Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

• Home Page
• Cancer-specific
• Epitope Search
• Data Retrieval
• Browse Gene
• Browse Tissue
• Sequence Similarity
• Partially Personalized
• Submit a Protein
• Vaccine Target
• Proteome Data
• NGS data
• BLAST & Predict
• Fully Personalized
• Proteins Pair
• Proteome Pair
• Advanced Tools
• Epitope Mapping
• Cross Reactivity
• Important Information
• Acknowledgement
• Algorithm
• Help
• Developers
• Contact

Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1135
NP_055459                                                              18    1135
XP_006726410                                                           18    1135
XP_006711719                                                           18    1135
XP_006711716                                                           18    1135
XP_005273038                                                           18    1135
XP_006711164                                                           18    1135
NP_078951                                                              16    5631
NP_848604                                                              16    5631
XP_005257244                                                           16    5631
NP_892006                                                              15    9605
NP_149062                                                              15    9605
NP_056503                                                              15    9605
XP_006715488                                                           15    9605
XP_006715487                                                           15    9605
XP_006715486                                                           15    9605
XP_006715485                                                           15    9605
XP_006715484                                                           15    9605
XP_006715483                                                           15    9605
XP_006715482                                                           15    9605
XP_006715481                                                           15    9605
XP_006715480                                                           15    9605
XP_006715479                                                           15    9605
XP_006715478                                                           15    9605
XP_006715477                                                           15    9605
XP_006715476                                                           15    9605
XP_006715475                                                           15    9605
XP_006715474                                                           15    9605
XP_006715473                                                           15    9605
XP_006715472                                                           15    9605
XP_006715471                                                           15    9605
XP_006715470                                                           15    9605

>NP_001185761
          Length = 2240

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LEVKSVRAL 9
            LEVKS+RAL
Sbjct: 2226 LEVKSLRAL 2234



>NP_055459
          Length = 2346

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LEVKSVRAL 9
            LEVKS+RAL
Sbjct: 2332 LEVKSLRAL 2340



>XP_006726410
          Length = 2087

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LEVKSVRAL 9
            LEVKS+RAL
Sbjct: 2073 LEVKSLRAL 2081



>XP_006711719
          Length = 2302

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LEVKSVRAL 9
            LEVKS+RAL
Sbjct: 2288 LEVKSLRAL 2296



>XP_006711716
          Length = 2411

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LEVKSVRAL 9
            LEVKS+RAL
Sbjct: 2397 LEVKSLRAL 2405



>XP_005273038
          Length = 2509

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LEVKSVRAL 9
            LEVKS+RAL
Sbjct: 2495 LEVKSLRAL 2503



>XP_006711164
          Length = 2087

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LEVKSVRAL 9
            LEVKS+RAL
Sbjct: 2073 LEVKSLRAL 2081



>NP_078951
          Length = 1186

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LEVKSVRAL 9
           LE++ +RAL
Sbjct: 939 LEIREIRAL 947



>NP_848604
          Length = 553

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   VKSVRAL 9
           VKSVRAL
Sbjct: 486 VKSVRAL 492



>XP_005257244
          Length = 555

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   VKSVRAL 9
           VKSVRAL
Sbjct: 488 VKSVRAL 494



>NP_892006
          Length = 8797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEVKSVRAL 9
           +EV+SVR++
Sbjct: 599 VEVRSVRSM 607



>NP_149062
          Length = 8749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEVKSVRAL 9
           +EV+SVR++
Sbjct: 606 VEVRSVRSM 614



>NP_056503
          Length = 1060

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LEVKSVRA 8
           +E+KSVR+
Sbjct: 441 VEIKSVRS 448



>XP_006715488
          Length = 8721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEVKSVRAL 9
           +EV+SVR++
Sbjct: 606 VEVRSVRSM 614



>XP_006715487
          Length = 8744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEVKSVRAL 9
           +EV+SVR++
Sbjct: 606 VEVRSVRSM 614



>XP_006715486
          Length = 8758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEVKSVRAL 9
           +EV+SVR++
Sbjct: 606 VEVRSVRSM 614



>XP_006715485
          Length = 8793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEVKSVRAL 9
           +EV+SVR++
Sbjct: 606 VEVRSVRSM 614



>XP_006715484
          Length = 8794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEVKSVRAL 9
           +EV+SVR++
Sbjct: 606 VEVRSVRSM 614



>XP_006715483
          Length = 8795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEVKSVRAL 9
           +EV+SVR++
Sbjct: 606 VEVRSVRSM 614



>XP_006715482
          Length = 8797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEVKSVRAL 9
           +EV+SVR++
Sbjct: 599 VEVRSVRSM 607



>XP_006715481
          Length = 8799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEVKSVRAL 9
           +EV+SVR++
Sbjct: 559 VEVRSVRSM 567



>XP_006715480
          Length = 8799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEVKSVRAL 9
           +EV+SVR++
Sbjct: 606 VEVRSVRSM 614



>XP_006715479
          Length = 8804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEVKSVRAL 9
           +EV+SVR++
Sbjct: 606 VEVRSVRSM 614



>XP_006715478
          Length = 8809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEVKSVRAL 9
           +EV+SVR++
Sbjct: 606 VEVRSVRSM 614



>XP_006715477
          Length = 8822

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEVKSVRAL 9
           +EV+SVR++
Sbjct: 582 VEVRSVRSM 590



>XP_006715476
          Length = 8823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEVKSVRAL 9
           +EV+SVR++
Sbjct: 606 VEVRSVRSM 614



>XP_006715475
          Length = 8827

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEVKSVRAL 9
           +EV+SVR++
Sbjct: 606 VEVRSVRSM 614



>XP_006715474
          Length = 8829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEVKSVRAL 9
           +EV+SVR++
Sbjct: 589 VEVRSVRSM 597



>XP_006715473
          Length = 8832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEVKSVRAL 9
           +EV+SVR++
Sbjct: 606 VEVRSVRSM 614



>XP_006715472
          Length = 8839

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEVKSVRAL 9
           +EV+SVR++
Sbjct: 599 VEVRSVRSM 607



>XP_006715471
          Length = 8842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEVKSVRAL 9
           +EV+SVR++
Sbjct: 606 VEVRSVRSM 614



>XP_006715470
          Length = 8846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   LEVKSVRAL 9
           +EV+SVR++
Sbjct: 606 VEVRSVRSM 614



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.131    0.297 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 216,437
Number of extensions: 287
Number of successful extensions: 32
Number of sequences better than 10000.0: 32
Number of HSP's gapped: 32
Number of HSP's successfully gapped: 32
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)