Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     665
NP_671714                                                              19     665
XP_006715890                                                           19     665
XP_005250160                                                           19     665
XP_005250159                                                           19     665
NP_001073881                                                           17    4312
NP_060860                                                              17    4312
XP_006724930                                                           17    4312
XP_006724929                                                           17    4312
XP_006724928                                                           17    4312
XP_006724509                                                           17    4312
XP_006724508                                                           17    4312
XP_006724507                                                           17    4312
XP_006713622                                                           17    4312
XP_005247320                                                           17    4312
XP_005247319                                                           17    4312
XP_005247318                                                           17    4312
XP_005247315                                                           17    4312
XP_005247314                                                           17    4312
XP_005247313                                                           17    4312
XP_005247312                                                           17    4312
NP_899236                                                              16    5631
NP_056363                                                              16    5631
NP_001138241                                                           16    5631
NP_001138242                                                           16    5631
XP_005273659                                                           16    5631
XP_006716448                                                           16    5631
XP_006716447                                                           16    5631
XP_006716446                                                           16    5631
XP_006716445                                                           16    5631
XP_006716444                                                           16    5631
XP_006715232                                                           16    5631
XP_005249382                                                           16    5631
XP_005249381                                                           16    5631
XP_005249380                                                           16    5631
XP_005249379                                                           16    5631
XP_005249377                                                           16    5631
XP_005249376                                                           16    5631
XP_005249375                                                           16    5631
XP_005249374                                                           16    5631
XP_005249373                                                           16    5631
XP_005249372                                                           16    5631
XP_005249371                                                           16    5631
XP_005249370                                                           16    5631
XP_005249369                                                           16    5631
XP_005249368                                                           16    5631
XP_005249367                                                           16    5631
NP_073586                                                              16    5631
NP_775082                                                              15    9605
NP_003377                                                              15    9605
NP_056127                                                              15    9605
NP_002171                                                              15    9605
NP_001161707                                                           15    9605
XP_005274034                                                           15    9605
XP_005274033                                                           15    9605
XP_006714407                                                           15    9605
XP_006714406                                                           15    9605
XP_006714405                                                           15    9605
XP_005263349                                                           15    9605
XP_005263348                                                           15    9605
XP_005263347                                                           15    9605
XP_005263346                                                           15    9605
XP_005263345                                                           15    9605
XP_005263344                                                           15    9605
XP_005263343                                                           15    9605
XP_005263342                                                           15    9605
XP_005263341                                                           15    9605
XP_005263340                                                           15    9605
XP_005263339                                                           15    9605
>NP_005742
          Length = 3907

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KTTAVVEET 9
            KTTA VEET
Sbjct: 1740 KTTAAVEET 1748
>NP_671714
          Length = 3899

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KTTAVVEET 9
            KTTA VEET
Sbjct: 1740 KTTAAVEET 1748
>XP_006715890
          Length = 3860

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KTTAVVEET 9
            KTTA VEET
Sbjct: 1693 KTTAAVEET 1701
>XP_005250160
          Length = 3939

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KTTAVVEET 9
            KTTA VEET
Sbjct: 1772 KTTAAVEET 1780
>XP_005250159
          Length = 3952

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    KTTAVVEET 9
            KTTA VEET
Sbjct: 1772 KTTAAVEET 1780
>NP_001073881
          Length = 1195

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KTTAVVEET 9
           KTT + EET
Sbjct: 804 KTTNIAEET 812
>NP_060860
          Length = 323

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TTAVVEET 9
           TTA+VE+T
Sbjct: 126 TTALVEDT 133
>XP_006724930
          Length = 323

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TTAVVEET 9
           TTA+VE+T
Sbjct: 126 TTALVEDT 133
>XP_006724929
          Length = 323

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TTAVVEET 9
           TTA+VE+T
Sbjct: 126 TTALVEDT 133
>XP_006724928
          Length = 323

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TTAVVEET 9
           TTA+VE+T
Sbjct: 126 TTALVEDT 133
>XP_006724509
          Length = 323

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TTAVVEET 9
           TTA+VE+T
Sbjct: 126 TTALVEDT 133
>XP_006724508
          Length = 323

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TTAVVEET 9
           TTA+VE+T
Sbjct: 126 TTALVEDT 133
>XP_006724507
          Length = 323

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   TTAVVEET 9
           TTA+VE+T
Sbjct: 126 TTALVEDT 133
>XP_006713622
          Length = 1195

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KTTAVVEET 9
           KTT + EET
Sbjct: 804 KTTNIAEET 812
>XP_005247320
          Length = 1195

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KTTAVVEET 9
           KTT + EET
Sbjct: 804 KTTNIAEET 812
>XP_005247319
          Length = 1195

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KTTAVVEET 9
           KTT + EET
Sbjct: 804 KTTNIAEET 812
>XP_005247318
          Length = 1195

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KTTAVVEET 9
           KTT + EET
Sbjct: 804 KTTNIAEET 812
>XP_005247315
          Length = 1195

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KTTAVVEET 9
           KTT + EET
Sbjct: 804 KTTNIAEET 812
>XP_005247314
          Length = 1195

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KTTAVVEET 9
           KTT + EET
Sbjct: 804 KTTNIAEET 812
>XP_005247313
          Length = 1196

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KTTAVVEET 9
           KTT + EET
Sbjct: 805 KTTNIAEET 813
>XP_005247312
          Length = 1231

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KTTAVVEET 9
           KTT + EET
Sbjct: 840 KTTNIAEET 848
>NP_899236
          Length = 5497

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TTAVVEET 9
            TTA+ EET
Sbjct: 1670 TTAIKEET 1677
>NP_056363
          Length = 5171

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TTAVVEET 9
            TTA+ EET
Sbjct: 1344 TTAIKEET 1351
>NP_001138241
          Length = 5675

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TTAVVEET 9
            TTA+ EET
Sbjct: 1848 TTAIKEET 1855
>NP_001138242
          Length = 5537

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TTAVVEET 9
            TTA+ EET
Sbjct: 1710 TTAIKEET 1717
>XP_005273659
          Length = 629

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KTTAVVEET 9
           KT+A +EET
Sbjct: 549 KTSAFLEET 557
>XP_006716448
          Length = 650

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KTTAVVEET 9
           KT+A +EET
Sbjct: 446 KTSAFLEET 454
>XP_006716447
          Length = 650

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KTTAVVEET 9
           KT+A +EET
Sbjct: 446 KTSAFLEET 454
>XP_006716446
          Length = 695

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KTTAVVEET 9
           KT+A +EET
Sbjct: 491 KTSAFLEET 499
>XP_006716445
          Length = 695

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KTTAVVEET 9
           KT+A +EET
Sbjct: 491 KTSAFLEET 499
>XP_006716444
          Length = 753

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KTTAVVEET 9
           KT+A +EET
Sbjct: 549 KTSAFLEET 557
>XP_006715232
          Length = 7498

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TTAVVEET 9
            TTA+ EET
Sbjct: 3756 TTAIKEET 3763
>XP_005249382
          Length = 5732

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TTAVVEET 9
            TTA+ EET
Sbjct: 1881 TTAIKEET 1888
>XP_005249381
          Length = 7281

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TTAVVEET 9
            TTA+ EET
Sbjct: 3430 TTAIKEET 3437
>XP_005249380
          Length = 7607

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TTAVVEET 9
            TTA+ EET
Sbjct: 3756 TTAIKEET 3763
>XP_005249379
          Length = 7633

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TTAVVEET 9
            TTA+ EET
Sbjct: 3782 TTAIKEET 3789
>XP_005249377
          Length = 7640

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TTAVVEET 9
            TTA+ EET
Sbjct: 3789 TTAIKEET 3796
>XP_005249376
          Length = 7647

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TTAVVEET 9
            TTA+ EET
Sbjct: 3796 TTAIKEET 3803
>XP_005249375
          Length = 7680

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TTAVVEET 9
            TTA+ EET
Sbjct: 3829 TTAIKEET 3836
>XP_005249374
          Length = 7709

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TTAVVEET 9
            TTA+ EET
Sbjct: 3967 TTAIKEET 3974
>XP_005249373
          Length = 7723

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TTAVVEET 9
            TTA+ EET
Sbjct: 3872 TTAIKEET 3879
>XP_005249372
          Length = 7785

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TTAVVEET 9
            TTA+ EET
Sbjct: 3934 TTAIKEET 3941
>XP_005249371
          Length = 7788

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TTAVVEET 9
            TTA+ EET
Sbjct: 3967 TTAIKEET 3974
>XP_005249370
          Length = 7794

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TTAVVEET 9
            TTA+ EET
Sbjct: 3967 TTAIKEET 3974
>XP_005249369
          Length = 7797

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TTAVVEET 9
            TTA+ EET
Sbjct: 3946 TTAIKEET 3953
>XP_005249368
          Length = 7812

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TTAVVEET 9
            TTA+ EET
Sbjct: 3967 TTAIKEET 3974
>XP_005249367
          Length = 7818

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    TTAVVEET 9
            TTA+ EET
Sbjct: 3967 TTAIKEET 3974
>NP_073586
          Length = 743

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KTTAVVEET 9
           KT+A +EET
Sbjct: 549 KTSAFLEET 557
>NP_775082
          Length = 2721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KTTAVVEET 9
           +TT  VEET
Sbjct: 828 ETTTSVEET 836
>NP_003377
          Length = 2812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KTTAVVEET 9
           +TT  VEET
Sbjct: 828 ETTTSVEET 836
>NP_056127
          Length = 5005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KTTAVVE 7
            +TTA+VE
Sbjct: 1614 RTTAIVE 1620
>NP_002171
          Length = 993

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   KTTAVVE 7
           KTT VVE
Sbjct: 220 KTTTVVE 226
>NP_001161707
          Length = 2139

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    KTTAVVEET 9
            KTT  +E+T
Sbjct: 2118 KTTIFIEDT 2126
>XP_005274034
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   KTTAVVE 7
           KTT VVE
Sbjct: 220 KTTTVVE 226
>XP_005274033
          Length = 540

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   KTTAVVE 7
           KTT VVE
Sbjct: 220 KTTTVVE 226
>XP_006714407
          Length = 5004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KTTAVVE 7
            +TTA+VE
Sbjct: 1613 RTTAIVE 1619
>XP_006714406
          Length = 3680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KTTAVVE 7
            +TTA+VE
Sbjct: 1614 RTTAIVE 1620
>XP_006714405
          Length = 4103

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KTTAVVE 7
           +TTA+VE
Sbjct: 691 RTTAIVE 697
>XP_005263349
          Length = 4410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KTTAVVE 7
            +TTA+VE
Sbjct: 998  RTTAIVE 1004
>XP_005263348
          Length = 4443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KTTAVVE 7
            +TTA+VE
Sbjct: 1031 RTTAIVE 1037
>XP_005263347
          Length = 4640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KTTAVVE 7
            +TTA+VE
Sbjct: 1614 RTTAIVE 1620
>XP_005263346
          Length = 4983

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KTTAVVE 7
            +TTA+VE
Sbjct: 1571 RTTAIVE 1577
>XP_005263345
          Length = 4991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KTTAVVE 7
            +TTA+VE
Sbjct: 1614 RTTAIVE 1620
>XP_005263344
          Length = 5005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KTTAVVE 7
            +TTA+VE
Sbjct: 1614 RTTAIVE 1620
>XP_005263343
          Length = 5009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KTTAVVE 7
            +TTA+VE
Sbjct: 1614 RTTAIVE 1620
>XP_005263342
          Length = 5025

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KTTAVVE 7
            +TTA+VE
Sbjct: 1613 RTTAIVE 1619
>XP_005263341
          Length = 5026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KTTAVVE 7
            +TTA+VE
Sbjct: 1614 RTTAIVE 1620
>XP_005263340
          Length = 5026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KTTAVVE 7
            +TTA+VE
Sbjct: 1614 RTTAIVE 1620
>XP_005263339
          Length = 5026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    KTTAVVE 7
            +TTA+VE
Sbjct: 1614 RTTAIVE 1620
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.288    0.102    0.228 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 371,700
Number of extensions: 448
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

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