Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245200                                                           20     390
NP_000240                                                              20     390
XP_005265218                                                           20     390
NP_056999                                                              20     509
NP_853629                                                              20     509
NP_001121185                                                           20     509
NP_001061                                                              18    1935
NP_056445                                                              18    1935
XP_005257280                                                           18    1935
XP_005257279                                                           18    1935
XP_006712474                                                           18    1935
NP_057521                                                              18    1935
XP_005264070                                                           17    3301
NP_789795                                                              17    3301
NP_001047                                                              17    3301
NP_005844                                                              17    4312
NP_001239126                                                           17    4312
NP_001123537                                                           16    5631
NP_055746                                                              16    5631
NP_004136                                                              16    5631
XP_005258727                                                           16    5631
XP_005258726                                                           16    5631
XP_006722820                                                           16    5631
XP_005259972                                                           16    5631
XP_006722819                                                           16    5631
XP_006722818                                                           16    5631
NP_055558                                                              16    7355
NP_001094060                                                           16    7355
XP_005248098                                                           16    7355
XP_006713998                                                           16    7355
XP_006713997                                                           16    7355
NP_000979                                                              16    7355
NP_001077430                                                           15    9605
NP_525128                                                              15    9605
NP_775907                                                              15    9605
NP_612355                                                              15    9605
NP_001164100                                                           15    9605
NP_001554                                                              15    9605
NP_001269297                                                           15    9605
NP_065971                                                              15    9605
NP_001241657                                                           15    9605
NP_001241658                                                           15    9605
NP_055592                                                              15    9605
NP_001121598                                                           15    9605
NP_055073                                                              15    9605
NP_001180438                                                           15    9605
NP_002724                                                              15    9605
NP_060205                                                              15    9605
NP_001193639                                                           15    9605
XP_006726657                                                           15    9605
XP_006725285                                                           15    9605
XP_006723744                                                           15    9605
XP_005260304                                                           15    9605
XP_005258866                                                           15    9605
XP_005269077                                                           15    9605
XP_006719563                                                           15    9605
XP_006719562                                                           15    9605
XP_005269076                                                           15    9605
XP_005253197                                                           15    9605
XP_005264473                                                           15    9605
XP_005273417                                                           15    9605
XP_005263588                                                           15    9605
NP_001193638                                                           15    9605
NP_001035792                                                           15    9605
NP_065954                                                              15    9605
>NP_001245200
          Length = 687

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  LDETVLNRI 9
          LDETV+NRI
Sbjct: 11 LDETVVNRI 19
>NP_000240
          Length = 756

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  LDETVLNRI 9
          LDETV+NRI
Sbjct: 11 LDETVVNRI 19
>XP_005265218
          Length = 687

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  LDETVLNRI 9
          LDETV+NRI
Sbjct: 11 LDETVVNRI 19
>NP_056999
          Length = 558

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LDETVLNRI 9
          LDET LNRI
Sbjct: 48 LDETALNRI 56
>NP_853629
          Length = 553

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LDETVLNRI 9
          LDET LNRI
Sbjct: 48 LDETALNRI 56
>NP_001121185
          Length = 553

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LDETVLNRI 9
          LDET LNRI
Sbjct: 48 LDETALNRI 56
>NP_001061
          Length = 451

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LDETVLNRI 9
           LD T LNRI
Sbjct: 205 LDNTALNRI 213
>NP_056445
          Length = 807

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   DETVLNRI 9
           DET+LNR+
Sbjct: 121 DETLLNRL 128
>XP_005257280
          Length = 298

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  LDETVLNRI 9
          LD T LNRI
Sbjct: 52 LDNTALNRI 60
>XP_005257279
          Length = 460

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LDETVLNRI 9
           LD T LNRI
Sbjct: 214 LDNTALNRI 222
>XP_006712474
          Length = 689

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  DETVLNRI 9
          DET+LNR+
Sbjct: 5  DETLLNRL 12
>NP_057521
          Length = 451

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LDETVLNRI 9
           LD T LNRI
Sbjct: 205 LDNTALNRI 213
>XP_005264070
          Length = 298

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LDETVLNRI 9
           +DETVL++I
Sbjct: 218 VDETVLDKI 226
>NP_789795
          Length = 307

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LDETVLNRI 9
           +DETVL++I
Sbjct: 227 VDETVLDKI 235
>NP_001047
          Length = 296

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   LDETVLNRI 9
           +DETVL++I
Sbjct: 216 VDETVLDKI 224
>NP_005844
          Length = 483

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LDETVLNR 8
           L++TVLNR
Sbjct: 442 LNQTVLNR 449
>NP_001239126
          Length = 482

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LDETVLNR 8
           L++TVLNR
Sbjct: 441 LNQTVLNR 448
>NP_001123537
          Length = 2022

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LDETVLNRI 9
            LDE +LN+I
Sbjct: 1514 LDEFLLNKI 1522
>NP_055746
          Length = 881

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   DETVLNRI 9
           DE++LNR+
Sbjct: 99  DESLLNRL 106
>NP_004136
          Length = 2157

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LDETVLNRI 9
            LDE +LN+I
Sbjct: 1514 LDEFLLNKI 1522
>XP_005258727
          Length = 881

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   DETVLNRI 9
           DE++LNR+
Sbjct: 99  DESLLNRL 106
>XP_005258726
          Length = 881

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   DETVLNRI 9
           DE++LNR+
Sbjct: 99  DESLLNRL 106
>XP_006722820
          Length = 2140

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LDETVLNRI 9
            LDE +LN+I
Sbjct: 1514 LDEFLLNKI 1522
>XP_005259972
          Length = 2141

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LDETVLNRI 9
            LDE +LN+I
Sbjct: 1514 LDEFLLNKI 1522
>XP_006722819
          Length = 2156

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LDETVLNRI 9
            LDE +LN+I
Sbjct: 1514 LDEFLLNKI 1522
>XP_006722818
          Length = 2157

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LDETVLNRI 9
            LDE +LN+I
Sbjct: 1514 LDEFLLNKI 1522
>NP_055558
          Length = 1395

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LDETVLN 7
           LD TVLN
Sbjct: 618 LDSTVLN 624
>NP_001094060
          Length = 1395

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LDETVLN 7
           LD TVLN
Sbjct: 618 LDSTVLN 624
>XP_005248098
          Length = 1310

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LDETVLN 7
           LD TVLN
Sbjct: 509 LDSTVLN 515
>XP_006713998
          Length = 1332

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LDETVLN 7
           LD TVLN
Sbjct: 618 LDSTVLN 624
>XP_006713997
          Length = 1419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LDETVLN 7
           LD TVLN
Sbjct: 618 LDSTVLN 624
>NP_000979
          Length = 136

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LDETVLNR 8
          LD+TV+N+
Sbjct: 91 LDKTVVNK 98
>NP_001077430
          Length = 1523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  DETVLNRI 9
          +ETV NR+
Sbjct: 53 EETVQNRV 60
>NP_525128
          Length = 72

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  DETVLNR 8
          DE++LNR
Sbjct: 63 DESLLNR 69
>NP_775907
          Length = 1518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  DETVLNRI 9
          +ETV NR+
Sbjct: 53 EETVQNRV 60
>NP_612355
          Length = 634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LDETVL 6
           LDETVL
Sbjct: 281 LDETVL 286
>NP_001164100
          Length = 2581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    ETVLNRI 9
            ETV NR+
Sbjct: 2399 ETVFNRV 2405
>NP_001554
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DETVLNRI 9
           D+T+LN I
Sbjct: 202 DDTLLNEI 209
>NP_001269297
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DETVLNRI 9
           D+T+LN I
Sbjct: 124 DDTLLNEI 131
>NP_065971
          Length = 2302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    ETVLNRI 9
            ETV NR+
Sbjct: 2120 ETVFNRV 2126
>NP_001241657
          Length = 144

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LDETVLN 7
           LDE VLN
Sbjct: 114 LDEMVLN 120
>NP_001241658
          Length = 144

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LDETVLN 7
           LDE VLN
Sbjct: 114 LDEMVLN 120
>NP_055592
          Length = 1524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ETVLNRI 9
           +TVLNR+
Sbjct: 279 DTVLNRL 285
>NP_001121598
          Length = 144

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LDETVLN 7
           LDE VLN
Sbjct: 114 LDEMVLN 120
>NP_055073
          Length = 1530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   DETVLNRI 9
           DE VLN I
Sbjct: 119 DEAVLNMI 126
>NP_001180438
          Length = 793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DETVLNRI 9
           D+T+LN I
Sbjct: 269 DDTILNDI 276
>NP_002724
          Length = 331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   ETVLNRI 9
           ET++NR+
Sbjct: 286 ETIINRL 292
>NP_060205
          Length = 843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DETVLNRI 9
           D+T+LN I
Sbjct: 319 DDTILNDI 326
>NP_001193639
          Length = 299

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   ETVLNRI 9
           ET++NR+
Sbjct: 254 ETIINRL 260
>XP_006726657
          Length = 633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LDETVL 6
           LDETVL
Sbjct: 281 LDETVL 286
>XP_006725285
          Length = 633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LDETVL 6
           LDETVL
Sbjct: 281 LDETVL 286
>XP_006723744
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   DETVLNRI 9
           DE VLN I
Sbjct: 119 DEAVLNMI 126
>XP_005260304
          Length = 1530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   DETVLNRI 9
           DE VLN I
Sbjct: 119 DEAVLNMI 126
>XP_005258866
          Length = 1486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  DETVLNRI 9
          +ETV NR+
Sbjct: 53 EETVQNRV 60
>XP_005269077
          Length = 247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   ETVLNRI 9
           ET++NR+
Sbjct: 202 ETIINRL 208
>XP_006719563
          Length = 280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   ETVLNRI 9
           ET++NR+
Sbjct: 235 ETIINRL 241
>XP_006719562
          Length = 299

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   ETVLNRI 9
           ET++NR+
Sbjct: 254 ETIINRL 260
>XP_005269076
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   ETVLNRI 9
           ET++NR+
Sbjct: 323 ETIINRL 329
>XP_005253197
          Length = 786

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   DETVLNR 8
           DET LNR
Sbjct: 699 DETNLNR 705
>XP_005264473
          Length = 802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DETVLNRI 9
           D+T+LN I
Sbjct: 319 DDTILNDI 326
>XP_005273417
          Length = 1487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ETVLNRI 9
           +TVLNR+
Sbjct: 279 DTVLNRL 285
>XP_005263588
          Length = 667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LDETVL 6
           LDETVL
Sbjct: 281 LDETVL 286
>NP_001193638
          Length = 340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   ETVLNRI 9
           ET++NR+
Sbjct: 295 ETIINRL 301
>NP_001035792
          Length = 72

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  DETVLNR 8
          DE++LNR
Sbjct: 63 DESLLNR 69
>NP_065954
          Length = 922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   LDETVL 6
           LDETVL
Sbjct: 238 LDETVL 243
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.143    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 449,915
Number of extensions: 820
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package