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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              18    1135
XP_006714104                                                           18    1135
XP_005265800                                                           18    1135
XP_006714103                                                           18    1135
XP_006714102                                                           18    1135
XP_006716203                                                           17    2528
NP_872625                                                              17    2528
NP_001161046                                                           17    4312
NP_008884                                                              17    4312
NP_057186                                                              17    4312
NP_001020111                                                           17    4312
XP_006711842                                                           17    4312
NP_000115                                                              16    5631
NP_001170904                                                           16    7355
NP_001077073                                                           16    7355
NP_001077075                                                           16    7355
NP_001077076                                                           16    7355
NP_001077072                                                           16    7355
NP_001077071                                                           16    7355
NP_000255                                                              16    7355
NP_001077074                                                           16    7355
NP_001170899                                                           16    7355
NP_001170902                                                           16    7355
NP_671737                                                              16    7355
NP_067638                                                              16    7355
NP_940959                                                              16    7355
XP_005253976                                                           16    7355
XP_005253975                                                           16    7355
XP_005252159                                                           16    7355
NP_060952                                                              15    9605
NP_001234925                                                           15    9605
XP_006716630                                                           15    9605
XP_006716629                                                           15    9605
XP_006716628                                                           15    9605
XP_006716627                                                           15    9605
XP_006716626                                                           15    9605
XP_005250982                                                           15    9605

>NP_006197
          Length = 1089

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KSGEMIVVT 9
           KSGE IVVT
Sbjct: 226 KSGETIVVT 234



>XP_006714104
          Length = 832

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KSGEMIVVT 9
           KSGE IVVT
Sbjct: 251 KSGETIVVT 259



>XP_005265800
          Length = 1089

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KSGEMIVVT 9
           KSGE IVVT
Sbjct: 226 KSGETIVVT 234



>XP_006714103
          Length = 1111

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KSGEMIVVT 9
           KSGE IVVT
Sbjct: 248 KSGETIVVT 256



>XP_006714102
          Length = 1114

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KSGEMIVVT 9
           KSGE IVVT
Sbjct: 251 KSGETIVVT 259



>XP_006716203
          Length = 276

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KSGEMIVVT 9
           +SG MIV+T
Sbjct: 194 RSGSMIVIT 202



>NP_872625
          Length = 276

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KSGEMIVVT 9
           +SG MIV+T
Sbjct: 194 RSGSMIVIT 202



>NP_001161046
          Length = 166

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KSGEMIVVT 9
          +SG MIV+T
Sbjct: 83 RSGGMIVIT 91



>NP_008884
          Length = 287

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KSGEMIVVT 9
           +SG MIV+T
Sbjct: 204 RSGGMIVIT 212



>NP_057186
          Length = 477

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KSGEMIVVT 9
           KSG+M++ T
Sbjct: 462 KSGQMVIST 470



>NP_001020111
          Length = 477

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KSGEMIVVT 9
           KSG+M++ T
Sbjct: 462 KSGQMVIST 470



>XP_006711842
          Length = 477

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KSGEMIVVT 9
           KSG+M++ T
Sbjct: 462 KSGQMVIST 470



>NP_000115
          Length = 1493

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KSGEMIVV 8
           +SG+MIVV
Sbjct: 837 RSGKMIVV 844



>NP_001170904
          Length = 764

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSGEMIVV 8
           +SGEM+ V
Sbjct: 650 RSGEMVTV 657



>NP_001077073
          Length = 1296

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  KSGEMIVVT 9
          KSGE+I  T
Sbjct: 54 KSGELITET 62



>NP_001077075
          Length = 1296

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  KSGEMIVVT 9
          KSGE+I  T
Sbjct: 54 KSGELITET 62



>NP_001077076
          Length = 1296

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  KSGEMIVVT 9
          KSGE+I  T
Sbjct: 54 KSGELITET 62



>NP_001077072
          Length = 1446

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSGEMIVVT 9
           KSGE+I  T
Sbjct: 204 KSGELITET 212



>NP_001077071
          Length = 1381

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSGEMIVVT 9
           KSGE+I  T
Sbjct: 139 KSGELITET 147



>NP_000255
          Length = 1447

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KSGEMIVVT 9
           KSGE+I  T
Sbjct: 205 KSGELITET 213



>NP_001077074
          Length = 1296

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  KSGEMIVVT 9
          KSGE+I  T
Sbjct: 54 KSGELITET 62



>NP_001170899
          Length = 824

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSGEMIVV 8
           +SGEM+ V
Sbjct: 710 RSGEMVTV 717



>NP_001170902
          Length = 837

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSGEMIVV 8
           +SGEM+ V
Sbjct: 723 RSGEMVTV 730



>NP_671737
          Length = 811

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSGEMIVV 8
           +SGEM+ V
Sbjct: 697 RSGEMVTV 704



>NP_067638
          Length = 871

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSGEMIVV 8
           +SGEM+ V
Sbjct: 757 RSGEMVTV 764



>NP_940959
          Length = 357

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KSGEMIVV 8
           +SGEM+V+
Sbjct: 215 RSGEMLVL 222



>XP_005253976
          Length = 837

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSGEMIVV 8
           +SGEM+ V
Sbjct: 723 RSGEMVTV 730



>XP_005253975
          Length = 871

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KSGEMIVV 8
           +SGEM+ V
Sbjct: 757 RSGEMVTV 764



>XP_005252159
          Length = 1296

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  KSGEMIVVT 9
          KSGE+I  T
Sbjct: 54 KSGELITET 62



>NP_060952
          Length = 1129

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    GEMIVVT 9
            GE+I+VT
Sbjct: 1091 GEVIIVT 1097



>NP_001234925
          Length = 1122

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    GEMIVVT 9
            GE+I+VT
Sbjct: 1084 GEVIIVT 1090



>XP_006716630
          Length = 1073

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    GEMIVVT 9
            GE+I+VT
Sbjct: 1035 GEVIIVT 1041



>XP_006716629
          Length = 1075

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    GEMIVVT 9
            GE+I+VT
Sbjct: 1037 GEVIIVT 1043



>XP_006716628
          Length = 1076

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    GEMIVVT 9
            GE+I+VT
Sbjct: 1038 GEVIIVT 1044



>XP_006716627
          Length = 1125

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    GEMIVVT 9
            GE+I+VT
Sbjct: 1087 GEVIIVT 1093



>XP_006716626
          Length = 1132

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    GEMIVVT 9
            GE+I+VT
Sbjct: 1094 GEVIIVT 1100



>XP_005250982
          Length = 1132

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    GEMIVVT 9
            GE+I+VT
Sbjct: 1094 GEVIIVT 1100



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.311    0.127    0.307 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 454,452
Number of extensions: 518
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)