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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_997290                                                              20     509
NP_722576                                                              19     665
XP_005262424                                                           19     665
NP_588614                                                              17    2528
XP_006720235                                                           17    2528
NP_004560                                                              17    2528
NP_001121902                                                           17    3301
NP_001121901                                                           17    3301
NP_064544                                                              17    3301
NP_001241878                                                           17    3301
XP_006714339                                                           17    3301
XP_006714338                                                           17    3301
NP_001127854                                                           16    5631
NP_078966                                                              16    5631
NP_055684                                                              16    5631
XP_006723004                                                           16    5631
NP_659404                                                              16    7355
NP_001269536                                                           16    7355
NP_001157861                                                           16    7355
NP_001157860                                                           16    7355
NP_001157859                                                           16    7355
NP_001157858                                                           16    7355
NP_057424                                                              16    7355
XP_006724792                                                           16    7355
NP_004332                                                              15    9605
XP_005267654                                                           15    9605
XP_005264615                                                           15    9605
XP_006712164                                                           15    9605
XP_005264614                                                           15    9605
XP_005264613                                                           15    9605
XP_005264612                                                           15    9605

>NP_997290
          Length = 438

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   GIRMTSSN 9
           GIRMTSSN
Sbjct: 187 GIRMTSSN 194



>NP_722576
          Length = 3080

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LGIRMTSSN 9
            LG RMTSSN
Sbjct: 1866 LGTRMTSSN 1874



>XP_005262424
          Length = 2875

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LGIRMTSSN 9
            LG RMTSSN
Sbjct: 1661 LGTRMTSSN 1669



>NP_588614
          Length = 789

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LGIRMTSSN 9
           LG+RM S+N
Sbjct: 588 LGLRMNSAN 596



>XP_006720235
          Length = 184

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  LGIRMTSS 8
          LGI+MTSS
Sbjct: 92 LGIQMTSS 99



>NP_004560
          Length = 188

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LGIRMTSS 8
           LGI+MTSS
Sbjct: 96  LGIQMTSS 103



>NP_001121902
          Length = 1028

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LGIRMTSSN 9
           LGI +TS+N
Sbjct: 936 LGINLTSAN 944



>NP_001121901
          Length = 1028

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LGIRMTSSN 9
           LGI +TS+N
Sbjct: 936 LGINLTSAN 944



>NP_064544
          Length = 1026

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LGIRMTSSN 9
           LGI +TS+N
Sbjct: 934 LGINLTSAN 942



>NP_001241878
          Length = 596

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LGIRMTSSN 9
           LGI +TS+N
Sbjct: 504 LGINLTSAN 512



>XP_006714339
          Length = 795

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LGIRMTSSN 9
           LGI +TS+N
Sbjct: 703 LGINLTSAN 711



>XP_006714338
          Length = 998

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LGIRMTSSN 9
           LGI +TS+N
Sbjct: 906 LGINLTSAN 914



>NP_001127854
          Length = 1114

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GIRMTSS 8
           GIR+TSS
Sbjct: 810 GIRLTSS 816



>NP_078966
          Length = 14507

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LGIRMTSSN 9
            LG+R TSS+
Sbjct: 8121 LGLRKTSSS 8129



>NP_055684
          Length = 963

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GIRMTSS 8
           GIR+TSS
Sbjct: 824 GIRLTSS 830



>XP_006723004
          Length = 6443

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LGIRMTSSN 9
          LG+R TSS+
Sbjct: 35 LGLRKTSSS 43



>NP_659404
          Length = 547

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GIRMTSSN 9
           G RMTS+N
Sbjct: 371 GNRMTSTN 378



>NP_001269536
          Length = 535

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GIRMTSSN 9
           G RMTS+N
Sbjct: 359 GNRMTSTN 366



>NP_001157861
          Length = 1391

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    IRMTSSN 9
            +RMTS+N
Sbjct: 1051 VRMTSAN 1057



>NP_001157860
          Length = 1504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    IRMTSSN 9
            +RMTS+N
Sbjct: 1051 VRMTSAN 1057



>NP_001157859
          Length = 1509

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    IRMTSSN 9
            +RMTS+N
Sbjct: 1056 VRMTSAN 1062



>NP_001157858
          Length = 1609

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    IRMTSSN 9
            +RMTS+N
Sbjct: 1051 VRMTSAN 1057



>NP_057424
          Length = 1601

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    IRMTSSN 9
            +RMTS+N
Sbjct: 1051 VRMTSAN 1057



>XP_006724792
          Length = 411

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GIRMTSSN 9
           G RMTS+N
Sbjct: 235 GNRMTSTN 242



>NP_004332
          Length = 2225

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LGIRMTSS 8
            LG+ MTS+
Sbjct: 1278 LGVEMTST 1285



>XP_005267654
          Length = 212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GIRMTSSN 9
           G+RM +SN
Sbjct: 179 GLRMRASN 186



>XP_005264615
          Length = 2162

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LGIRMTSS 8
            LG+ MTS+
Sbjct: 1215 LGVEMTST 1222



>XP_006712164
          Length = 2179

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LGIRMTSS 8
            LG+ MTS+
Sbjct: 1215 LGVEMTST 1222



>XP_005264614
          Length = 2191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LGIRMTSS 8
            LG+ MTS+
Sbjct: 1278 LGVEMTST 1285



>XP_005264613
          Length = 2208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LGIRMTSS 8
            LG+ MTS+
Sbjct: 1278 LGVEMTST 1285



>XP_005264612
          Length = 2242

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    LGIRMTSS 8
            LG+ MTS+
Sbjct: 1278 LGVEMTST 1285



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.125    0.317 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 311,990
Number of extensions: 341
Number of successful extensions: 31
Number of sequences better than 10000.0: 31
Number of HSP's gapped: 31
Number of HSP's successfully gapped: 31
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)