Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005148                                                              20     509
NP_009297                                                              20     509
NP_001103224                                                           19     869
XP_006719593                                                           19     869
XP_006719591                                                           19     869
NP_659491                                                              18    1935
NP_009049                                                              17    2528
NP_848652                                                              17    2528
XP_006714558                                                           17    2528
XP_006710219                                                           17    2528
NP_789787                                                              17    4312
NP_001026                                                              16    5631
NP_001019831                                                           16    5631
NP_001186127                                                           16    5631
NP_060779                                                              16    5631
NP_001693                                                              16    5631
XP_006726780                                                           16    5631
XP_006721690                                                           16    5631
XP_005251072                                                           16    5631
XP_006713877                                                           16    5631
XP_006713876                                                           16    5631
XP_006713875                                                           16    5631
XP_006713874                                                           16    5631
XP_006713873                                                           16    5631
XP_006711873                                                           16    5631
XP_006711872                                                           16    5631
XP_006711871                                                           16    5631
XP_006711870                                                           16    5631
XP_006711869                                                           16    5631
XP_006711868                                                           16    5631
XP_006711867                                                           16    5631
XP_006711866                                                           16    5631
XP_006711865                                                           16    5631
XP_006710091                                                           16    5631
NP_064610                                                              16    7355
NP_543007                                                              16    7355
NP_001245175                                                           16    7355
NP_001245171                                                           16    7355
NP_001245172                                                           16    7355
NP_001245173                                                           16    7355
NP_001245167                                                           16    7355
NP_001245174                                                           16    7355
NP_001245170                                                           16    7355
NP_001245176                                                           16    7355
NP_001245169                                                           16    7355
NP_001245168                                                           16    7355
NP_001122312                                                           16    7355
NP_001122311                                                           16    7355
NP_001074015                                                           16    7355
XP_006718846                                                           16    7355
XP_006718845                                                           16    7355
XP_006718844                                                           16    7355
XP_006718843                                                           16    7355
XP_006718842                                                           16    7355
XP_005263199                                                           16    7355
XP_005265505                                                           16    7355
NP_064629                                                              16    7355
NP_062545                                                              16    7355
NP_057658                                                              15    9605
NP_000786                                                              15    9605
NP_006500                                                              15    9605
NP_066363                                                              15    9605
XP_006723899                                                           15    9605
XP_005259185                                                           15    9605
XP_005259184                                                           15    9605
XP_006718837                                                           15    9605
XP_005271482                                                           15    9605
XP_005266875                                                           15    9605
XP_005249232                                                           15    9605
NP_060426                                                              15    9605
>NP_005148
          Length = 1130

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LCLAISRSS 9
            LCLAISR+S
Sbjct: 1039 LCLAISRNS 1047
>NP_009297
          Length = 1149

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    LCLAISRSS 9
            LCLAISR+S
Sbjct: 1058 LCLAISRNS 1066
>NP_001103224
          Length = 2215

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LCLAISRSS 9
          LCLAIS SS
Sbjct: 67 LCLAISNSS 75
>XP_006719593
          Length = 1304

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LCLAISRSS 9
          LCLAIS SS
Sbjct: 67 LCLAISNSS 75
>XP_006719591
          Length = 2230

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  LCLAISRSS 9
          LCLAIS SS
Sbjct: 67 LCLAISNSS 75
>NP_659491
          Length = 620

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2  CLAISRS 8
          CLAISRS
Sbjct: 69 CLAISRS 75
>NP_009049
          Length = 3097

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    LCLAISRSS 9
            LC+A SRSS
Sbjct: 1716 LCIAHSRSS 1724
>NP_848652
          Length = 302

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LCLAISRS 8
           LC A+SRS
Sbjct: 127 LCFAVSRS 134
>XP_006714558
          Length = 2612

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    LCLAISRSS 9
            LC+A SRSS
Sbjct: 1231 LCIAHSRSS 1239
>XP_006710219
          Length = 218

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LCLAISRS 8
          LC A+SRS
Sbjct: 43 LCFAVSRS 50
>NP_789787
          Length = 333

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  LCLAISR 7
          LCL+ISR
Sbjct: 58 LCLSISR 64
>NP_001026
          Length = 4967

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   CLAISRSS 9
           CL+ SRSS
Sbjct: 132 CLSTSRSS 139
>NP_001019831
          Length = 2986

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LCLAISRSS 9
            LC++ SRSS
Sbjct: 1706 LCISHSRSS 1714
>NP_001186127
          Length = 699

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LCLAISRS 8
           LCLAIS S
Sbjct: 316 LCLAISVS 323
>NP_060779
          Length = 684

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   LCLAISRS 8
           LCLAIS S
Sbjct: 316 LCLAISVS 323
>NP_001693
          Length = 1584

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   CLAISRSS 9
           CLA SRSS
Sbjct: 196 CLAGSRSS 203
>XP_006726780
          Length = 293

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LCLAISRSS 9
           LCLA+S S+
Sbjct: 216 LCLAVSVSA 224
>XP_006721690
          Length = 293

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LCLAISRSS 9
           LCLA+S S+
Sbjct: 216 LCLAVSVSA 224
>XP_005251072
          Length = 1586

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   CLAISRSS 9
           CLA SRSS
Sbjct: 196 CLAGSRSS 203
>XP_006713877
          Length = 2956

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LCLAISRSS 9
            LC++ SRSS
Sbjct: 1708 LCISHSRSS 1716
>XP_006713876
          Length = 2966

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LCLAISRSS 9
            LC++ SRSS
Sbjct: 1686 LCISHSRSS 1694
>XP_006713875
          Length = 2975

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LCLAISRSS 9
            LC++ SRSS
Sbjct: 1695 LCISHSRSS 1703
>XP_006713874
          Length = 2979

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LCLAISRSS 9
            LC++ SRSS
Sbjct: 1699 LCISHSRSS 1707
>XP_006713873
          Length = 2988

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LCLAISRSS 9
            LC++ SRSS
Sbjct: 1708 LCISHSRSS 1716
>XP_006711873
          Length = 4954

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   CLAISRSS 9
           CL+ SRSS
Sbjct: 132 CLSTSRSS 139
>XP_006711872
          Length = 2735

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   CLAISRSS 9
           CL+ SRSS
Sbjct: 132 CLSTSRSS 139
>XP_006711871
          Length = 4906

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   CLAISRSS 9
           CL+ SRSS
Sbjct: 132 CLSTSRSS 139
>XP_006711870
          Length = 4965

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   CLAISRSS 9
           CL+ SRSS
Sbjct: 132 CLSTSRSS 139
>XP_006711869
          Length = 4973

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   CLAISRSS 9
           CL+ SRSS
Sbjct: 132 CLSTSRSS 139
>XP_006711868
          Length = 4975

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   CLAISRSS 9
           CL+ SRSS
Sbjct: 132 CLSTSRSS 139
>XP_006711867
          Length = 4977

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   CLAISRSS 9
           CL+ SRSS
Sbjct: 132 CLSTSRSS 139
>XP_006711866
          Length = 4984

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   CLAISRSS 9
           CL+ SRSS
Sbjct: 132 CLSTSRSS 139
>XP_006711865
          Length = 4985

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   CLAISRSS 9
           CL+ SRSS
Sbjct: 132 CLSTSRSS 139
>XP_006710091
          Length = 293

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LCLAISRSS 9
           LCLA+S S+
Sbjct: 216 LCLAVSVSA 224
>NP_064610
          Length = 926

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  LCLAIS 6
          LCLAIS
Sbjct: 78 LCLAIS 83
>NP_543007
          Length = 336

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   CLAISRSS 9
           CLA +RSS
Sbjct: 296 CLASARSS 303
>NP_001245175
          Length = 150

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LCLAISRSS 9
          LC+ +SR+S
Sbjct: 60 LCVLLSRAS 68
>NP_001245171
          Length = 150

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LCLAISRSS 9
          LC+ +SR+S
Sbjct: 60 LCVLLSRAS 68
>NP_001245172
          Length = 150

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LCLAISRSS 9
          LC+ +SR+S
Sbjct: 60 LCVLLSRAS 68
>NP_001245173
          Length = 115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LCLAISRSS 9
          LC+ +SR+S
Sbjct: 25 LCVLLSRAS 33
>NP_001245167
          Length = 115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LCLAISRSS 9
          LC+ +SR+S
Sbjct: 25 LCVLLSRAS 33
>NP_001245174
          Length = 115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LCLAISRSS 9
          LC+ +SR+S
Sbjct: 25 LCVLLSRAS 33
>NP_001245170
          Length = 115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LCLAISRSS 9
          LC+ +SR+S
Sbjct: 25 LCVLLSRAS 33
>NP_001245176
          Length = 115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LCLAISRSS 9
          LC+ +SR+S
Sbjct: 25 LCVLLSRAS 33
>NP_001245169
          Length = 115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LCLAISRSS 9
          LC+ +SR+S
Sbjct: 25 LCVLLSRAS 33
>NP_001245168
          Length = 150

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LCLAISRSS 9
          LC+ +SR+S
Sbjct: 60 LCVLLSRAS 68
>NP_001122312
          Length = 2161

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LCLAISRS 8
           LC AIS+S
Sbjct: 492 LCQAISKS 499
>NP_001122311
          Length = 2137

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LCLAISRS 8
           LC AIS+S
Sbjct: 492 LCQAISKS 499
>NP_001074015
          Length = 115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LCLAISRSS 9
          LC+ +SR+S
Sbjct: 25 LCVLLSRAS 33
>XP_006718846
          Length = 115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LCLAISRSS 9
          LC+ +SR+S
Sbjct: 25 LCVLLSRAS 33
>XP_006718845
          Length = 150

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LCLAISRSS 9
          LC+ +SR+S
Sbjct: 60 LCVLLSRAS 68
>XP_006718844
          Length = 150

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LCLAISRSS 9
          LC+ +SR+S
Sbjct: 60 LCVLLSRAS 68
>XP_006718843
          Length = 150

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LCLAISRSS 9
          LC+ +SR+S
Sbjct: 60 LCVLLSRAS 68
>XP_006718842
          Length = 150

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  LCLAISRSS 9
          LC+ +SR+S
Sbjct: 60 LCVLLSRAS 68
>XP_005263199
          Length = 863

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  LCLAIS 6
          LCLAIS
Sbjct: 78 LCLAIS 83
>XP_005265505
          Length = 2146

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LCLAISRS 8
           LC AIS+S
Sbjct: 492 LCQAISKS 499
>NP_064629
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   LCLAISR 7
           LCL ISR
Sbjct: 369 LCLQISR 375
>NP_062545
          Length = 299

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  CLAISR 7
          CLA+SR
Sbjct: 50 CLAVSR 55
>NP_057658
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1  LCLAISR 7
          +C+A+SR
Sbjct: 55 VCMAVSR 61
>NP_000786
          Length = 443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1  LCLAISR 7
          +C+A+SR
Sbjct: 55 VCMAVSR 61
>NP_006500
          Length = 579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LCLAISRSS 9
          L LA+SRS+
Sbjct: 43 LSLAVSRST 51
>NP_066363
          Length = 1918

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    LCLAISRS 8
            +C+A+SR+
Sbjct: 1217 ICVALSRA 1224
>XP_006723899
          Length = 1918

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    LCLAISRS 8
            +C+A+SR+
Sbjct: 1217 ICVALSRA 1224
>XP_005259185
          Length = 507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LCLAISRSS 9
          L LA+SRS+
Sbjct: 43 LSLAVSRST 51
>XP_005259184
          Length = 576

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  LCLAISRSS 9
          L LA+SRS+
Sbjct: 43 LSLAVSRST 51
>XP_006718837
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1  LCLAISR 7
          +C+A+SR
Sbjct: 55 VCMAVSR 61
>XP_005271482
          Length = 443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1  LCLAISR 7
          +C+A+SR
Sbjct: 55 VCMAVSR 61
>XP_005266875
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   LCLAISRSS 9
           LC  +SR S
Sbjct: 388 LCFVLSRGS 396
>XP_005249232
          Length = 189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   LCLAIS 6
           LCLA+S
Sbjct: 97  LCLAVS 102
>NP_060426
          Length = 448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   LCLAISR 7
           LCL +SR
Sbjct: 107 LCLEVSR 113
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.329    0.127    0.355 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 446,416
Number of extensions: 531
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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