Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              20     390
XP_006714104                                                           20     390
XP_005265800                                                           20     390
XP_006714103                                                           20     390
XP_006714102                                                           20     390
NP_003405                                                              16    5631
NP_001252517                                                           16    5631
XP_005257356                                                           16    7355
NP_001264243                                                           15    9605
NP_002559                                                              15    9605
NP_060546                                                              15    9605
NP_001276949                                                           15    9605
NP_001248375                                                           15    9605
NP_001248374                                                           15    9605
NP_877420                                                              15    9605
NP_001087240                                                           15    9605
NP_055462                                                              15    9605
NP_001171928                                                           15    9605
NP_001129126                                                           15    9605
NP_001129125                                                           15    9605
NP_001264242                                                           15    9605
NP_001171927                                                           15    9605
NP_003810                                                              15    9605
NP_877393                                                              15    9605
NP_877419                                                              15    9605
NP_003321                                                              15    9605
XP_005276481                                                           15    9605
XP_006726576                                                           15    9605
XP_006725284                                                           15    9605
XP_006725283                                                           15    9605
XP_006725282                                                           15    9605
XP_006725281                                                           15    9605
XP_006725280                                                           15    9605
XP_006725279                                                           15    9605
XP_006725278                                                           15    9605
XP_005256085                                                           15    9605
XP_005256083                                                           15    9605
XP_005255766                                                           15    9605
XP_006721049                                                           15    9605
XP_005255765                                                           15    9605
XP_005255764                                                           15    9605
XP_005255763                                                           15    9605
XP_005255762                                                           15    9605
XP_005255761                                                           15    9605
XP_005269323                                                           15    9605
XP_006717607                                                           15    9605
XP_005252542                                                           15    9605
XP_006717518                                                           15    9605
XP_006717517                                                           15    9605
XP_006717516                                                           15    9605
XP_005250918                                                           15    9605
XP_005275780                                                           15    9605
XP_006709998                                                           15    9605
NP_060766                                                              15    9605
NP_001155047                                                           15    9605
NP_112241                                                              15    9605
>NP_006197
          Length = 1089

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KVEETVAVR 9
           KVEET+AVR
Sbjct: 492 KVEETIAVR 500
>XP_006714104
          Length = 832

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KVEETVAVR 9
           KVEET+AVR
Sbjct: 517 KVEETIAVR 525
>XP_005265800
          Length = 1089

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KVEETVAVR 9
           KVEET+AVR
Sbjct: 492 KVEETIAVR 500
>XP_006714103
          Length = 1111

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KVEETVAVR 9
           KVEET+AVR
Sbjct: 514 KVEETIAVR 522
>XP_006714102
          Length = 1114

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KVEETVAVR 9
           KVEET+AVR
Sbjct: 517 KVEETIAVR 525
>NP_003405
          Length = 743

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KVEETVAVR 9
          K EETVA++
Sbjct: 66 KSEETVAIQ 74
>NP_001252517
          Length = 711

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KVEETVAVR 9
          K EETVA++
Sbjct: 34 KSEETVAIQ 42
>XP_005257356
          Length = 598

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KVEETVAV 8
           K EETVA+
Sbjct: 452 KKEETVAI 459
>NP_001264243
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVEETVAVR 9
           K +ET+A+R
Sbjct: 349 KGKETIAIR 357
>NP_002559
          Length = 636

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KVEETVAV 8
           KV+E VAV
Sbjct: 606 KVDEAVAV 613
>NP_060546
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KVEETVA 7
           K+EETV+
Sbjct: 418 KIEETVS 424
>NP_001276949
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KVEETVA 7
           K+EETV+
Sbjct: 418 KIEETVS 424
>NP_001248375
          Length = 461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  KVEETV 6
          KVEETV
Sbjct: 51 KVEETV 56
>NP_001248374
          Length = 549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KVEETV 6
           KVEETV
Sbjct: 139 KVEETV 144
>NP_877420
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  KVEETV 6
          KVEETV
Sbjct: 89 KVEETV 94
>NP_001087240
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KVEETV 6
           KVEETV
Sbjct: 239 KVEETV 244
>NP_055462
          Length = 1742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVEETVAVR 9
           K+ +TVA+R
Sbjct: 919 KLTDTVAIR 927
>NP_001171928
          Length = 1739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVEETVAVR 9
           K+ +TVA+R
Sbjct: 916 KLTDTVAIR 924
>NP_001129126
          Length = 631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KVEETVAV 8
           KV+E VAV
Sbjct: 602 KVDEAVAV 609
>NP_001129125
          Length = 660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KVEETVAV 8
           KV+E VAV
Sbjct: 631 KVDEAVAV 638
>NP_001264242
          Length = 1419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVEETVAVR 9
           K +ET+A+R
Sbjct: 349 KGKETIAIR 357
>NP_001171927
          Length = 1742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVEETVAVR 9
           K+ +TVA+R
Sbjct: 919 KLTDTVAIR 927
>NP_003810
          Length = 644

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KVEETVAV 8
           KV+E VAV
Sbjct: 615 KVDEAVAV 622
>NP_877393
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  KVEETV 6
          KVEETV
Sbjct: 89 KVEETV 94
>NP_877419
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  KVEETV 6
          KVEETV
Sbjct: 89 KVEETV 94
>NP_003321
          Length = 551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KVEETV 6
           KVEETV
Sbjct: 141 KVEETV 146
>XP_005276481
          Length = 160

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KVEETVAV 8
           KV+E VAV
Sbjct: 131 KVDEAVAV 138
>XP_006726576
          Length = 213

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KVEETVA 7
           K+EETV+
Sbjct: 136 KIEETVS 142
>XP_006725284
          Length = 1564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVEETVAVR 9
           K+ +TVA+R
Sbjct: 741 KLTDTVAIR 749
>XP_006725283
          Length = 1600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVEETVAVR 9
           K+ +TVA+R
Sbjct: 777 KLTDTVAIR 785
>XP_006725282
          Length = 1613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVEETVAVR 9
           K+ +TVA+R
Sbjct: 790 KLTDTVAIR 798
>XP_006725281
          Length = 1733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVEETVAVR 9
           K+ +TVA+R
Sbjct: 910 KLTDTVAIR 918
>XP_006725280
          Length = 1741

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVEETVAVR 9
           K+ +TVA+R
Sbjct: 918 KLTDTVAIR 926
>XP_006725279
          Length = 1743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVEETVAVR 9
           K+ +TVA+R
Sbjct: 920 KLTDTVAIR 928
>XP_006725278
          Length = 1743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVEETVAVR 9
           K+ +TVA+R
Sbjct: 920 KLTDTVAIR 928
>XP_005256085
          Length = 586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVEETVAV 8
           K+E+TVA+
Sbjct: 501 KLEKTVAI 508
>XP_005256083
          Length = 607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVEETVAV 8
           K+E+TVA+
Sbjct: 522 KLEKTVAI 529
>XP_005255766
          Length = 1564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVEETVAVR 9
           K+ +TVA+R
Sbjct: 741 KLTDTVAIR 749
>XP_006721049
          Length = 1600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVEETVAVR 9
           K+ +TVA+R
Sbjct: 777 KLTDTVAIR 785
>XP_005255765
          Length = 1613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVEETVAVR 9
           K+ +TVA+R
Sbjct: 790 KLTDTVAIR 798
>XP_005255764
          Length = 1733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVEETVAVR 9
           K+ +TVA+R
Sbjct: 910 KLTDTVAIR 918
>XP_005255763
          Length = 1741

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVEETVAVR 9
           K+ +TVA+R
Sbjct: 918 KLTDTVAIR 926
>XP_005255762
          Length = 1743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVEETVAVR 9
           K+ +TVA+R
Sbjct: 920 KLTDTVAIR 928
>XP_005255761
          Length = 1743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KVEETVAVR 9
           K+ +TVA+R
Sbjct: 920 KLTDTVAIR 928
>XP_005269323
          Length = 160

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KVEETVAV 8
           KV+E VAV
Sbjct: 131 KVDEAVAV 138
>XP_006717607
          Length = 213

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KVEETVA 7
           K+EETV+
Sbjct: 136 KIEETVS 142
>XP_005252542
          Length = 736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KVEETVA 7
           K+EETV+
Sbjct: 110 KIEETVS 116
>XP_006717518
          Length = 736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KVEETVA 7
           K+EETV+
Sbjct: 110 KIEETVS 116
>XP_006717517
          Length = 927

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KVEETVA 7
           K+EETV+
Sbjct: 301 KIEETVS 307
>XP_006717516
          Length = 1012

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KVEETVA 7
           K+EETV+
Sbjct: 386 KIEETVS 392
>XP_005250918
          Length = 636

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KVEETVAV 8
           KV+E VAV
Sbjct: 606 KVDEAVAV 613
>XP_005275780
          Length = 160

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KVEETVAV 8
           KV+E VAV
Sbjct: 131 KVDEAVAV 138
>XP_006709998
          Length = 187

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  KVEETVA 7
          K+EETV+
Sbjct: 80 KIEETVS 86
>NP_060766
          Length = 754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVEETVAV 8
           K+E+TVA+
Sbjct: 669 KLEKTVAI 676
>NP_001155047
          Length = 633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVEETVAV 8
           K+E+TVA+
Sbjct: 548 KLEKTVAI 555
>NP_112241
          Length = 631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KVEETVAV 8
           KV+E VAV
Sbjct: 601 KVDEAVAV 608
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.307    0.120    0.274 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 397,487
Number of extensions: 352
Number of successful extensions: 56
Number of sequences better than 10000.0: 56
Number of HSP's gapped: 56
Number of HSP's successfully gapped: 56
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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