NA
Sbjct: 2293 LGYANA 2298
>XP_005265031
          Length = 2569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    LGYSNA 6
            LGY+NA
Sbjct: 2343 LGYANA 2348
>XP_005265030
          Length = 2595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    LGYSNA 6
            LGY+NA
Sbjct: 2343 LGYANA 2348
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.134    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 573,315
Number of extensions: 1018
Number of successful extensions: 76
Number of sequences better than 10000.0: 76
Number of HSP's gapped: 76
Number of HSP's successfully gapped: 76
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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