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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004963                                                              19     869
XP_005251512                                                           19     869
NP_004551                                                              17    4312
XP_005252066                                                           17    4312
XP_006717184                                                           17    4312
XP_005252065                                                           17    4312
NP_001238831                                                           16    5631
NP_003976                                                              16    5631
NP_113641                                                              16    7355
NP_079169                                                              16    7355
NP_001129980                                                           16    7355
XP_006723691                                                           16    7355
XP_006723690                                                           16    7355
XP_006723689                                                           16    7355
XP_005270828                                                           16    7355
NP_005493                                                              15    9605
NP_001258358                                                           15    9605
NP_001258357                                                           15    9605
NP_055862                                                              15    9605
NP_001258356                                                           15    9605
XP_005251837                                                           15    9605
XP_005251835                                                           15    9605
XP_006717058                                                           15    9605
XP_005251833                                                           15    9605
XP_005251831                                                           15    9605
XP_005251830                                                           15    9605
XP_005245845                                                           15    9605
XP_005245844                                                           15    9605

>NP_004963
          Length = 1132

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LATRNILAE 9
           LATRNIL E
Sbjct: 977 LATRNILVE 985



>XP_005251512
          Length = 1132

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   LATRNILAE 9
           LATRNIL E
Sbjct: 977 LATRNILVE 985



>NP_004551
          Length = 943

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LATRNIL 7
           LATRN+L
Sbjct: 616 LATRNVL 622



>XP_005252066
          Length = 542

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LATRNIL 7
           LATRN+L
Sbjct: 215 LATRNVL 221



>XP_006717184
          Length = 803

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LATRNIL 7
           LATRN+L
Sbjct: 476 LATRNVL 482



>XP_005252065
          Length = 803

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LATRNIL 7
           LATRN+L
Sbjct: 476 LATRNVL 482



>NP_001238831
          Length = 666

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LATRNIL 7
           LATRN+L
Sbjct: 246 LATRNLL 252



>NP_003976
          Length = 661

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LATRNIL 7
           LATRN+L
Sbjct: 246 LATRNLL 252



>NP_113641
          Length = 306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LATRNILAE 9
           L TR+I+AE
Sbjct: 170 LITRSIMAE 178



>NP_079169
          Length = 258

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  TRNILAE 9
          TRN++AE
Sbjct: 28 TRNLMAE 34



>NP_001129980
          Length = 199

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LATRNILAE 9
           LAT+NI+ +
Sbjct: 110 LATKNIICD 118



>XP_006723691
          Length = 256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  TRNILAE 9
          TRN++AE
Sbjct: 28 TRNLMAE 34



>XP_006723690
          Length = 258

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  TRNILAE 9
          TRN++AE
Sbjct: 28 TRNLMAE 34



>XP_006723689
          Length = 258

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  TRNILAE 9
          TRN++AE
Sbjct: 28 TRNLMAE 34



>XP_005270828
          Length = 444

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   LATRNILAE 9
           LAT+NI+ +
Sbjct: 355 LATKNIICD 363



>NP_005493
          Length = 2261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ATRNILAE 9
           ATR ++AE
Sbjct: 391 ATRQVMAE 398



>NP_001258358
          Length = 971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ATRNILAE 9
           ATRN+L +
Sbjct: 632 ATRNVLRQ 639



>NP_001258357
          Length = 992

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ATRNILAE 9
           ATRN+L +
Sbjct: 653 ATRNVLRQ 660



>NP_055862
          Length = 993

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ATRNILAE 9
           ATRN+L +
Sbjct: 654 ATRNVLRQ 661



>NP_001258356
          Length = 992

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ATRNILAE 9
           ATRN+L +
Sbjct: 653 ATRNVLRQ 660



>XP_005251837
          Length = 1659

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ATRNILAE 9
           ATR ++AE
Sbjct: 391 ATRQVMAE 398



>XP_005251835
          Length = 2074

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ATRNILAE 9
           ATR ++AE
Sbjct: 391 ATRQVMAE 398



>XP_006717058
          Length = 2100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ATRNILAE 9
           ATR ++AE
Sbjct: 391 ATRQVMAE 398



>XP_005251833
          Length = 2203

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ATRNILAE 9
           ATR ++AE
Sbjct: 331 ATRQVMAE 338



>XP_005251831
          Length = 2263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ATRNILAE 9
           ATR ++AE
Sbjct: 391 ATRQVMAE 398



>XP_005251830
          Length = 2263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ATRNILAE 9
           ATR ++AE
Sbjct: 391 ATRQVMAE 398



>XP_005245845
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ATRNILAE 9
           ATRN+L +
Sbjct: 656 ATRNVLRQ 663



>XP_005245844
          Length = 996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ATRNILAE 9
           ATRN+L +
Sbjct: 657 ATRNVLRQ 664



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.130    0.314 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 296,227
Number of extensions: 487
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)