Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              19     869
XP_006714104                                                           19     869
XP_005265800                                                           19     869
XP_006714103                                                           19     869
XP_006714102                                                           19     869
NP_001157871                                                           17    4312
NP_000713                                                              16    5631
XP_006716184                                                           16    5631
XP_006716183                                                           16    5631
XP_005250631                                                           16    5631
XP_005250630                                                           16    5631
XP_006716182                                                           16    5631
XP_005250629                                                           16    5631
XP_005250627                                                           16    5631
XP_006716181                                                           16    5631
NP_852478                                                              16    7355
XP_005247181                                                           16    7355
NP_001862                                                              16    7355
NP_036374                                                              15    9605
NP_001154819                                                           15    9605
NP_001154817                                                           15    9605
NP_060693                                                              15    9605
NP_001154818                                                           15    9605
NP_001154816                                                           15    9605
NP_001138985                                                           15    9605
NP_055581                                                              15    9605
NP_001020029                                                           15    9605
NP_001661                                                              15    9605
NP_005779                                                              15    9605
NP_963848                                                              15    9605
NP_001336                                                              15    9605
NP_958852                                                              15    9605
NP_001138987                                                           15    9605
NP_001138986                                                           15    9605
NP_001138639                                                           15    9605
NP_001138638                                                           15    9605
NP_000338                                                              15    9605
NP_079113                                                              15    9605
XP_006724314                                                           15    9605
XP_006724313                                                           15    9605
XP_006724312                                                           15    9605
XP_006724311                                                           15    9605
XP_006724310                                                           15    9605
XP_006724309                                                           15    9605
XP_005261301                                                           15    9605
XP_006724308                                                           15    9605
XP_005261300                                                           15    9605
XP_006724307                                                           15    9605
XP_005261299                                                           15    9605
XP_006724306                                                           15    9605
XP_006720757                                                           15    9605
XP_006720756                                                           15    9605
XP_006720304                                                           15    9605
XP_005268080                                                           15    9605
XP_005267567                                                           15    9605
XP_005268747                                                           15    9605
XP_005268746                                                           15    9605
XP_005268745                                                           15    9605
XP_006718184                                                           15    9605
XP_005252787                                                           15    9605
XP_005270205                                                           15    9605
XP_005249975                                                           15    9605
NP_054764                                                              15    9605
NP_002207                                                              15    9605
NP_076950                                                              15    9605
NP_958853                                                              15    9605
>NP_006197
          Length = 1089

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVEETITVR 9
           KVEETI VR
Sbjct: 492 KVEETIAVR 500
>XP_006714104
          Length = 832

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVEETITVR 9
           KVEETI VR
Sbjct: 517 KVEETIAVR 525
>XP_005265800
          Length = 1089

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVEETITVR 9
           KVEETI VR
Sbjct: 492 KVEETIAVR 500
>XP_006714103
          Length = 1111

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVEETITVR 9
           KVEETI VR
Sbjct: 514 KVEETIAVR 522
>XP_006714102
          Length = 1114

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KVEETITVR 9
           KVEETI VR
Sbjct: 517 KVEETIAVR 525
>NP_001157871
          Length = 793

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVEETITV 8
           K++ET+TV
Sbjct: 271 KIKETVTV 278
>NP_000713
          Length = 1091

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KVEETIT 7
           K+EETIT
Sbjct: 615 KLEETIT 621
>XP_006716184
          Length = 580

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KVEETIT 7
           K+EETIT
Sbjct: 104 KLEETIT 110
>XP_006716183
          Length = 1071

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KVEETIT 7
           K+EETIT
Sbjct: 595 KLEETIT 601
>XP_005250631
          Length = 1079

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KVEETIT 7
           K+EETIT
Sbjct: 610 KLEETIT 616
>XP_005250630
          Length = 1084

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KVEETIT 7
           K+EETIT
Sbjct: 615 KLEETIT 621
>XP_006716182
          Length = 1085

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KVEETIT 7
           K+EETIT
Sbjct: 609 KLEETIT 615
>XP_005250629
          Length = 1086

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KVEETIT 7
           K+EETIT
Sbjct: 610 KLEETIT 616
>XP_005250627
          Length = 1103

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KVEETIT 7
           K+EETIT
Sbjct: 634 KLEETIT 640
>XP_006716181
          Length = 1110

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KVEETIT 7
           K+EETIT
Sbjct: 634 KLEETIT 640
>NP_852478
          Length = 1179

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KVEETITVR 9
           KV+  ITVR
Sbjct: 744 KVQRNITVR 752
>XP_005247181
          Length = 417

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  KVEETITV 8
          K E+T+TV
Sbjct: 72 KAEDTVTV 79
>NP_001862
          Length = 417

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  KVEETITV 8
          K E+T+TV
Sbjct: 72 KAEDTVTV 79
>NP_036374
          Length = 266

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KVEETIT 7
           ++EETIT
Sbjct: 149 EIEETIT 155
>NP_001154819
          Length = 572

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KVEETIT 7
           K+EET+T
Sbjct: 205 KMEETLT 211
>NP_001154817
          Length = 663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KVEETIT 7
           K+EET+T
Sbjct: 297 KMEETLT 303
>NP_060693
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KVEETIT 7
           K+EET+T
Sbjct: 256 KMEETLT 262
>NP_001154818
          Length = 652

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KVEETIT 7
           K+EET+T
Sbjct: 285 KMEETLT 291
>NP_001154816
          Length = 664

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KVEETIT 7
           K+EET+T
Sbjct: 297 KMEETLT 303
>NP_001138985
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KVEETITVR 9
           K EE+ITV+
Sbjct: 244 KQEESITVQ 252
>NP_055581
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KVEETITVR 9
           K EE+ITV+
Sbjct: 244 KQEESITVQ 252
>NP_001020029
          Length = 2328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VEETITV 8
           +E+TITV
Sbjct: 318 IEQTITV 324
>NP_001661
          Length = 962

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VEETITV 8
          +EET+TV
Sbjct: 90 LEETVTV 96
>NP_005779
          Length = 531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVEETITV 8
           K+E+TIT+
Sbjct: 301 KLEDTITL 308
>NP_963848
          Length = 735

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVEETITV 8
           K+EE++TV
Sbjct: 573 KLEESLTV 580
>NP_001336
          Length = 735

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVEETITV 8
           K+EE++TV
Sbjct: 573 KLEESLTV 580
>NP_958852
          Length = 735

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVEETITV 8
           K+EE++TV
Sbjct: 573 KLEESLTV 580
>NP_001138987
          Length = 346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KVEETITVR 9
           K EE+ITV+
Sbjct: 176 KQEESITVQ 184
>NP_001138986
          Length = 434

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KVEETITVR 9
           K EE+ITV+
Sbjct: 264 KQEESITVQ 272
>NP_001138639
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVEETITV 8
           K+E+TIT+
Sbjct: 224 KLEDTITL 231
>NP_001138638
          Length = 469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVEETITV 8
           K+E+TIT+
Sbjct: 239 KLEDTITL 246
>NP_000338
          Length = 2137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VEETITV 8
           +E+TITV
Sbjct: 318 IEQTITV 324
>NP_079113
          Length = 1192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   VEETIT 7
           VEETIT
Sbjct: 746 VEETIT 751
>XP_006724314
          Length = 656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VEETITV 8
          +EET+TV
Sbjct: 90 LEETVTV 96
>XP_006724313
          Length = 661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VEETITV 8
          +EET+TV
Sbjct: 90 LEETVTV 96
>XP_006724312
          Length = 667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VEETITV 8
          +EET+TV
Sbjct: 90 LEETVTV 96
>XP_006724311
          Length = 893

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VEETITV 8
          +EET+TV
Sbjct: 27 LEETVTV 33
>XP_006724310
          Length = 899

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VEETITV 8
          +EET+TV
Sbjct: 27 LEETVTV 33
>XP_006724309
          Length = 922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VEETITV 8
          +EET+TV
Sbjct: 8  LEETVTV 14
>XP_005261301
          Length = 929

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VEETITV 8
          +EET+TV
Sbjct: 90 LEETVTV 96
>XP_006724308
          Length = 935

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VEETITV 8
          +EET+TV
Sbjct: 90 LEETVTV 96
>XP_005261300
          Length = 956

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VEETITV 8
          +EET+TV
Sbjct: 90 LEETVTV 96
>XP_006724307
          Length = 986

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VEETITV 8
          +EET+TV
Sbjct: 90 LEETVTV 96
>XP_005261299
          Length = 998

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VEETITV 8
          +EET+TV
Sbjct: 90 LEETVTV 96
>XP_006724306
          Length = 1004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VEETITV 8
          +EET+TV
Sbjct: 90 LEETVTV 96
>XP_006720757
          Length = 1008

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   VEETIT 7
           VEETIT
Sbjct: 562 VEETIT 567
>XP_006720756
          Length = 1229

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   VEETIT 7
           VEETIT
Sbjct: 783 VEETIT 788
>XP_006720304
          Length = 2328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VEETITV 8
           +E+TITV
Sbjct: 318 IEQTITV 324
>XP_005268080
          Length = 2328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VEETITV 8
           +E+TITV
Sbjct: 318 IEQTITV 324
>XP_005267567
          Length = 721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  EETITVR 9
          E+T+T+R
Sbjct: 66 EQTVTIR 72
>XP_005268747
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVEETITV 8
           K+EE++TV
Sbjct: 461 KLEESLTV 468
>XP_005268746
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVEETITV 8
           K+EE++TV
Sbjct: 461 KLEESLTV 468
>XP_005268745
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVEETITV 8
           K+EE++TV
Sbjct: 611 KLEESLTV 618
>XP_006718184
          Length = 367

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVEETITV 8
           K+E+TIT+
Sbjct: 137 KLEDTITL 144
>XP_005252787
          Length = 498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVEETITV 8
           K+E+TIT+
Sbjct: 268 KLEDTITL 275
>XP_005270205
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  KVEETIT 7
          K+EET+T
Sbjct: 60 KLEETLT 66
>XP_005249975
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KVEETITVR 9
           K EE+ITV+
Sbjct: 244 KQEESITVQ 252
>NP_054764
          Length = 713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  EETITVR 9
          E+T+T+R
Sbjct: 66 EQTVTIR 72
>NP_002207
          Length = 946

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  KVEETITVR 9
          KV+ TIT R
Sbjct: 76 KVQSTITSR 84
>NP_076950
          Length = 737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KVEETIT 7
           K+EET+T
Sbjct: 125 KLEETLT 131
>NP_958853
          Length = 735

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KVEETITV 8
           K+EE++TV
Sbjct: 573 KLEESLTV 580
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.125    0.290 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 462,329
Number of extensions: 814
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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