Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_056045                                                              16    5631
NP_001269166                                                           16    5631
NP_001269167                                                           16    5631
NP_075049                                                              16    5631
NP_612808                                                              16    5631
XP_005262699                                                           16    5631
XP_005262697                                                           16    5631
XP_006714054                                                           16    5631
XP_005262695                                                           16    5631
NP_005888                                                              16    7355
NP_006705                                                              16    7355
NP_001138821                                                           16    7355
XP_005266856                                                           16    7355
XP_005266855                                                           16    7355
XP_006710686                                                           16    7355
XP_005270897                                                           16    7355
XP_005270896                                                           16    7355
XP_006710685                                                           16    7355
NP_001139669                                                           16    7355
NP_006682                                                              15    9605
NP_036582                                                              15    9605
XP_005250318                                                           15    9605
>NP_056045
          Length = 1704

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSGLGVMV 8
           KSGLG+ +
Sbjct: 622 KSGLGITI 629
>NP_001269166
          Length = 893

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  SGLGVMV 8
          SGLG+MV
Sbjct: 41 SGLGLMV 47
>NP_001269167
          Length = 822

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  SGLGVMV 8
          SGLG+MV
Sbjct: 41 SGLGLMV 47
>NP_075049
          Length = 823

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  SGLGVMV 8
          SGLG+MV
Sbjct: 42 SGLGLMV 48
>NP_612808
          Length = 894

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  SGLGVMV 8
          SGLG+MV
Sbjct: 42 SGLGLMV 48
>XP_005262699
          Length = 1005

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSGLGVMV 8
           KSGLG+ +
Sbjct: 622 KSGLGITI 629
>XP_005262697
          Length = 1681

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSGLGVMV 8
           KSGLG+ +
Sbjct: 622 KSGLGITI 629
>XP_006714054
          Length = 1693

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSGLGVMV 8
           KSGLG+ +
Sbjct: 611 KSGLGITI 618
>XP_005262695
          Length = 1704

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSGLGVMV 8
           KSGLG+ +
Sbjct: 622 KSGLGITI 629
>NP_005888
          Length = 584

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KSGLGVMV 8
           +SGLGV V
Sbjct: 333 RSGLGVTV 340
>NP_006705
          Length = 453

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSGLGVMVA 9
          +SGLG+ VA
Sbjct: 18 RSGLGLPVA 26
>NP_001138821
          Length = 582

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KSGLGVMV 8
           +SGLGV V
Sbjct: 333 RSGLGVTV 340
>XP_005266856
          Length = 338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSGLGVMVA 9
          +SGLG+ VA
Sbjct: 18 RSGLGLPVA 26
>XP_005266855
          Length = 364

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSGLGVMVA 9
          +SGLG+ VA
Sbjct: 18 RSGLGLPVA 26
>XP_006710686
          Length = 440

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KSGLGVMV 8
           +SGLGV V
Sbjct: 333 RSGLGVTV 340
>XP_005270897
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KSGLGVMV 8
           +SGLGV V
Sbjct: 333 RSGLGVTV 340
>XP_005270896
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KSGLGVMV 8
           +SGLGV V
Sbjct: 333 RSGLGVTV 340
>XP_006710685
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KSGLGVMV 8
           +SGLGV V
Sbjct: 333 RSGLGVTV 340
>NP_001139669
          Length = 7081

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KSGLGVMVA 9
            KSG GVM++
Sbjct: 5194 KSGPGVMLS 5202
>NP_006682
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   KSGLGVMV 8
           K+G+GV++
Sbjct: 108 KNGVGVLI 115
>NP_036582
          Length = 626

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KSGLGVMV 8
           K+GLGV V
Sbjct: 583 KAGLGVNV 590
>XP_005250318
          Length = 627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KSGLGVMV 8
           K+GLGV V
Sbjct: 584 KAGLGVNV 591
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.317    0.134    0.349 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 472,718
Number of extensions: 631
Number of successful extensions: 22
Number of sequences better than 10000.0: 22
Number of HSP's gapped: 22
Number of HSP's successfully gapped: 22
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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