Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              18    1935
XP_006718908                                                           18    1935
XP_005271621                                                           18    1935
XP_006718907                                                           18    1935
XP_006718906                                                           18    1935
XP_005271619                                                           18    1935
XP_005271618                                                           18    1935
NP_004685                                                              17    3301
NP_001167637                                                           17    3301
XP_006722232                                                           17    3301
XP_005257846                                                           17    3301
NP_076409                                                              17    4312
NP_001165402                                                           16    5631
NP_001165401                                                           16    5631
NP_071407                                                              16    5631
NP_775760                                                              16    5631
XP_006718005                                                           16    5631
XP_006718004                                                           16    5631
XP_006718003                                                           16    5631
XP_005275746                                                           16    5631
XP_003403671                                                           16    5631
XP_006710003                                                           16    5631
NP_653267                                                              16    7355
NP_002636                                                              16    7355
XP_005253037                                                           16    7355
XP_005253036                                                           16    7355
XP_005253035                                                           16    7355
XP_005253034                                                           16    7355
NP_001153844                                                           15    9605
NP_113654                                                              15    9605
NP_065944                                                              15    9605
NP_001138462                                                           15    9605
NP_002971                                                              15    9605
NP_060249                                                              15    9605
XP_006716727                                                           15    9605
XP_005251134                                                           15    9605
XP_005263787                                                           15    9605
XP_006712747                                                           15    9605
XP_006712746                                                           15    9605
>NP_000042
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LFVNLLQLS 9
            L VNLLQLS
Sbjct: 1647 LVVNLLQLS 1655
>XP_006718908
          Length = 1708

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LFVNLLQLS 9
           L VNLLQLS
Sbjct: 299 LVVNLLQLS 307
>XP_005271621
          Length = 2708

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LFVNLLQLS 9
            L VNLLQLS
Sbjct: 1299 LVVNLLQLS 1307
>XP_006718907
          Length = 3050

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LFVNLLQLS 9
            L VNLLQLS
Sbjct: 1641 LVVNLLQLS 1649
>XP_006718906
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LFVNLLQLS 9
            L VNLLQLS
Sbjct: 1647 LVVNLLQLS 1655
>XP_005271619
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LFVNLLQLS 9
            L VNLLQLS
Sbjct: 1647 LVVNLLQLS 1655
>XP_005271618
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LFVNLLQLS 9
            L VNLLQLS
Sbjct: 1647 LVVNLLQLS 1655
>NP_004685
          Length = 523

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LFVNLLQLS 9
           LFV LLQL+
Sbjct: 184 LFVGLLQLN 192
>NP_001167637
          Length = 523

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LFVNLLQLS 9
           LFV LLQL+
Sbjct: 184 LFVGLLQLN 192
>XP_006722232
          Length = 523

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LFVNLLQLS 9
           LFV LLQL+
Sbjct: 184 LFVGLLQLN 192
>XP_005257846
          Length = 523

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LFVNLLQLS 9
           LFV LLQL+
Sbjct: 184 LFVGLLQLN 192
>NP_076409
          Length = 303

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LFVNLLQLS 9
           LF+NL+Q++
Sbjct: 141 LFLNLIQIN 149
>NP_001165402
          Length = 1061

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LFVNLLQLS 9
           +FVNLL L+
Sbjct: 876 VFVNLLDLN 884
>NP_001165401
          Length = 1381

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LFVNLLQLS 9
           +FVNLL L+
Sbjct: 876 VFVNLLDLN 884
>NP_071407
          Length = 3354

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LFVNLLQLS 9
           +FVNLL L+
Sbjct: 876 VFVNLLDLN 884
>NP_775760
          Length = 1585

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LFVNLLQ 7
           +F+NLLQ
Sbjct: 276 IFINLLQ 282
>XP_006718005
          Length = 3397

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LFVNLLQLS 9
           +FVNLL L+
Sbjct: 919 VFVNLLDLN 927
>XP_006718004
          Length = 3399

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LFVNLLQLS 9
           +FVNLL L+
Sbjct: 921 VFVNLLDLN 929
>XP_006718003
          Length = 3419

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LFVNLLQLS 9
           +FVNLL L+
Sbjct: 941 VFVNLLDLN 949
>XP_005275746
          Length = 3352

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LFVNLLQLS 9
           +FVNLL L+
Sbjct: 874 VFVNLLDLN 882
>XP_003403671
          Length = 3354

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LFVNLLQLS 9
           +FVNLL L+
Sbjct: 876 VFVNLLDLN 884
>XP_006710003
          Length = 3374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LFVNLLQLS 9
           +FVNLL L+
Sbjct: 896 VFVNLLDLN 904
>NP_653267
          Length = 4753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LFVNLLQLS 9
            LF+ LLQL+
Sbjct: 3029 LFLRLLQLA 3037
>NP_002636
          Length = 1686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LFVNLLQL 8
            LF+NLL L
Sbjct: 1329 LFLNLLSL 1336
>XP_005253037
          Length = 1306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LFVNLLQL 8
           LF+NLL L
Sbjct: 949 LFLNLLSL 956
>XP_005253036
          Length = 1686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LFVNLLQL 8
            LF+NLL L
Sbjct: 1329 LFLNLLSL 1336
>XP_005253035
          Length = 1686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LFVNLLQL 8
            LF+NLL L
Sbjct: 1329 LFLNLLSL 1336
>XP_005253034
          Length = 1686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LFVNLLQL 8
            LF+NLL L
Sbjct: 1329 LFLNLLSL 1336
>NP_001153844
          Length = 1148

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LFVNLLQLS 9
           +++NL QLS
Sbjct: 372 VYINLRQLS 380
>NP_113654
          Length = 1246

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LFVNLLQLS 9
           +++NL QLS
Sbjct: 470 VYINLRQLS 478
>NP_065944
          Length = 1701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LFVNLLQ 7
           LFVNL++
Sbjct: 325 LFVNLME 331
>NP_001138462
          Length = 1742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LFVNLLQLS 9
           LF+NLL  S
Sbjct: 495 LFINLLNES 503
>NP_002971
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   LFVNLLQL 8
           LF+N+L++
Sbjct: 312 LFINILRI 319
>NP_060249
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LFVNLLQL 8
           LFVN+L L
Sbjct: 298 LFVNILGL 305
>XP_006716727
          Length = 1139

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LFVNLLQLS 9
           +++NL QLS
Sbjct: 363 VYINLRQLS 371
>XP_005251134
          Length = 1148

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LFVNLLQLS 9
           +++NL QLS
Sbjct: 372 VYINLRQLS 380
>XP_005263787
          Length = 262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   LFVNLLQL 8
           LF+N+L++
Sbjct: 134 LFINILRI 141
>XP_006712747
          Length = 290

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   LFVNLLQL 8
           LF+N+L++
Sbjct: 157 LFINILRI 164
>XP_006712746
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   LFVNLLQL 8
           LF+N+L++
Sbjct: 312 LFINILRI 319
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.338    0.152    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 364,580
Number of extensions: 526
Number of successful extensions: 39
Number of sequences better than 10000.0: 39
Number of HSP's gapped: 39
Number of HSP's successfully gapped: 39
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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