Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              19     869
XP_006718908                                                           19     869
XP_005271621                                                           19     869
XP_006718907                                                           19     869
XP_006718906                                                           19     869
XP_005271619                                                           19     869
XP_005271618                                                           19     869
NP_659475                                                              15    9605
NP_942133                                                              15    9605
NP_942131                                                              15    9605
NP_942134                                                              15    9605
NP_942135                                                              15    9605
NP_942136                                                              15    9605
NP_001119576                                                           15    9605
NP_037409                                                              15    9605
NP_001119575                                                           15    9605
NP_055646                                                              15    9605
XP_006725384                                                           15    9605
XP_006725383                                                           15    9605
XP_005257324                                                           15    9605
XP_005257323                                                           15    9605
XP_006721916                                                           15    9605
XP_006719423                                                           15    9605
XP_006719422                                                           15    9605
XP_005268873                                                           15    9605
XP_005268872                                                           15    9605
XP_005268870                                                           15    9605
XP_005268871                                                           15    9605
XP_005268869                                                           15    9605
XP_005268868                                                           15    9605
XP_006713495                                                           15    9605
XP_005264695                                                           15    9605
XP_005264694                                                           15    9605
>NP_000042
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KVVERVLMR 9
            KV ERVLMR
Sbjct: 3004 KVAERVLMR 3012
>XP_006718908
          Length = 1708

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KVVERVLMR 9
            KV ERVLMR
Sbjct: 1656 KVAERVLMR 1664
>XP_005271621
          Length = 2708

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KVVERVLMR 9
            KV ERVLMR
Sbjct: 2656 KVAERVLMR 2664
>XP_006718907
          Length = 3050

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KVVERVLMR 9
            KV ERVLMR
Sbjct: 2998 KVAERVLMR 3006
>XP_006718906
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KVVERVLMR 9
            KV ERVLMR
Sbjct: 3004 KVAERVLMR 3012
>XP_005271619
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KVVERVLMR 9
            KV ERVLMR
Sbjct: 3004 KVAERVLMR 3012
>XP_005271618
          Length = 3056

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KVVERVLMR 9
            KV ERVLMR
Sbjct: 3004 KVAERVLMR 3012
>NP_659475
          Length = 740

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVVERVLMR 9
           ++VE +LMR
Sbjct: 456 QIVEEMLMR 464
>NP_942133
          Length = 2346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVVERVLM 8
           KV+E+VL+
Sbjct: 116 KVIEKVLI 123
>NP_942131
          Length = 2383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVVERVLM 8
           KV+E+VL+
Sbjct: 153 KVIEKVLI 160
>NP_942134
          Length = 2288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  KVVERVLM 8
          KV+E+VL+
Sbjct: 58 KVIEKVLI 65
>NP_942135
          Length = 2268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  KVVERVLM 8
          KV+E+VL+
Sbjct: 38 KVIEKVLI 45
>NP_942136
          Length = 2346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVVERVLM 8
           KV+E+VL+
Sbjct: 116 KVIEKVLI 123
>NP_001119576
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KVVERVL 7
           KVVER+L
Sbjct: 526 KVVERLL 532
>NP_037409
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KVVERVL 7
           KVVER+L
Sbjct: 526 KVVERLL 532
>NP_001119575
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KVVERVL 7
           KVVER+L
Sbjct: 526 KVVERLL 532
>NP_055646
          Length = 2925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    KVVERVLM 8
            KVV+RVL+
Sbjct: 2569 KVVKRVLV 2576
>XP_006725384
          Length = 2268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  KVVERVLM 8
          KV+E+VL+
Sbjct: 38 KVIEKVLI 45
>XP_006725383
          Length = 2338

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVVERVLM 8
           KV+E+VL+
Sbjct: 116 KVIEKVLI 123
>XP_005257324
          Length = 2268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  KVVERVLM 8
          KV+E+VL+
Sbjct: 38 KVIEKVLI 45
>XP_005257323
          Length = 2268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  KVVERVLM 8
          KV+E+VL+
Sbjct: 38 KVIEKVLI 45
>XP_006721916
          Length = 2375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVVERVLM 8
           KV+E+VL+
Sbjct: 153 KVIEKVLI 160
>XP_006719423
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KVVERVL 7
           KVVER+L
Sbjct: 526 KVVERLL 532
>XP_006719422
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KVVERVL 7
           KVVER+L
Sbjct: 526 KVVERLL 532
>XP_005268873
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KVVERVL 7
           KVVER+L
Sbjct: 526 KVVERLL 532
>XP_005268872
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KVVERVL 7
           KVVER+L
Sbjct: 526 KVVERLL 532
>XP_005268870
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KVVERVL 7
           KVVER+L
Sbjct: 526 KVVERLL 532
>XP_005268871
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KVVERVL 7
           KVVER+L
Sbjct: 526 KVVERLL 532
>XP_005268869
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KVVERVL 7
           KVVER+L
Sbjct: 526 KVVERLL 532
>XP_005268868
          Length = 651

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KVVERVL 7
           KVVER+L
Sbjct: 545 KVVERLL 551
>XP_006713495
          Length = 2969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    KVVERVLM 8
            KVV+RVL+
Sbjct: 2613 KVVKRVLV 2620
>XP_005264695
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVVERVLMR 9
           ++VE +LMR
Sbjct: 116 QIVEEMLMR 124
>XP_005264694
          Length = 534

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVVERVLMR 9
           ++VE +LMR
Sbjct: 250 QIVEEMLMR 258
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.339    0.146    0.354 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 308,639
Number of extensions: 383
Number of successful extensions: 33
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 33
Number of HSP's successfully gapped: 33
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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