Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001091068                                                           17    3301
NP_079522                                                              17    3301
XP_006713837                                                           17    3301
XP_006713836                                                           17    3301
NP_001091069                                                           17    3301
NP_055064                                                              16    7355
NP_000531                                                              15    9605
NP_001036188                                                           15    9605
NP_001273130                                                           15    9605
NP_079006                                                              15    9605
XP_006723382                                                           15    9605
XP_006723381                                                           15    9605
XP_006723380                                                           15    9605
XP_006719215                                                           15    9605
>NP_001091068
          Length = 412

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LEMLFIRS 8
           LE++FIRS
Sbjct: 134 LELIFIRS 141
>NP_079522
          Length = 412

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LEMLFIRS 8
           LE++FIRS
Sbjct: 134 LELIFIRS 141
>XP_006713837
          Length = 412

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LEMLFIRS 8
           LE++FIRS
Sbjct: 134 LELIFIRS 141
>XP_006713836
          Length = 412

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LEMLFIRS 8
           LE++FIRS
Sbjct: 134 LELIFIRS 141
>NP_001091069
          Length = 412

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LEMLFIRS 8
           LE++FIRS
Sbjct: 134 LELIFIRS 141
>NP_055064
          Length = 410

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   LEMLFIRST 9
           +E+LF R T
Sbjct: 386 IELLFFRKT 394
>NP_000531
          Length = 5038

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LEMLFIR 7
            +EMLF+R
Sbjct: 1283 VEMLFLR 1289
>NP_001036188
          Length = 5033

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LEMLFIR 7
            +EMLF+R
Sbjct: 1283 VEMLFLR 1289
>NP_001273130
          Length = 204

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LEMLFIR 7
           +EM+FIR
Sbjct: 160 VEMMFIR 166
>NP_079006
          Length = 205

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LEMLFIR 7
           +EM+FIR
Sbjct: 161 VEMMFIR 167
>XP_006723382
          Length = 5027

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LEMLFIR 7
            +EMLF+R
Sbjct: 1283 VEMLFLR 1289
>XP_006723381
          Length = 5031

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LEMLFIR 7
            +EMLF+R
Sbjct: 1282 VEMLFLR 1288
>XP_006723380
          Length = 5032

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    LEMLFIR 7
            +EMLF+R
Sbjct: 1283 VEMLFLR 1289
>XP_006719215
          Length = 205

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   LEMLFIR 7
           +EM+FIR
Sbjct: 161 VEMMFIR 167
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.341    0.147    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 334,624
Number of extensions: 330
Number of successful extensions: 14
Number of sequences better than 10000.0: 14
Number of HSP's gapped: 14
Number of HSP's successfully gapped: 14
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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