Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005219                                                              20     509
NP_001276866                                                           20     509
NP_004439                                                              20     509
NP_001276865                                                           20     509
NP_001005862                                                           20     509
XP_005257197                                                           20     509
XP_006721828                                                           20     509
NP_789786                                                              17    4312
XP_005276824                                                           17    4312
XP_005276823                                                           17    4312
XP_005276822                                                           17    4312
XP_006726278                                                           17    4312
XP_005276821                                                           17    4312
XP_006726277                                                           17    4312
XP_005276820                                                           17    4312
XP_005276819                                                           17    4312
XP_005276818                                                           17    4312
XP_005248520                                                           17    4312
XP_005248519                                                           17    4312
XP_005248518                                                           17    4312
XP_006714633                                                           17    4312
XP_005248517                                                           17    4312
XP_006714632                                                           17    4312
XP_005248516                                                           17    4312
XP_005248515                                                           17    4312
XP_005248514                                                           17    4312
NP_000373                                                              16    7355
NP_001026976                                                           16    7355
NP_006493                                                              15    9605
NP_001036064                                                           15    9605
NP_005226                                                              15    9605
NP_001277185                                                           15    9605
NP_056114                                                              15    9605
NP_001277186                                                           15    9605
NP_003175                                                              15    9605
NP_997210                                                              15    9605
XP_005267533                                                           15    9605
XP_005267531                                                           15    9605
XP_005267530                                                           15    9605
XP_006716684                                                           15    9605
XP_005249243                                                           15    9605
XP_005246434                                                           15    9605
XP_005246433                                                           15    9605
XP_005246432                                                           15    9605
XP_006712427                                                           15    9605
>NP_005219
          Length = 1210

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LDEAYVMA 8
           LDEAYVMA
Sbjct: 760 LDEAYVMA 767
>NP_001276866
          Length = 1055

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LDEAYVMA 8
           LDEAYVMA
Sbjct: 768 LDEAYVMA 775
>NP_004439
          Length = 1255

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LDEAYVMA 8
           LDEAYVMA
Sbjct: 768 LDEAYVMA 775
>NP_001276865
          Length = 1240

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LDEAYVMA 8
           LDEAYVMA
Sbjct: 753 LDEAYVMA 760
>NP_001005862
          Length = 1225

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LDEAYVMA 8
           LDEAYVMA
Sbjct: 738 LDEAYVMA 745
>XP_005257197
          Length = 1225

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LDEAYVMA 8
           LDEAYVMA
Sbjct: 738 LDEAYVMA 745
>XP_006721828
          Length = 1336

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   LDEAYVMA 8
           LDEAYVMA
Sbjct: 849 LDEAYVMA 856
>NP_789786
          Length = 511

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DEAYVMA 8
           +EAYVMA
Sbjct: 317 EEAYVMA 323
>XP_005276824
          Length = 386

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DEAYVMA 8
           +EAYVMA
Sbjct: 192 EEAYVMA 198
>XP_005276823
          Length = 386

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DEAYVMA 8
           +EAYVMA
Sbjct: 192 EEAYVMA 198
>XP_005276822
          Length = 421

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DEAYVMA 8
           +EAYVMA
Sbjct: 227 EEAYVMA 233
>XP_006726278
          Length = 434

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DEAYVMA 8
           +EAYVMA
Sbjct: 240 EEAYVMA 246
>XP_005276821
          Length = 438

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DEAYVMA 8
           +EAYVMA
Sbjct: 244 EEAYVMA 250
>XP_006726277
          Length = 506

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DEAYVMA 8
           +EAYVMA
Sbjct: 312 EEAYVMA 318
>XP_005276820
          Length = 510

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DEAYVMA 8
           +EAYVMA
Sbjct: 316 EEAYVMA 322
>XP_005276819
          Length = 511

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DEAYVMA 8
           +EAYVMA
Sbjct: 317 EEAYVMA 323
>XP_005276818
          Length = 511

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DEAYVMA 8
           +EAYVMA
Sbjct: 317 EEAYVMA 323
>XP_005248520
          Length = 386

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DEAYVMA 8
           +EAYVMA
Sbjct: 192 EEAYVMA 198
>XP_005248519
          Length = 386

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DEAYVMA 8
           +EAYVMA
Sbjct: 192 EEAYVMA 198
>XP_005248518
          Length = 421

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DEAYVMA 8
           +EAYVMA
Sbjct: 227 EEAYVMA 233
>XP_006714633
          Length = 434

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DEAYVMA 8
           +EAYVMA
Sbjct: 240 EEAYVMA 246
>XP_005248517
          Length = 438

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DEAYVMA 8
           +EAYVMA
Sbjct: 244 EEAYVMA 250
>XP_006714632
          Length = 506

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DEAYVMA 8
           +EAYVMA
Sbjct: 312 EEAYVMA 318
>XP_005248516
          Length = 510

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DEAYVMA 8
           +EAYVMA
Sbjct: 316 EEAYVMA 322
>XP_005248515
          Length = 511

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DEAYVMA 8
           +EAYVMA
Sbjct: 317 EEAYVMA 323
>XP_005248514
          Length = 511

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   DEAYVMA 8
           +EAYVMA
Sbjct: 317 EEAYVMA 323
>NP_000373
          Length = 485

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  LDEAYV 6
          LDEAY+
Sbjct: 92 LDEAYI 97
>NP_001026976
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  LDEAYV 6
          LDEAY+
Sbjct: 92 LDEAYI 97
>NP_006493
          Length = 713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   LDEAYV 6
           +DEAYV
Sbjct: 114 IDEAYV 119
>NP_001036064
          Length = 1292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LDEAYVMA 8
           +DEA +MA
Sbjct: 766 MDEALIMA 773
>NP_005226
          Length = 1308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LDEAYVMA 8
           +DEA +MA
Sbjct: 766 MDEALIMA 773
>NP_001277185
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDEAYVMA 8
           L EA+VMA
Sbjct: 165 LTEAFVMA 172
>NP_056114
          Length = 678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDEAYVMA 8
           L EA+VMA
Sbjct: 124 LTEAFVMA 131
>NP_001277186
          Length = 678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDEAYVMA 8
           L EA+VMA
Sbjct: 124 LTEAFVMA 131
>NP_003175
          Length = 1199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   LDEAYV 6
           +DEAYV
Sbjct: 309 IDEAYV 314
>NP_997210
          Length = 123

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LDEAYVM 7
          L+E+YVM
Sbjct: 40 LEESYVM 46
>XP_005267533
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDEAYVMA 8
           L EA+VMA
Sbjct: 209 LTEAFVMA 216
>XP_005267531
          Length = 678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDEAYVMA 8
           L EA+VMA
Sbjct: 124 LTEAFVMA 131
>XP_005267530
          Length = 763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LDEAYVMA 8
           L EA+VMA
Sbjct: 209 LTEAFVMA 216
>XP_006716684
          Length = 1251

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   LDEAYV 6
           +DEAYV
Sbjct: 309 IDEAYV 314
>XP_005249243
          Length = 651

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  LDEAYV 6
          +DEAYV
Sbjct: 52 IDEAYV 57
>XP_005246434
          Length = 1282

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LDEAYVMA 8
           +DEA +MA
Sbjct: 756 MDEALIMA 763
>XP_005246433
          Length = 1298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LDEAYVMA 8
           +DEA +MA
Sbjct: 756 MDEALIMA 763
>XP_005246432
          Length = 1307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LDEAYVMA 8
           +DEA +MA
Sbjct: 781 MDEALIMA 788
>XP_006712427
          Length = 1323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LDEAYVMA 8
           +DEA +MA
Sbjct: 781 MDEALIMA 788
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.134    0.347 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 429,161
Number of extensions: 340
Number of successful extensions: 45
Number of sequences better than 10000.0: 45
Number of HSP's gapped: 45
Number of HSP's successfully gapped: 45
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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