Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     665
NP_671714                                                              19     665
XP_006715890                                                           19     665
XP_005250160                                                           19     665
XP_005250159                                                           19     665
NP_001159743                                                           18    1482
NP_001273721                                                           18    1482
NP_001273723                                                           18    1482
NP_001273724                                                           18    1482
NP_001273722                                                           18    1482
NP_694568                                                              18    1482
NP_001166951                                                           17    3301
NP_001166950                                                           17    3301
NP_056000                                                              17    3301
NP_075463                                                              17    3301
XP_005262309                                                           17    3301
XP_005262308                                                           17    3301
XP_006724700                                                           17    3301
XP_005262307                                                           17    3301
XP_006724699                                                           17    3301
XP_005262306                                                           17    3301
XP_006723934                                                           17    3301
XP_006719812                                                           17    3301
NP_001077083                                                           17    4312
NP_619520                                                              17    4312
NP_055781                                                              17    4312
NP_056127                                                              17    4312
XP_006721083                                                           17    4312
XP_006714407                                                           17    4312
XP_006714406                                                           17    4312
XP_006714405                                                           17    4312
XP_005263349                                                           17    4312
XP_005263348                                                           17    4312
XP_005263347                                                           17    4312
XP_005263346                                                           17    4312
XP_005263345                                                           17    4312
XP_005263344                                                           17    4312
XP_005263343                                                           17    4312
XP_005263342                                                           17    4312
XP_005263341                                                           17    4312
XP_005263340                                                           17    4312
XP_005263339                                                           17    4312
XP_006713096                                                           17    4312
XP_006713095                                                           17    4312
NP_078858                                                              16    5631
NP_001278232                                                           16    5631
NP_001278214                                                           16    5631
NP_001121132                                                           16    7355
NP_055689                                                              16    7355
NP_940912                                                              16    7355
XP_005263605                                                           16    7355
XP_005263604                                                           16    7355
XP_005263602                                                           16    7355
XP_005263600                                                           16    7355
NP_057297                                                              15    9605
NP_060773                                                              15    9605
NP_689856                                                              15    9605
NP_596870                                                              15    9605
XP_006723329                                                           15    9605
XP_005259110                                                           15    9605
XP_005259109                                                           15    9605
XP_005257435                                                           15    9605
XP_006721972                                                           15    9605
XP_005257434                                                           15    9605
XP_005257433                                                           15    9605
XP_005254846                                                           15    9605
XP_006720615                                                           15    9605
XP_006715205                                                           15    9605
XP_006715204                                                           15    9605
NP_002392                                                              15    9605
NP_976226                                                              15    9605
NP_060378                                                              15    9605
>NP_005742
          Length = 3907

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LGILDRSSE 9
            LGILDRSS+
Sbjct: 1754 LGILDRSSK 1762
>NP_671714
          Length = 3899

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LGILDRSSE 9
            LGILDRSS+
Sbjct: 1754 LGILDRSSK 1762
>XP_006715890
          Length = 3860

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LGILDRSSE 9
            LGILDRSS+
Sbjct: 1707 LGILDRSSK 1715
>XP_005250160
          Length = 3939

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LGILDRSSE 9
            LGILDRSS+
Sbjct: 1786 LGILDRSSK 1794
>XP_005250159
          Length = 3952

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LGILDRSSE 9
            LGILDRSS+
Sbjct: 1786 LGILDRSSK 1794
>NP_001159743
          Length = 1277

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LGILDRSSE 9
            L ILDRSSE
Sbjct: 1072 LDILDRSSE 1080
>NP_001273721
          Length = 1339

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LGILDRSSE 9
            L ILDRSSE
Sbjct: 1134 LDILDRSSE 1142
>NP_001273723
          Length = 596

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LGILDRSSE 9
           L ILDRSSE
Sbjct: 391 LDILDRSSE 399
>NP_001273724
          Length = 574

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LGILDRSSE 9
           L ILDRSSE
Sbjct: 369 LDILDRSSE 377
>NP_001273722
          Length = 512

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LGILDRSSE 9
           L ILDRSSE
Sbjct: 307 LDILDRSSE 315
>NP_694568
          Length = 652

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LGILDRSSE 9
           L ILDRSSE
Sbjct: 447 LDILDRSSE 455
>NP_001166951
          Length = 414

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   ILDRSSE 9
           ILDRSSE
Sbjct: 210 ILDRSSE 216
>NP_001166950
          Length = 463

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   ILDRSSE 9
           ILDRSSE
Sbjct: 259 ILDRSSE 265
>NP_056000
          Length = 516

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   ILDRSSE 9
           ILDRSSE
Sbjct: 312 ILDRSSE 318
>NP_075463
          Length = 3013

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    GILDRSSE 9
            G++DRSS+
Sbjct: 1989 GVIDRSSD 1996
>XP_005262309
          Length = 495

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   ILDRSSE 9
           ILDRSSE
Sbjct: 291 ILDRSSE 297
>XP_005262308
          Length = 495

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   ILDRSSE 9
           ILDRSSE
Sbjct: 291 ILDRSSE 297
>XP_006724700
          Length = 495

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   ILDRSSE 9
           ILDRSSE
Sbjct: 291 ILDRSSE 297
>XP_005262307
          Length = 495

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   ILDRSSE 9
           ILDRSSE
Sbjct: 291 ILDRSSE 297
>XP_006724699
          Length = 521

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   ILDRSSE 9
           ILDRSSE
Sbjct: 317 ILDRSSE 323
>XP_005262306
          Length = 523

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   ILDRSSE 9
           ILDRSSE
Sbjct: 319 ILDRSSE 325
>XP_006723934
          Length = 419

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  GILDRSSE 9
          GI+DRS E
Sbjct: 15 GIMDRSKE 22
>XP_006719812
          Length = 3019

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    GILDRSSE 9
            G++DRSS+
Sbjct: 1986 GVIDRSSD 1993
>NP_001077083
          Length = 523

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LGILDRSS 8
           LG+L+RSS
Sbjct: 450 LGLLERSS 457
>NP_619520
          Length = 1194

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LGILDRSSE 9
           LG++DR++E
Sbjct: 315 LGLVDRNNE 323
>NP_055781
          Length = 1155

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LGILDRSSE 9
           LG++DR++E
Sbjct: 276 LGLVDRNNE 284
>NP_056127
          Length = 5005

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    GILDRSSE 9
            GIL++SSE
Sbjct: 2721 GILEKSSE 2728
>XP_006721083
          Length = 534

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LGILDRSS 8
           LG+L+RSS
Sbjct: 450 LGLLERSS 457
>XP_006714407
          Length = 5004

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    GILDRSSE 9
            GIL++SSE
Sbjct: 2720 GILEKSSE 2727
>XP_006714406
          Length = 3680

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    GILDRSSE 9
            GIL++SSE
Sbjct: 2721 GILEKSSE 2728
>XP_006714405
          Length = 4103

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    GILDRSSE 9
            GIL++SSE
Sbjct: 1798 GILEKSSE 1805
>XP_005263349
          Length = 4410

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    GILDRSSE 9
            GIL++SSE
Sbjct: 2105 GILEKSSE 2112
>XP_005263348
          Length = 4443

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    GILDRSSE 9
            GIL++SSE
Sbjct: 2138 GILEKSSE 2145
>XP_005263347
          Length = 4640

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    GILDRSSE 9
            GIL++SSE
Sbjct: 2721 GILEKSSE 2728
>XP_005263346
          Length = 4983

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    GILDRSSE 9
            GIL++SSE
Sbjct: 2678 GILEKSSE 2685
>XP_005263345
          Length = 4991

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    GILDRSSE 9
            GIL++SSE
Sbjct: 2721 GILEKSSE 2728
>XP_005263344
          Length = 5005

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    GILDRSSE 9
            GIL++SSE
Sbjct: 2721 GILEKSSE 2728
>XP_005263343
          Length = 5009

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    GILDRSSE 9
            GIL++SSE
Sbjct: 2721 GILEKSSE 2728
>XP_005263342
          Length = 5025

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    GILDRSSE 9
            GIL++SSE
Sbjct: 2720 GILEKSSE 2727
>XP_005263341
          Length = 5026

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    GILDRSSE 9
            GIL++SSE
Sbjct: 2721 GILEKSSE 2728
>XP_005263340
          Length = 5026

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    GILDRSSE 9
            GIL++SSE
Sbjct: 2721 GILEKSSE 2728
>XP_005263339
          Length = 5026

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    GILDRSSE 9
            GIL++SSE
Sbjct: 2721 GILEKSSE 2728
>XP_006713096
          Length = 1162

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LGILDRSSE 9
           LG++DR++E
Sbjct: 283 LGLVDRNNE 291
>XP_006713095
          Length = 1222

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LGILDRSSE 9
           LG++DR++E
Sbjct: 343 LGLVDRNNE 351
>NP_078858
          Length = 4981

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    GILDRSSE 9
            GILDR  E
Sbjct: 3359 GILDREKE 3366
>NP_001278232
          Length = 4983

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    GILDRSSE 9
            GILDR  E
Sbjct: 3361 GILDREKE 3368
>NP_001278214
          Length = 4982

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    GILDRSSE 9
            GILDR  E
Sbjct: 3361 GILDREKE 3368
>NP_001121132
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LGILDRS 7
           LG++DRS
Sbjct: 289 LGVVDRS 295
>NP_055689
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LGILDRS 7
           LG++DRS
Sbjct: 289 LGVVDRS 295
>NP_940912
          Length = 1313

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LGILDRSSE 9
           +GI DR SE
Sbjct: 120 VGIRDRESE 128
>XP_005263605
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LGILDRS 7
           LG++DRS
Sbjct: 289 LGVVDRS 295
>XP_005263604
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LGILDRS 7
           LG++DRS
Sbjct: 289 LGVVDRS 295
>XP_005263602
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LGILDRS 7
           LG++DRS
Sbjct: 289 LGVVDRS 295
>XP_005263600
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LGILDRS 7
           LG++DRS
Sbjct: 289 LGVVDRS 295
>NP_057297
          Length = 581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LDRSSE 9
           LDRSSE
Sbjct: 368 LDRSSE 373
>NP_060773
          Length = 924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LGILDRSS 8
           +GILD+S+
Sbjct: 98  IGILDQSA 105
>NP_689856
          Length = 1749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    LGILDRSS 8
            LG++D+S+
Sbjct: 1498 LGVMDKST 1505
>NP_596870
          Length = 5604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    LGILDRSSE 9
            L +LD SSE
Sbjct: 3718 LSLLDTSSE 3726
>XP_006723329
          Length = 304

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GILDRSSE 9
           G+LDRS +
Sbjct: 213 GLLDRSQK 220
>XP_005259110
          Length = 411

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GILDRSSE 9
           G+LDRS +
Sbjct: 213 GLLDRSQK 220
>XP_005259109
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GILDRSSE 9
           G+LDRS +
Sbjct: 213 GLLDRSQK 220
>XP_005257435
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LGILDRSS 8
           + ILDRSS
Sbjct: 135 IDILDRSS 142
>XP_006721972
          Length = 541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LGILDRSS 8
          + ILDRSS
Sbjct: 19 IDILDRSS 26
>XP_005257434
          Length = 622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LGILDRSS 8
           + ILDRSS
Sbjct: 104 IDILDRSS 111
>XP_005257433
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LGILDRSS 8
           + ILDRSS
Sbjct: 135 IDILDRSS 142
>XP_005254846
          Length = 351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LDRSSE 9
           LDRSSE
Sbjct: 138 LDRSSE 143
>XP_006720615
          Length = 448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  LGILDRSS 8
          LG+LD+ S
Sbjct: 17 LGVLDKRS 24
>XP_006715205
          Length = 924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LGILDRSS 8
           +GILD+S+
Sbjct: 98  IGILDQSA 105
>XP_006715204
          Length = 924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LGILDRSS 8
           +GILD+S+
Sbjct: 98  IGILDQSA 105
>NP_002392
          Length = 626

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LGILDRSS 8
           + ILDRSS
Sbjct: 104 IDILDRSS 111
>NP_976226
          Length = 657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LGILDRSS 8
           + ILDRSS
Sbjct: 135 IDILDRSS 142
>NP_060378
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GILDRSSE 9
           G+LDRS +
Sbjct: 213 GLLDRSQK 220
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.311    0.137    0.344 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 458,716
Number of extensions: 601
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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