Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              18    1935
XP_006718908                                                           18    1935
XP_005271621                                                           18    1935
XP_006718907                                                           18    1935
XP_006718906                                                           18    1935
XP_005271619                                                           18    1935
XP_005271618                                                           18    1935
NP_001129396                                                           18    1935
XP_005252323                                                           17    3301
XP_005252322                                                           17    3301
XP_005252321                                                           17    3301
XP_005252320                                                           17    3301
NP_001092272                                                           17    3301
NP_115547                                                              17    3301
NP_955776                                                              17    4312
NP_001191023                                                           17    4312
NP_002838                                                              17    4312
NP_056202                                                              17    4312
NP_001094289                                                           17    4312
NP_001189414                                                           17    4312
NP_056342                                                              17    4312
XP_006716138                                                           17    4312
NP_570857                                                              17    4312
NP_570858                                                              17    4312
NP_005472                                                              16    5631
XP_006722663                                                           16    5631
XP_005270208                                                           16    5631
XP_005270207                                                           16    5631
XP_005270206                                                           16    5631
NP_077302                                                              16    5631
NP_001258463                                                           16    7355
NP_001380                                                              16    7355
NP_001243757                                                           16    7355
NP_001269255                                                           16    7355
NP_001243756                                                           16    7355
NP_060045                                                              16    7355
NP_001073887                                                           16    7355
XP_006724038                                                           16    7355
XP_005256628                                                           16    7355
XP_005256627                                                           16    7355
XP_006721558                                                           16    7355
XP_006721557                                                           16    7355
XP_006721556                                                           16    7355
XP_005256626                                                           16    7355
XP_005271148                                                           16    7355
NP_612486                                                              15    9605
NP_001013860                                                           15    9605
NP_714544                                                              15    9605
XP_006721205                                                           15    9605
XP_005255864                                                           15    9605
XP_006721204                                                           15    9605
XP_006721203                                                           15    9605
XP_006721202                                                           15    9605
XP_006721201                                                           15    9605
XP_006720470                                                           15    9605
XP_005254235                                                           15    9605
XP_005254233                                                           15    9605
XP_005254234                                                           15    9605
>NP_000042
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELDGLALR 9
            LELD LALR
Sbjct: 2445 LELDELALR 2453
>XP_006718908
          Length = 1708

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELDGLALR 9
            LELD LALR
Sbjct: 1097 LELDELALR 1105
>XP_005271621
          Length = 2708

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELDGLALR 9
            LELD LALR
Sbjct: 2097 LELDELALR 2105
>XP_006718907
          Length = 3050

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELDGLALR 9
            LELD LALR
Sbjct: 2439 LELDELALR 2447
>XP_006718906
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELDGLALR 9
            LELD LALR
Sbjct: 2445 LELDELALR 2453
>XP_005271619
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELDGLALR 9
            LELD LALR
Sbjct: 2445 LELDELALR 2453
>XP_005271618
          Length = 3056

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    LELDGLALR 9
            LELD LALR
Sbjct: 2445 LELDELALR 2453
>NP_001129396
          Length = 1590

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LELDGLALR 9
           LELDG+ LR
Sbjct: 251 LELDGINLR 259
>XP_005252323
          Length = 635

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  LELDGLALR 9
          LEL+GL LR
Sbjct: 38 LELNGLILR 46
>XP_005252322
          Length = 690

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LELDGLALR 9
           LEL+GL LR
Sbjct: 125 LELNGLILR 133
>XP_005252321
          Length = 696

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LELDGLALR 9
           LEL+GL LR
Sbjct: 125 LELNGLILR 133
>XP_005252320
          Length = 706

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LELDGLALR 9
           LEL+GL LR
Sbjct: 125 LELNGLILR 133
>NP_001092272
          Length = 722

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LELDGLALR 9
           LEL+GL LR
Sbjct: 125 LELNGLILR 133
>NP_115547
          Length = 706

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   LELDGLALR 9
           LEL+GL LR
Sbjct: 125 LELNGLILR 133
>NP_955776
          Length = 193

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  LELDGLALR 9
          LEL+GLA++
Sbjct: 47 LELNGLAVK 55
>NP_001191023
          Length = 193

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  LELDGLALR 9
          LEL+GLA++
Sbjct: 47 LELNGLAVK 55
>NP_002838
          Length = 1015

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LELDGLA 7
           LELDG+A
Sbjct: 327 LELDGMA 333
>NP_056202
          Length = 225

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  LELDGLALR 9
          LEL+GLA++
Sbjct: 79 LELNGLAVK 87
>NP_001094289
          Length = 204

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  LELDGLALR 9
          LEL+GLA++
Sbjct: 58 LELNGLAVK 66
>NP_001189414
          Length = 261

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LELDGLALR 9
           LEL+GLA++
Sbjct: 115 LELNGLAVK 123
>NP_056342
          Length = 808

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ELDGLALR 9
           E++GLALR
Sbjct: 295 EINGLALR 302
>XP_006716138
          Length = 858

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LELDGLA 7
           LELDG+A
Sbjct: 327 LELDGMA 333
>NP_570857
          Length = 998

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LELDGLA 7
           LELDG+A
Sbjct: 310 LELDGMA 316
>NP_570858
          Length = 986

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LELDGLA 7
           LELDG+A
Sbjct: 327 LELDGMA 333
>NP_005472
          Length = 877

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LELDGLA 7
           L+LDGLA
Sbjct: 765 LQLDGLA 771
>XP_006722663
          Length = 877

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LELDGLA 7
           L+LDGLA
Sbjct: 765 LQLDGLA 771
>XP_005270208
          Length = 300

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDGLALR 9
           +DGLALR
Sbjct: 153 VDGLALR 159
>XP_005270207
          Length = 300

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDGLALR 9
           +DGLALR
Sbjct: 153 VDGLALR 159
>XP_005270206
          Length = 387

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDGLALR 9
           +DGLALR
Sbjct: 240 VDGLALR 246
>NP_077302
          Length = 300

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDGLALR 9
           +DGLALR
Sbjct: 153 VDGLALR 159
>NP_001258463
          Length = 1994

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LELDGL 6
            LELDGL
Sbjct: 1150 LELDGL 1155
>NP_001380
          Length = 2012

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LELDGL 6
            LELDGL
Sbjct: 1150 LELDGL 1155
>NP_001243757
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   ELDGLA 7
           ELDGLA
Sbjct: 374 ELDGLA 379
>NP_001269255
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   ELDGLA 7
           ELDGLA
Sbjct: 193 ELDGLA 198
>NP_001243756
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   ELDGLA 7
           ELDGLA
Sbjct: 374 ELDGLA 379
>NP_060045
          Length = 1419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LDGLALR 9
           +DGLA+R
Sbjct: 704 MDGLAIR 710

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ELDGLA 7
            ELDGLA
Sbjct: 1282 ELDGLA 1287
>NP_001073887
          Length = 979

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LELDGLA 7
           LEL+GLA
Sbjct: 685 LELEGLA 691
>XP_006724038
          Length = 1907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    LELDGL 6
            LELDGL
Sbjct: 1045 LELDGL 1050
>XP_005256628
          Length = 511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   ELDGLA 7
           ELDGLA
Sbjct: 374 ELDGLA 379
>XP_005256627
          Length = 899

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LDGLALR 9
           +DGLA+R
Sbjct: 704 MDGLAIR 710
>XP_006721558
          Length = 909

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LDGLALR 9
           +DGLA+R
Sbjct: 704 MDGLAIR 710
>XP_006721557
          Length = 918

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LDGLALR 9
           +DGLA+R
Sbjct: 704 MDGLAIR 710
>XP_006721556
          Length = 1357

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LDGLALR 9
           +DGLA+R
Sbjct: 704 MDGLAIR 710

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ELDGLA 7
            ELDGLA
Sbjct: 1220 ELDGLA 1225
>XP_005256626
          Length = 1388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LDGLALR 9
           +DGLA+R
Sbjct: 673 MDGLAIR 679

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ELDGLA 7
            ELDGLA
Sbjct: 1251 ELDGLA 1256
>XP_005271148
          Length = 979

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LELDGLA 7
           LEL+GLA
Sbjct: 685 LELEGLA 691
>NP_612486
          Length = 1227

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ELDGLAL 8
           EL+GLAL
Sbjct: 597 ELNGLAL 603
>NP_001013860
          Length = 1435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LDGLAL 8
           LDGLAL
Sbjct: 483 LDGLAL 488
>NP_714544
          Length = 1775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    LELDGLAL 8
            L+LD LAL
Sbjct: 1143 LQLDSLAL 1150
>XP_006721205
          Length = 1441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LDGLAL 8
           LDGLAL
Sbjct: 483 LDGLAL 488
>XP_005255864
          Length = 1372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LDGLAL 8
           LDGLAL
Sbjct: 447 LDGLAL 452
>XP_006721204
          Length = 1405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LDGLAL 8
           LDGLAL
Sbjct: 447 LDGLAL 452
>XP_006721203
          Length = 1408

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LDGLAL 8
           LDGLAL
Sbjct: 483 LDGLAL 488
>XP_006721202
          Length = 1424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LDGLAL 8
           LDGLAL
Sbjct: 483 LDGLAL 488
>XP_006721201
          Length = 1430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LDGLAL 8
           LDGLAL
Sbjct: 483 LDGLAL 488
>XP_006720470
          Length = 1017

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LELDGLAL 8
           L+LD LAL
Sbjct: 385 LQLDSLAL 392
>XP_005254235
          Length = 1017

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ELDGLAL 8
           EL+GLAL
Sbjct: 598 ELNGLAL 604
>XP_005254233
          Length = 1228

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ELDGLAL 8
           EL+GLAL
Sbjct: 598 ELNGLAL 604
>XP_005254234
          Length = 1076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ELDGLAL 8
           EL+GLAL
Sbjct: 598 ELNGLAL 604
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.153    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 462,250
Number of extensions: 638
Number of successful extensions: 61
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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