Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              21     229
XP_006716142                                                           21     229
XP_005250088                                                           21     229
XP_006716141                                                           21     229
XP_005250085                                                           21     229
XP_006716140                                                           21     229
XP_005250084                                                           21     229
XP_005250083                                                           21     229
XP_005250082                                                           21     229
NP_001078823                                                           18    1135
NP_078933                                                              18    1135
XP_006724755                                                           18    1135
XP_006724754                                                           18    1135
XP_005262247                                                           18    1135
NP_001263200                                                           17    2528
NP_004587                                                              17    4312
NP_001182474                                                           17    4312
XP_005252339                                                           17    4312
NP_937863                                                              17    4312
NP_003083                                                              17    4312
NP_116198                                                              17    4312
NP_001438                                                              16    5631
NP_001107580                                                           16    5631
NP_573439                                                              16    5631
NP_573438                                                              16    5631
NP_001181930                                                           16    5631
NP_005695                                                              16    5631
XP_006723819                                                           16    5631
XP_006714824                                                           16    5631
XP_006710334                                                           16    5631
XP_006710333                                                           16    5631
XP_006710332                                                           16    5631
NP_006781                                                              16    7355
NP_001129412                                                           16    7355
NP_001004334                                                           16    7355
NP_006030                                                              16    7355
NP_001139373                                                           16    7355
NP_705618                                                              16    7355
NP_004289                                                              16    7355
NP_001265241                                                           16    7355
XP_005262550                                                           16    7355
XP_005272186                                                           16    7355
NP_997244                                                              15    9605
NP_001186226                                                           15    9605
NP_001129477                                                           15    9605
NP_057374                                                              15    9605
NP_001129478                                                           15    9605
NP_006681                                                              15    9605
NP_997213                                                              15    9605
NP_000810                                                              15    9605
NP_112598                                                              15    9605
NP_001186227                                                           15    9605
XP_006724053                                                           15    9605
XP_006724052                                                           15    9605
XP_005260998                                                           15    9605
XP_006724051                                                           15    9605
XP_005256913                                                           15    9605
XP_005265993                                                           15    9605
XP_006714937                                                           15    9605
XP_005265992                                                           15    9605
XP_005265991                                                           15    9605
XP_005265990                                                           15    9605
XP_005265989                                                           15    9605
XP_006714936                                                           15    9605
XP_006714935                                                           15    9605
XP_005265988                                                           15    9605
XP_006714934                                                           15    9605
XP_005265987                                                           15    9605
NP_780294                                                              15    9605
NP_981956                                                              15    9605
>NP_733751
          Length = 4911

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KQVRITPGF 9
           KQ RITPGF
Sbjct: 151 KQFRITPGF 159
>XP_006716142
          Length = 4927

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KQVRITPGF 9
           KQ RITPGF
Sbjct: 152 KQFRITPGF 160
>XP_005250088
          Length = 4928

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KQVRITPGF 9
           KQ RITPGF
Sbjct: 152 KQFRITPGF 160
>XP_006716141
          Length = 4959

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KQVRITPGF 9
           KQ RITPGF
Sbjct: 152 KQFRITPGF 160
>XP_005250085
          Length = 4979

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KQVRITPGF 9
           KQ RITPGF
Sbjct: 152 KQFRITPGF 160
>XP_006716140
          Length = 4982

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KQVRITPGF 9
           KQ RITPGF
Sbjct: 152 KQFRITPGF 160
>XP_005250084
          Length = 4982

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KQVRITPGF 9
           KQ RITPGF
Sbjct: 152 KQFRITPGF 160
>XP_005250083
          Length = 4982

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KQVRITPGF 9
           KQ RITPGF
Sbjct: 151 KQFRITPGF 159
>XP_005250082
          Length = 4983

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KQVRITPGF 9
           KQ RITPGF
Sbjct: 152 KQFRITPGF 160
>NP_001078823
          Length = 900

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KQVRITPGF 9
           KQVRIT GF
Sbjct: 314 KQVRITFGF 322
>NP_078933
          Length = 937

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KQVRITPGF 9
           KQVRIT GF
Sbjct: 314 KQVRITFGF 322
>XP_006724755
          Length = 532

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KQVRITPGF 9
           KQVRIT GF
Sbjct: 314 KQVRITFGF 322
>XP_006724754
          Length = 815

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KQVRITPGF 9
           KQVRIT GF
Sbjct: 192 KQVRITFGF 200
>XP_005262247
          Length = 845

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KQVRITPGF 9
           KQVRIT GF
Sbjct: 222 KQVRITFGF 230
>NP_001263200
          Length = 572

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KQVRITP 7
           KQVR+TP
Sbjct: 554 KQVRLTP 560
>NP_004587
          Length = 282

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KQVRITPG 8
           K+VR+ PG
Sbjct: 235 KEVRLVPG 242
>NP_001182474
          Length = 275

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KQVRITPG 8
           +QVR+ PG
Sbjct: 173 RQVRLVPG 180
>XP_005252339
          Length = 593

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  QVRITPG 8
          Q+R+TPG
Sbjct: 37 QLRLTPG 43
>NP_937863
          Length = 225

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KQVRITPG 8
           K+VR+ PG
Sbjct: 178 KEVRLVPG 185
>NP_003083
          Length = 225

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KQVRITPG 8
           K+VR+ PG
Sbjct: 178 KEVRLVPG 185
>NP_116198
          Length = 593

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  QVRITPG 8
          Q+R+TPG
Sbjct: 37 QLRLTPG 43
>NP_001438
          Length = 4349

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VRITPGF 9
           VR+TP F
Sbjct: 384 VRVTPAF 390
>NP_001107580
          Length = 569

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VRITPGF 9
           VR+ PGF
Sbjct: 377 VRVCPGF 383
>NP_573439
          Length = 1436

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KQVRITPG 8
          +QVRI PG
Sbjct: 52 EQVRIHPG 59
>NP_573438
          Length = 1440

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KQVRITPG 8
          +QVRI PG
Sbjct: 52 EQVRIHPG 59
>NP_001181930
          Length = 1433

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KQVRITPG 8
          +QVRI PG
Sbjct: 52 EQVRIHPG 59
>NP_005695
          Length = 1446

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KQVRITPG 8
          +QVRI PG
Sbjct: 52 EQVRIHPG 59
>XP_006723819
          Length = 614

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VRITPGF 9
           +RI PGF
Sbjct: 255 IRIIPGF 261
>XP_006714824
          Length = 4349

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VRITPGF 9
           VR+TP F
Sbjct: 384 VRVTPAF 390
>XP_006710334
          Length = 1292

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KQVRITPG 8
          +QVRI PG
Sbjct: 52 EQVRIHPG 59
>XP_006710333
          Length = 1439

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KQVRITPG 8
          +QVRI PG
Sbjct: 52 EQVRIHPG 59
>XP_006710332
          Length = 1442

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  KQVRITPG 8
          +QVRI PG
Sbjct: 52 EQVRIHPG 59
>NP_006781
          Length = 498

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KQVRITPGF 9
           KQ+R+ P F
Sbjct: 452 KQLRVRPTF 460
>NP_001129412
          Length = 314

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KQVRITPGF 9
           KQ+R+ P F
Sbjct: 268 KQLRVRPTF 276
>NP_001004334
          Length = 2367

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KQVRITPGF 9
           +QVR++P F
Sbjct: 225 QQVRLSPPF 233
>NP_006030
          Length = 1479

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  QVRITP 7
          QVR+TP
Sbjct: 61 QVRVTP 66
>NP_001139373
          Length = 520

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KQVRITPG 8
           +QVR+ PG
Sbjct: 130 QQVRLDPG 137
>NP_705618
          Length = 1391

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VRITPGF 9
           VR+ PGF
Sbjct: 390 VRLPPGF 396
>NP_004289
          Length = 1332

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VRITPGF 9
           VR+ PGF
Sbjct: 331 VRLPPGF 337
>NP_001265241
          Length = 1327

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VRITPGF 9
           VR+ PGF
Sbjct: 390 VRLPPGF 396
>XP_005262550
          Length = 699

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  KQVRITPG 8
          KQV++ PG
Sbjct: 65 KQVKMDPG 72
>XP_005272186
          Length = 383

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   KQVRITPGF 9
           KQ+R+ P F
Sbjct: 337 KQLRVRPTF 345
>NP_997244
          Length = 3169

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    KQVRITPG 8
            KQV+  PG
Sbjct: 1824 KQVQFNPG 1831
>NP_001186226
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KQVRITPG 8
           KQV + PG
Sbjct: 697 KQVTVQPG 704
>NP_001129477
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  KQVRITPG 8
          KQV + PG
Sbjct: 28 KQVLVAPG 35
>NP_057374
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KQVRITPG 8
           KQV + PG
Sbjct: 697 KQVTVQPG 704
>NP_001129478
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  KQVRITPG 8
          KQV + PG
Sbjct: 28 KQVLVAPG 35
>NP_006681
          Length = 645

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   KQVRITPGF 9
           K+V + PG+
Sbjct: 452 KEVTVEPGY 460
>NP_997213
          Length = 410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  QVRITPG 8
          QVR+ PG
Sbjct: 4  QVRLPPG 10
>NP_000810
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  KQVRITPG 8
          KQV + PG
Sbjct: 28 KQVLVAPG 35
>NP_112598
          Length = 5088

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1    KQVRITPG 8
            +  R+TPG
Sbjct: 2436 RDARVTPG 2443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1    KQVRITPG 8
            +  R+TPG
Sbjct: 2972 RDARVTPG 2979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1    KQVRITPG 8
            +  R+TPG
Sbjct: 3503 RDARVTPG 3510

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1    KQVRITPG 8
            +  R+TPG
Sbjct: 4037 RDARVTPG 4044
>NP_001186227
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KQVRITPG 8
           KQV + PG
Sbjct: 697 KQVTVQPG 704
>XP_006724053
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  KQVRITPG 8
          KQV + PG
Sbjct: 28 KQVLVAPG 35
>XP_006724052
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  KQVRITPG 8
          KQV + PG
Sbjct: 28 KQVLVAPG 35
>XP_005260998
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  KQVRITPG 8
          KQV + PG
Sbjct: 28 KQVLVAPG 35
>XP_006724051
          Length = 1026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  KQVRITPG 8
          KQV + PG
Sbjct: 44 KQVLVAPG 51
>XP_005256913
          Length = 173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   KQVRITPG 8
           +Q+R +PG
Sbjct: 154 RQIRASPG 161
>XP_005265993
          Length = 349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KQVRITPG 8
           KQV + PG
Sbjct: 327 KQVTVQPG 334
>XP_006714937
          Length = 416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KQVRITPG 8
           KQV + PG
Sbjct: 394 KQVTVQPG 401
>XP_005265992
          Length = 416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KQVRITPG 8
           KQV + PG
Sbjct: 394 KQVTVQPG 401
>XP_005265991
          Length = 416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KQVRITPG 8
           KQV + PG
Sbjct: 394 KQVTVQPG 401
>XP_005265990
          Length = 438

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KQVRITPG 8
           KQV + PG
Sbjct: 416 KQVTVQPG 423
>XP_005265989
          Length = 438

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KQVRITPG 8
           KQV + PG
Sbjct: 416 KQVTVQPG 423
>XP_006714936
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KQVRITPG 8
           KQV + PG
Sbjct: 531 KQVTVQPG 538
>XP_006714935
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KQVRITPG 8
           KQV + PG
Sbjct: 531 KQVTVQPG 538
>XP_005265988
          Length = 620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KQVRITPG 8
           KQV + PG
Sbjct: 598 KQVTVQPG 605
>XP_006714934
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KQVRITPG 8
           KQV + PG
Sbjct: 697 KQVTVQPG 704
>XP_005265987
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   KQVRITPG 8
           KQV + PG
Sbjct: 697 KQVTVQPG 704
>NP_780294
          Length = 433

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  KQVRITPG 8
          KQV + PG
Sbjct: 28 KQVLVAPG 35
>NP_981956
          Length = 159

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   KQVRITPG 8
           +Q+R +PG
Sbjct: 140 RQIRASPG 147
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.329    0.147    0.449 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 798,150
Number of extensions: 1039
Number of successful extensions: 73
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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