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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001138498                                                           17    4312
NP_004275                                                              16    5631
NP_612152                                                              16    5631
NP_005348                                                              16    5631
XP_005258998                                                           16    5631
XP_006723281                                                           16    5631
XP_005258997                                                           16    5631
XP_005258996                                                           16    5631
XP_005258995                                                           16    5631
XP_006715715                                                           16    5631
XP_006711701                                                           16    5631
XP_006711700                                                           16    5631
XP_006711699                                                           16    5631
NP_787954                                                              16    7355
NP_059130                                                              16    7355
NP_001275891                                                           16    7355
XP_005276355                                                           16    7355
XP_006723003                                                           16    7355
XP_005254520                                                           16    7355
XP_005250801                                                           16    7355
XP_005276060                                                           16    7355
NP_597677                                                              15    9605
NP_056199                                                              15    9605
NP_620636                                                              15    9605
NP_003062                                                              15    9605
NP_061956                                                              15    9605
NP_061830                                                              15    9605
XP_005248340                                                           15    9605
XP_005248339                                                           15    9605
XP_005248337                                                           15    9605
XP_006714531                                                           15    9605
XP_006714530                                                           15    9605
XP_005247781                                                           15    9605
XP_005271002                                                           15    9605
NP_001128129                                                           15    9605

>NP_001138498
          Length = 2299

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   APLSILSE 9
           AP+SIL+E
Sbjct: 843 APISILTE 850



>NP_004275
          Length = 897

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LAPLSILS 8
           L PLS+LS
Sbjct: 101 LCPLSVLS 108



>NP_612152
          Length = 2849

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   APLSILSE 9
           AP+S++SE
Sbjct: 779 APVSVISE 786



>NP_005348
          Length = 1076

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LAPLSILSE 9
           L PLS+LS+
Sbjct: 774 LLPLSVLSK 782



>XP_005258998
          Length = 775

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LAPLSILSE 9
           L PLS+LS+
Sbjct: 473 LLPLSVLSK 481



>XP_006723281
          Length = 775

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LAPLSILSE 9
           L PLS+LS+
Sbjct: 473 LLPLSVLSK 481



>XP_005258997
          Length = 775

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LAPLSILSE 9
           L PLS+LS+
Sbjct: 473 LLPLSVLSK 481



>XP_005258996
          Length = 786

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LAPLSILSE 9
           L PLS+LS+
Sbjct: 484 LLPLSVLSK 492



>XP_005258995
          Length = 821

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LAPLSILSE 9
           L PLS+LS+
Sbjct: 519 LLPLSVLSK 527



>XP_006715715
          Length = 2023

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   APLSILSE 9
           AP+S++SE
Sbjct: 731 APVSVISE 738



>XP_006711701
          Length = 792

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LAPLSILS 8
           L PLS+LS
Sbjct: 101 LCPLSVLS 108



>XP_006711700
          Length = 803

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LAPLSILS 8
           L PLS+LS
Sbjct: 101 LCPLSVLS 108



>XP_006711699
          Length = 825

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  LAPLSILS 8
          L PLS+LS
Sbjct: 29 LCPLSVLS 36



>NP_787954
          Length = 1551

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    LAPLSILS 8
            ++PLS+LS
Sbjct: 1157 ISPLSVLS 1164



>NP_059130
          Length = 1551

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    LAPLSILS 8
            ++PLS+LS
Sbjct: 1157 ISPLSVLS 1164



>NP_001275891
          Length = 601

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PLSILSE 9
           PL+ILSE
Sbjct: 358 PLAILSE 364



>XP_005276355
          Length = 233

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LAPLSILS 8
           L+PL+ILS
Sbjct: 183 LSPLAILS 190



>XP_006723003
          Length = 649

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PLSILSE 9
           PL+ILSE
Sbjct: 358 PLAILSE 364



>XP_005254520
          Length = 1235

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   LAPLSILS 8
           ++PLS+LS
Sbjct: 841 ISPLSVLS 848



>XP_005250801
          Length = 233

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LAPLSILS 8
           L+PL+ILS
Sbjct: 183 LSPLAILS 190



>XP_005276060
          Length = 233

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LAPLSILS 8
           L+PL+ILS
Sbjct: 183 LSPLAILS 190



>NP_597677
          Length = 2804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   APLSILSE 9
           AP+S+L E
Sbjct: 576 APVSVLQE 583



>NP_056199
          Length = 2697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   APLSILSE 9
           AP+S+L E
Sbjct: 576 APVSVLQE 583



>NP_620636
          Length = 1009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LAPLSILS 8
           + PLS+LS
Sbjct: 481 ICPLSVLS 488



>NP_003062
          Length = 1009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LAPLSILS 8
           + PLS+LS
Sbjct: 481 ICPLSVLS 488



>NP_061956
          Length = 481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LAPLSILSE 9
           L P+S LSE
Sbjct: 108 LVPISSLSE 116



>NP_061830
          Length = 701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LAPLSILSE 9
           L PLS LSE
Sbjct: 124 LQPLSRLSE 132



>XP_005248340
          Length = 2265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  APLSILSE 9
          AP+S+L E
Sbjct: 37 APVSVLQE 44



>XP_005248339
          Length = 2584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   APLSILSE 9
           AP+S+L E
Sbjct: 356 APVSVLQE 363



>XP_005248337
          Length = 2698

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   APLSILSE 9
           AP+S+L E
Sbjct: 576 APVSVLQE 583



>XP_006714531
          Length = 2738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   APLSILSE 9
           AP+S+L E
Sbjct: 576 APVSVLQE 583



>XP_006714530
          Length = 2755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   APLSILSE 9
           AP+S+L E
Sbjct: 576 APVSVLQE 583



>XP_005247781
          Length = 1008

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   LAPLSILS 8
           + PLS+LS
Sbjct: 480 ICPLSVLS 487



>XP_005271002
          Length = 467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   LAPLSILSE 9
           L P+S LSE
Sbjct: 108 LVPISSLSE 116



>NP_001128129
          Length = 262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  LAPLSIL 7
          LAP+S+L
Sbjct: 82 LAPMSVL 88



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.132    0.325 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 547,064
Number of extensions: 860
Number of successful extensions: 35
Number of sequences better than 10000.0: 35
Number of HSP's gapped: 35
Number of HSP's successfully gapped: 35
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)