Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000542                                                              19     665
NP_937799                                                              19     665
NP_001006635                                                           17    4312
NP_060524                                                              17    4312
XP_006721123                                                           17    4312
XP_005255471                                                           17    4312
XP_006721121                                                           17    4312
XP_005255470                                                           17    4312
XP_006721120                                                           17    4312
NP_004256                                                              16    5631
NP_001268430                                                           16    5631
NP_001268431                                                           16    5631
NP_060525                                                              16    5631
NP_060493                                                              16    5631
XP_006713751                                                           16    5631
XP_005247655                                                           16    5631
XP_005247654                                                           16    5631
NP_061178                                                              16    5631
NP_660312                                                              16    7355
NP_001269963                                                           16    7355
XP_006716569                                                           16    7355
XP_005250844                                                           16    7355
XP_005250843                                                           16    7355
XP_005250841                                                           16    7355
XP_005250840                                                           16    7355
NP_001171921                                                           15    9605
NP_115698                                                              15    9605
NP_922921                                                              15    9605
NP_055476                                                              15    9605
NP_001138830                                                           15    9605
NP_001138829                                                           15    9605
NP_056292                                                              15    9605
NP_002800                                                              15    9605
NP_056075                                                              15    9605
NP_055553                                                              15    9605
NP_068373                                                              15    9605
XP_006722767                                                           15    9605
XP_005259889                                                           15    9605
XP_005257925                                                           15    9605
XP_005257924                                                           15    9605
XP_005257923                                                           15    9605
XP_005257922                                                           15    9605
XP_005257921                                                           15    9605
XP_006722263                                                           15    9605
XP_005257920                                                           15    9605
XP_006722201                                                           15    9605
XP_006720530                                                           15    9605
XP_006720529                                                           15    9605
XP_006720528                                                           15    9605
>NP_000542
          Length = 213

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KRLDIVRSL 9
           +RLDIVRSL
Sbjct: 176 RRLDIVRSL 184
>NP_937799
          Length = 172

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KRLDIVRSL 9
           +RLDIVRSL
Sbjct: 135 RRLDIVRSL 143
>NP_001006635
          Length = 881

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KRLDIVRSL 9
          +RLD VRS+
Sbjct: 34 RRLDTVRSI 42
>NP_060524
          Length = 803

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KRLDIVRSL 9
          +RLD VRS+
Sbjct: 34 RRLDTVRSI 42
>XP_006721123
          Length = 775

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KRLDIVRSL 9
          +RLD VRS+
Sbjct: 34 RRLDTVRSI 42
>XP_005255471
          Length = 840

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KRLDIVRSL 9
          +RLD VRS+
Sbjct: 34 RRLDTVRSI 42
>XP_006721121
          Length = 853

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KRLDIVRSL 9
          +RLD VRS+
Sbjct: 34 RRLDTVRSI 42
>XP_005255470
          Length = 853

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KRLDIVRSL 9
          +RLD VRS+
Sbjct: 34 RRLDTVRSI 42
>XP_006721120
          Length = 880

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KRLDIVRSL 9
          +RLD VRS+
Sbjct: 33 RRLDTVRSI 41
>NP_004256
          Length = 444

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDIVRSL 9
           LDI+RSL
Sbjct: 424 LDIIRSL 430
>NP_001268430
          Length = 422

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDIVRSL 9
           LDI+RSL
Sbjct: 402 LDIIRSL 408
>NP_001268431
          Length = 413

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDIVRSL 9
           LDI+RSL
Sbjct: 393 LDIIRSL 399
>NP_060525
          Length = 347

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  RLDIVRSL 9
          R DI+RSL
Sbjct: 54 RADIIRSL 61
>NP_060493
          Length = 1422

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KRLDIVRSL 9
           KR+DI+ +L
Sbjct: 299 KRIDIIHNL 307
>XP_006713751
          Length = 1423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KRLDIVRSL 9
           KR+DI+ +L
Sbjct: 299 KRIDIIHNL 307
>XP_005247655
          Length = 1423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KRLDIVRSL 9
           KR+DI+ +L
Sbjct: 299 KRIDIIHNL 307
>XP_005247654
          Length = 1423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KRLDIVRSL 9
           KR+DI+ +L
Sbjct: 299 KRIDIIHNL 307
>NP_061178
          Length = 669

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDIVRSL 9
           LD+VRSL
Sbjct: 96  LDVVRSL 102
>NP_660312
          Length = 289

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RLDIVRS 8
           RLDIVR+
Sbjct: 233 RLDIVRA 239
>NP_001269963
          Length = 251

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RLDIVRS 8
           RLDIVR+
Sbjct: 195 RLDIVRA 201
>XP_006716569
          Length = 289

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RLDIVRS 8
           RLDIVR+
Sbjct: 233 RLDIVRA 239
>XP_005250844
          Length = 219

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RLDIVRS 8
           RLDIVR+
Sbjct: 163 RLDIVRA 169
>XP_005250843
          Length = 227

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RLDIVRS 8
           RLDIVR+
Sbjct: 171 RLDIVRA 177
>XP_005250841
          Length = 259

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RLDIVRS 8
           RLDIVR+
Sbjct: 203 RLDIVRA 209
>XP_005250840
          Length = 297

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RLDIVRS 8
           RLDIVR+
Sbjct: 241 RLDIVRA 247
>NP_001171921
          Length = 286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDIVRSL 9
           +DIVRSL
Sbjct: 146 VDIVRSL 152
>NP_115698
          Length = 432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDIVRSL 9
           +DIVRSL
Sbjct: 146 VDIVRSL 152
>NP_922921
          Length = 210

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDIVRSL 9
           +DIVRSL
Sbjct: 146 VDIVRSL 152
>NP_055476
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RLDIVRSL 9
           RLD+ RSL
Sbjct: 222 RLDLQRSL 229
>NP_001138830
          Length = 1273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDIVRSL 9
           LD+VRSL
Sbjct: 963 LDMVRSL 969
>NP_001138829
          Length = 1273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDIVRSL 9
           LD+VRSL
Sbjct: 963 LDMVRSL 969
>NP_056292
          Length = 1273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDIVRSL 9
           LD+VRSL
Sbjct: 963 LDMVRSL 969
>NP_002800
          Length = 534

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RLDIVRS 8
           +LD+VRS
Sbjct: 223 KLDVVRS 229
>NP_056075
          Length = 1162

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDIVRSL 9
           LD+VRSL
Sbjct: 852 LDMVRSL 858
>NP_055553
          Length = 1356

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   RLDIVR 7
           RLDIVR
Sbjct: 834 RLDIVR 839
>NP_068373
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDIVRSL 9
           +DIVRSL
Sbjct: 425 VDIVRSL 431
>XP_006722767
          Length = 645

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDIVRSL 9
           LD+VRSL
Sbjct: 335 LDMVRSL 341
>XP_005259889
          Length = 1130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDIVRSL 9
           LD+VRSL
Sbjct: 820 LDMVRSL 826
>XP_005257925
          Length = 850

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   RLDIVR 7
           RLDIVR
Sbjct: 298 RLDIVR 303
>XP_005257924
          Length = 1122

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   RLDIVR 7
           RLDIVR
Sbjct: 570 RLDIVR 575
>XP_005257923
          Length = 1131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   RLDIVR 7
           RLDIVR
Sbjct: 579 RLDIVR 584
>XP_005257922
          Length = 1366

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   RLDIVR 7
           RLDIVR
Sbjct: 844 RLDIVR 849
>XP_005257921
          Length = 1370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   RLDIVR 7
           RLDIVR
Sbjct: 848 RLDIVR 853
>XP_006722263
          Length = 1390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   RLDIVR 7
           RLDIVR
Sbjct: 838 RLDIVR 843
>XP_005257920
          Length = 1390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   RLDIVR 7
           RLDIVR
Sbjct: 838 RLDIVR 843
>XP_006722201
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  LDIVRSL 9
          +DIVRSL
Sbjct: 39 VDIVRSL 45
>XP_006720530
          Length = 1273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDIVRSL 9
           LD+VRSL
Sbjct: 963 LDMVRSL 969
>XP_006720529
          Length = 1273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDIVRSL 9
           LD+VRSL
Sbjct: 963 LDMVRSL 969
>XP_006720528
          Length = 1273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDIVRSL 9
           LD+VRSL
Sbjct: 963 LDMVRSL 969
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.334    0.150    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 375,814
Number of extensions: 444
Number of successful extensions: 49
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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