Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005087                                                              18    1935
NP_001164633                                                           18    1935
NP_963893                                                              18    1935
XP_005262367                                                           18    1935
XP_006724778                                                           18    1935
XP_005262366                                                           18    1935
NP_008969                                                              17    2528
NP_001272390                                                           17    3301
NP_006624                                                              17    3301
NP_001272391                                                           17    3301
NP_001272389                                                           17    3301
NP_001152794                                                           17    3301
NP_001152795                                                           17    3301
NP_003697                                                              17    3301
XP_006723514                                                           17    3301
XP_005248471                                                           17    3301
XP_005248470                                                           17    3301
XP_006714585                                                           17    3301
XP_005248468                                                           17    3301
XP_005248467                                                           17    3301
XP_005248466                                                           17    3301
NP_001189394                                                           17    4312
NP_001189393                                                           17    4312
NP_001189395                                                           17    4312
NP_001189396                                                           17    4312
NP_006161                                                              17    4312
NP_001028886                                                           17    4312
NP_001245239                                                           17    4312
NP_001245237                                                           17    4312
NP_001245238                                                           17    4312
XP_005253748                                                           17    4312
XP_005252420                                                           17    4312
XP_006717439                                                           17    4312
XP_005252419                                                           17    4312
XP_005252418                                                           17    4312
NP_060132                                                              16    5631
NP_149020                                                              16    5631
NP_001170781                                                           16    5631
NP_060862                                                              16    5631
XP_006724673                                                           16    5631
XP_006721691                                                           16    5631
XP_006717022                                                           16    5631
XP_005263172                                                           16    5631
NP_001170782                                                           16    5631
NP_006615                                                              16    7355
NP_997644                                                              16    7355
NP_001189397                                                           16    7355
NP_036363                                                              16    7355
NP_001007258                                                           16    7355
NP_056950                                                              16    7355
XP_005252417                                                           16    7355
XP_005252416                                                           16    7355
XP_005246055                                                           16    7355
XP_006710943                                                           16    7355
XP_006710942                                                           16    7355
XP_006710941                                                           16    7355
XP_005246054                                                           16    7355
XP_005246053                                                           16    7355
XP_006710940                                                           16    7355
XP_005246052                                                           16    7355
XP_005246051                                                           16    7355
XP_005246050                                                           16    7355
XP_005246049                                                           16    7355
NP_001013859                                                           15    9605
NP_001013858                                                           15    9605
NP_003541                                                              15    9605
NP_001257449                                                           15    9605
NP_055807                                                              15    9605
XP_005267488                                                           15    9605
XP_005267487                                                           15    9605
XP_005249935                                                           15    9605
XP_005249934                                                           15    9605
XP_006715851                                                           15    9605
XP_005249933                                                           15    9605
>NP_005087
          Length = 1370

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ALKKKNTR 9
           A KKKNTR
Sbjct: 487 AYKKKNTR 494
>NP_001164633
          Length = 1358

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ALKKKNTR 9
           A KKKNTR
Sbjct: 487 AYKKKNTR 494
>NP_963893
          Length = 1370

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ALKKKNTR 9
           A KKKNTR
Sbjct: 487 AYKKKNTR 494
>XP_005262367
          Length = 1358

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ALKKKNTR 9
           A KKKNTR
Sbjct: 487 AYKKKNTR 494
>XP_006724778
          Length = 1370

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ALKKKNTR 9
           A KKKNTR
Sbjct: 487 AYKKKNTR 494
>XP_005262366
          Length = 1370

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ALKKKNTR 9
           A KKKNTR
Sbjct: 487 AYKKKNTR 494
>NP_008969
          Length = 930

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   LALKKKN 7
           LALKKKN
Sbjct: 775 LALKKKN 781
>NP_001272390
          Length = 1071

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LKKKNTR 9
           LK+KNTR
Sbjct: 949 LKRKNTR 955
>NP_006624
          Length = 1575

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LKKKNTR 9
            LK+KNTR
Sbjct: 1453 LKRKNTR 1459
>NP_001272391
          Length = 1071

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LKKKNTR 9
           LK+KNTR
Sbjct: 949 LKRKNTR 955
>NP_001272389
          Length = 1525

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LKKKNTR 9
            LK+KNTR
Sbjct: 1403 LKRKNTR 1409
>NP_001152794
          Length = 551

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LALKKKNTR 9
           LAL KKN R
Sbjct: 514 LALAKKNVR 522
>NP_001152795
          Length = 527

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LALKKKNTR 9
           LAL KKN R
Sbjct: 504 LALAKKNVR 512
>NP_003697
          Length = 541

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LALKKKNTR 9
           LAL KKN R
Sbjct: 504 LALAKKNVR 512
>XP_006723514
          Length = 523

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   LALKKKNTR 9
           LAL KKN R
Sbjct: 486 LALAKKNVR 494
>XP_005248471
          Length = 1128

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LKKKNTR 9
            LK+KNTR
Sbjct: 1006 LKRKNTR 1012
>XP_005248470
          Length = 1518

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LKKKNTR 9
            LK+KNTR
Sbjct: 1396 LKRKNTR 1402
>XP_006714585
          Length = 1525

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LKKKNTR 9
            LK+KNTR
Sbjct: 1403 LKRKNTR 1409
>XP_005248468
          Length = 1548

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LKKKNTR 9
            LK+KNTR
Sbjct: 1426 LKRKNTR 1432
>XP_005248467
          Length = 1548

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LKKKNTR 9
            LK+KNTR
Sbjct: 1426 LKRKNTR 1432
>XP_005248466
          Length = 1565

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LKKKNTR 9
            LK+KNTR
Sbjct: 1443 LKRKNTR 1449
>NP_001189394
          Length = 517

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LALKKKNT 8
          +++KKKNT
Sbjct: 92 ISIKKKNT 99
>NP_001189393
          Length = 548

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LALKKKNT 8
          +++KKKNT
Sbjct: 92 ISIKKKNT 99
>NP_001189395
          Length = 547

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LALKKKNT 8
          +++KKKNT
Sbjct: 92 ISIKKKNT 99
>NP_001189396
          Length = 514

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LALKKKNT 8
          +++KKKNT
Sbjct: 92 ISIKKKNT 99
>NP_006161
          Length = 808

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ALKKKNTR 9
           ALKK+N R
Sbjct: 527 ALKKRNVR 534
>NP_001028886
          Length = 808

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ALKKKNTR 9
           ALKK+N R
Sbjct: 527 ALKKRNVR 534
>NP_001245239
          Length = 628

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ALKKKNTR 9
           ALKK+N R
Sbjct: 527 ALKKRNVR 534
>NP_001245237
          Length = 812

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ALKKKNTR 9
           ALKK+N R
Sbjct: 531 ALKKRNVR 538
>NP_001245238
          Length = 845

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ALKKKNTR 9
           ALKK+N R
Sbjct: 564 ALKKRNVR 571
>XP_005253748
          Length = 812

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ALKKKNTR 9
           ALKK+N R
Sbjct: 531 ALKKRNVR 538
>XP_005252420
          Length = 547

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LALKKKNT 8
          +++KKKNT
Sbjct: 92 ISIKKKNT 99
>XP_006717439
          Length = 548

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LALKKKNT 8
          +++KKKNT
Sbjct: 92 ISIKKKNT 99
>XP_005252419
          Length = 548

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LALKKKNT 8
          +++KKKNT
Sbjct: 92 ISIKKKNT 99
>XP_005252418
          Length = 548

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  LALKKKNT 8
          +++KKKNT
Sbjct: 92 ISIKKKNT 99
>NP_060132
          Length = 2022

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LALKKKNTR 9
            L+ KKKNT+
Sbjct: 1582 LSKKKKNTQ 1590
>NP_149020
          Length = 1395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LALKKKNT 8
           L+LKKK+T
Sbjct: 747 LSLKKKST 754
>NP_001170781
          Length = 2017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LALKKKNTR 9
            L+ KKKNT+
Sbjct: 1577 LSKKKKNTQ 1585
>NP_060862
          Length = 2104

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LKKKNT 8
           LKKKNT
Sbjct: 845 LKKKNT 850
>XP_006724673
          Length = 1396

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   LALKKKNT 8
           L+LKKK+T
Sbjct: 747 LSLKKKST 754
>XP_006721691
          Length = 496

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LALKKKNTR 9
           LALKK+N +
Sbjct: 344 LALKKENVQ 352
>XP_006717022
          Length = 1054

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   LALKKKNTR 9
           L+ KKKNT+
Sbjct: 614 LSKKKKNTQ 622
>XP_005263172
          Length = 2104

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LKKKNT 8
           LKKKNT
Sbjct: 845 LKKKNT 850
>NP_001170782
          Length = 2017

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    LALKKKNTR 9
            L+ KKKNT+
Sbjct: 1577 LSKKKKNTQ 1585
>NP_006615
          Length = 602

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ALKKKNT 8
           ++KKKNT
Sbjct: 147 SIKKKNT 153
>NP_997644
          Length = 567

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ALKKKNT 8
           ++KKKNT
Sbjct: 147 SIKKKNT 153
>NP_001189397
          Length = 568

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ALKKKNT 8
           ++KKKNT
Sbjct: 147 SIKKKNT 153
>NP_036363
          Length = 1718

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ALKKKN 7
            ALKKKN
Sbjct: 1421 ALKKKN 1426
>NP_001007258
          Length = 1481

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ALKKKN 7
            ALKKKN
Sbjct: 1220 ALKKKN 1225
>NP_056950
          Length = 1682

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ALKKKN 7
            ALKKKN
Sbjct: 1421 ALKKKN 1426
>XP_005252417
          Length = 601

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ALKKKNT 8
           ++KKKNT
Sbjct: 147 SIKKKNT 153
>XP_005252416
          Length = 602

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ALKKKNT 8
           ++KKKNT
Sbjct: 147 SIKKKNT 153
>XP_005246055
          Length = 1481

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ALKKKN 7
            ALKKKN
Sbjct: 1220 ALKKKN 1225
>XP_006710943
          Length = 1517

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ALKKKN 7
            ALKKKN
Sbjct: 1220 ALKKKN 1225
>XP_006710942
          Length = 1517

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ALKKKN 7
            ALKKKN
Sbjct: 1220 ALKKKN 1225
>XP_006710941
          Length = 1517

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ALKKKN 7
            ALKKKN
Sbjct: 1220 ALKKKN 1225
>XP_005246054
          Length = 1517

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ALKKKN 7
            ALKKKN
Sbjct: 1220 ALKKKN 1225
>XP_005246053
          Length = 1644

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ALKKKN 7
            ALKKKN
Sbjct: 1347 ALKKKN 1352
>XP_006710940
          Length = 1682

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ALKKKN 7
            ALKKKN
Sbjct: 1421 ALKKKN 1426
>XP_005246052
          Length = 1692

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ALKKKN 7
            ALKKKN
Sbjct: 1431 ALKKKN 1436
>XP_005246051
          Length = 1717

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ALKKKN 7
            ALKKKN
Sbjct: 1420 ALKKKN 1425
>XP_005246050
          Length = 1718

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ALKKKN 7
            ALKKKN
Sbjct: 1421 ALKKKN 1426
>XP_005246049
          Length = 1728

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ALKKKN 7
            ALKKKN
Sbjct: 1431 ALKKKN 1436
>NP_001013859
          Length = 718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LALKKKNT 8
           LALK KN+
Sbjct: 346 LALKDKNS 353
>NP_001013858
          Length = 718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LALKKKNT 8
           LALK KN+
Sbjct: 346 LALKDKNS 353
>NP_003541
          Length = 718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LALKKKNT 8
           LALK KN+
Sbjct: 346 LALKDKNS 353
>NP_001257449
          Length = 1068

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LALKKKN 7
           LALKKK+
Sbjct: 596 LALKKKS 602
>NP_055807
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LALKKKN 7
           LALKKK+
Sbjct: 596 LALKKKS 602
>XP_005267488
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LALKKKN 7
           LALKKK+
Sbjct: 596 LALKKKS 602
>XP_005267487
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   LALKKKN 7
           LALKKK+
Sbjct: 596 LALKKKS 602
>XP_005249935
          Length = 671

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LALKKKNT 8
           LALK KN+
Sbjct: 299 LALKDKNS 306
>XP_005249934
          Length = 671

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LALKKKNT 8
           LALK KN+
Sbjct: 299 LALKDKNS 306
>XP_006715851
          Length = 718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LALKKKNT 8
           LALK KN+
Sbjct: 346 LALKDKNS 353
>XP_005249933
          Length = 718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   LALKKKNT 8
           LALK KN+
Sbjct: 346 LALKDKNS 353
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.123    0.301 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 550,065
Number of extensions: 916
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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