Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              17    2528
XP_006714104                                                           17    2528
XP_005265800                                                           17    2528
XP_006714103                                                           17    2528
XP_006714102                                                           17    2528
NP_001032961                                                           17    3301
NP_057400                                                              17    3301
XP_006712656                                                           17    3301
XP_005264025                                                           17    3301
XP_006712655                                                           17    3301
NP_006729                                                              16    5631
NP_001257475                                                           16    5631
NP_009131                                                              16    5631
NP_055833                                                              16    5631
NP_001186871                                                           16    5631
XP_005254913                                                           16    5631
XP_005254912                                                           16    5631
XP_005254911                                                           16    5631
XP_005254910                                                           16    5631
XP_005254909                                                           16    5631
XP_005254908                                                           16    5631
XP_005254907                                                           16    5631
XP_005254906                                                           16    5631
XP_005254905                                                           16    5631
XP_005254904                                                           16    5631
XP_005254903                                                           16    5631
XP_005254902                                                           16    5631
XP_005254901                                                           16    5631
XP_005254900                                                           16    5631
XP_005254899                                                           16    5631
XP_005254898                                                           16    5631
XP_005254897                                                           16    5631
XP_006720441                                                           16    5631
XP_006720440                                                           16    5631
XP_006720439                                                           16    5631
XP_005254896                                                           16    5631
XP_006715464                                                           16    5631
XP_006715463                                                           16    5631
XP_006715462                                                           16    5631
XP_006715461                                                           16    5631
XP_006715460                                                           16    5631
XP_006715459                                                           16    5631
XP_006715458                                                           16    5631
XP_006715457                                                           16    5631
XP_006715456                                                           16    5631
NP_064522                                                              16    7355
XP_005272685                                                           16    7355
>NP_006197
          Length = 1089

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  LEVSSASA 8
          LEVSSASA
Sbjct: 85 LEVSSASA 92
>XP_006714104
          Length = 832

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LEVSSASA 8
           LEVSSASA
Sbjct: 110 LEVSSASA 117
>XP_005265800
          Length = 1089

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  LEVSSASA 8
          LEVSSASA
Sbjct: 85 LEVSSASA 92
>XP_006714103
          Length = 1111

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LEVSSASA 8
           LEVSSASA
Sbjct: 107 LEVSSASA 114
>XP_006714102
          Length = 1114

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LEVSSASA 8
           LEVSSASA
Sbjct: 110 LEVSSASA 117
>NP_001032961
          Length = 1250

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LEVSSASAT 9
           LE+SSAS T
Sbjct: 878 LEISSASRT 886
>NP_057400
          Length = 1251

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LEVSSASAT 9
           LE+SSAS T
Sbjct: 879 LEISSASRT 887
>XP_006712656
          Length = 761

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LEVSSASAT 9
           LE+SSAS T
Sbjct: 389 LEISSASRT 397
>XP_005264025
          Length = 1181

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LEVSSASAT 9
           LE+SSAS T
Sbjct: 809 LEISSASRT 817
>XP_006712655
          Length = 1251

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LEVSSASAT 9
           LE+SSAS T
Sbjct: 879 LEISSASRT 887
>NP_006729
          Length = 2817

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    LEVSSASA 8
            LEVSSA+A
Sbjct: 1624 LEVSSANA 1631
>NP_001257475
          Length = 1434

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LEVSSASA 8
           LEVSSA+A
Sbjct: 242 LEVSSANA 249
>NP_009131
          Length = 2813

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    LEVSSASA 8
            LEVSSA+A
Sbjct: 1620 LEVSSANA 1627
>NP_055833
          Length = 2465

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LEVSSASAT 9
            LEV SAS T
Sbjct: 1164 LEVESASVT 1172
>NP_001186871
          Length = 2476

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LEVSSASAT 9
            LEV SAS T
Sbjct: 1155 LEVESASVT 1163
>XP_005254913
          Length = 1441

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LEVSSASA 8
           LEVSSA+A
Sbjct: 242 LEVSSANA 249
>XP_005254912
          Length = 1442

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LEVSSASA 8
           LEVSSA+A
Sbjct: 242 LEVSSANA 249
>XP_005254911
          Length = 1473

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LEVSSASA 8
           LEVSSA+A
Sbjct: 273 LEVSSANA 280
>XP_005254910
          Length = 1523

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LEVSSASA 8
           LEVSSA+A
Sbjct: 282 LEVSSANA 289
>XP_005254909
          Length = 1536

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LEVSSASA 8
           LEVSSA+A
Sbjct: 295 LEVSSANA 302
>XP_005254908
          Length = 1536

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   LEVSSASA 8
           LEVSSA+A
Sbjct: 295 LEVSSANA 302
>XP_005254907
          Length = 2590

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    LEVSSASA 8
            LEVSSA+A
Sbjct: 1349 LEVSSANA 1356
>XP_005254906
          Length = 2675

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    LEVSSASA 8
            LEVSSA+A
Sbjct: 1434 LEVSSANA 1441
>XP_005254905
          Length = 2793

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    LEVSSASA 8
            LEVSSA+A
Sbjct: 1602 LEVSSANA 1609
>XP_005254904
          Length = 2802

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    LEVSSASA 8
            LEVSSA+A
Sbjct: 1602 LEVSSANA 1609
>XP_005254903
          Length = 2820

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    LEVSSASA 8
            LEVSSA+A
Sbjct: 1620 LEVSSANA 1627
>XP_005254902
          Length = 2835

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    LEVSSASA 8
            LEVSSA+A
Sbjct: 1642 LEVSSANA 1649
>XP_005254901
          Length = 2842

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    LEVSSASA 8
            LEVSSA+A
Sbjct: 1642 LEVSSANA 1649
>XP_005254900
          Length = 2843

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    LEVSSASA 8
            LEVSSA+A
Sbjct: 1602 LEVSSANA 1609
>XP_005254899
          Length = 2861

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    LEVSSASA 8
            LEVSSA+A
Sbjct: 1620 LEVSSANA 1627
>XP_005254898
          Length = 2874

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    LEVSSASA 8
            LEVSSA+A
Sbjct: 1642 LEVSSANA 1649
>XP_005254897
          Length = 2876

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    LEVSSASA 8
            LEVSSA+A
Sbjct: 1642 LEVSSANA 1649
>XP_006720441
          Length = 2881

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    LEVSSASA 8
            LEVSSA+A
Sbjct: 1642 LEVSSANA 1649
>XP_006720440
          Length = 2882

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    LEVSSASA 8
            LEVSSA+A
Sbjct: 1642 LEVSSANA 1649
>XP_006720439
          Length = 2882

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    LEVSSASA 8
            LEVSSA+A
Sbjct: 1642 LEVSSANA 1649
>XP_005254896
          Length = 2883

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    LEVSSASA 8
            LEVSSA+A
Sbjct: 1642 LEVSSANA 1649
>XP_006715464
          Length = 2027

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LEVSSASAT 9
            LEV SAS T
Sbjct: 1164 LEVESASVT 1172
>XP_006715463
          Length = 2434

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LEVSSASAT 9
            LEV SAS T
Sbjct: 1164 LEVESASVT 1172
>XP_006715462
          Length = 2452

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LEVSSASAT 9
            LEV SAS T
Sbjct: 1131 LEVESASVT 1139
>XP_006715461
          Length = 2456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LEVSSASAT 9
            LEV SAS T
Sbjct: 1155 LEVESASVT 1163
>XP_006715460
          Length = 2465

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LEVSSASAT 9
            LEV SAS T
Sbjct: 1164 LEVESASVT 1172
>XP_006715459
          Length = 2475

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LEVSSASAT 9
            LEV SAS T
Sbjct: 1154 LEVESASVT 1162
>XP_006715458
          Length = 2476

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LEVSSASAT 9
            LEV SAS T
Sbjct: 1155 LEVESASVT 1163
>XP_006715457
          Length = 2485

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LEVSSASAT 9
            LEV SAS T
Sbjct: 1164 LEVESASVT 1172
>XP_006715456
          Length = 2485

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    LEVSSASAT 9
            LEV SAS T
Sbjct: 1164 LEVESASVT 1172
>NP_064522
          Length = 841

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   LEVSSAS 7
           LEVSSAS
Sbjct: 732 LEVSSAS 738
>XP_005272685
          Length = 815

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   LEVSSAS 7
           LEVSSAS
Sbjct: 706 LEVSSAS 712
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.280   0.0912    0.183 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 203,863
Number of extensions: 145
Number of successful extensions: 47
Number of sequences better than 10000.0: 47
Number of HSP's gapped: 47
Number of HSP's successfully gapped: 47
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)

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