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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001257436                                                           18    1135
NP_001257437                                                           18    1135
NP_006281                                                              18    1135
XP_006715618                                                           18    1135
XP_005267176                                                           18    1135
NP_001160158                                                           16    7355
XP_005269036                                                           16    7355
XP_005269035                                                           16    7355
XP_005269034                                                           16    7355
XP_005269033                                                           16    7355
XP_005269032                                                           16    7355
XP_005269031                                                           16    7355
NP_005545                                                              15    9605
NP_005546                                                              15    9605
NP_775109                                                              15    9605
NP_000414                                                              15    9605
NP_258259                                                              15    9605
NP_056932                                                              15    9605
NP_004684                                                              15    9605
NP_476429                                                              15    9605
NP_002263                                                              15    9605
NP_001193856                                                           15    9605
XP_006719456                                                           15    9605
XP_005268916                                                           15    9605
XP_006719455                                                           15    9605
XP_006715067                                                           15    9605

>NP_001257436
          Length = 790

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KRTAAEASS 9
           KRT AEASS
Sbjct: 541 KRTTAEASS 549



>NP_001257437
          Length = 790

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KRTAAEASS 9
           KRT AEASS
Sbjct: 541 KRTTAEASS 549



>NP_006281
          Length = 790

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KRTAAEASS 9
           KRT AEASS
Sbjct: 541 KRTTAEASS 549



>XP_006715618
          Length = 577

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KRTAAEASS 9
           KRT AEASS
Sbjct: 328 KRTTAEASS 336



>XP_005267176
          Length = 790

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KRTAAEASS 9
           KRT AEASS
Sbjct: 541 KRTTAEASS 549



>NP_001160158
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KRTAAEASS 9
          +RTA EAS+
Sbjct: 25 QRTAGEAST 33



>XP_005269036
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KRTAAEASS 9
          +RTA EAS+
Sbjct: 25 QRTAGEAST 33



>XP_005269035
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KRTAAEASS 9
          +RTA EAS+
Sbjct: 25 QRTAGEAST 33



>XP_005269034
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KRTAAEASS 9
          +RTA EAS+
Sbjct: 25 QRTAGEAST 33



>XP_005269033
          Length = 883

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KRTAAEASS 9
          +RTA EAS+
Sbjct: 25 QRTAGEAST 33



>XP_005269032
          Length = 883

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KRTAAEASS 9
          +RTA EAS+
Sbjct: 25 QRTAGEAST 33



>XP_005269031
          Length = 883

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KRTAAEASS 9
          +RTA EAS+
Sbjct: 25 QRTAGEAST 33



>NP_005545
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KRTAAE 6
           KRTAAE
Sbjct: 259 KRTAAE 264



>NP_005546
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KRTAAE 6
           KRTAAE
Sbjct: 259 KRTAAE 264



>NP_775109
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KRTAAE 6
           KRTAAE
Sbjct: 259 KRTAAE 264



>NP_000414
          Length = 639

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KRTAAE 6
           KRTAAE
Sbjct: 274 KRTAAE 279



>NP_258259
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KRTAAE 6
           KRTAAE
Sbjct: 226 KRTAAE 231



>NP_056932
          Length = 638

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KRTAAE 6
           KRTAAE
Sbjct: 279 KRTAAE 284



>NP_004684
          Length = 551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KRTAAE 6
           KRTAAE
Sbjct: 245 KRTAAE 250



>NP_476429
          Length = 628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KRTAAE 6
           KRTAAE
Sbjct: 296 KRTAAE 301



>NP_002263
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KRTAAE 6
           KRTAAE
Sbjct: 233 KRTAAE 238



>NP_001193856
          Length = 4707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KRTAAEAS 8
            K+TAAE S
Sbjct: 3871 KQTAAEVS 3878



>XP_006719456
          Length = 580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KRTAAE 6
           KRTAAE
Sbjct: 248 KRTAAE 253



>XP_005268916
          Length = 606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KRTAAE 6
           KRTAAE
Sbjct: 274 KRTAAE 279



>XP_006719455
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KRTAAE 6
           KRTAAE
Sbjct: 284 KRTAAE 289



>XP_006715067
          Length = 4707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    KRTAAEAS 8
            K+TAAE S
Sbjct: 3871 KQTAAEVS 3878



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.280   0.0874    0.184 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 189,252
Number of extensions: 151
Number of successful extensions: 26
Number of sequences better than 10000.0: 26
Number of HSP's gapped: 26
Number of HSP's successfully gapped: 26
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)