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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_002515                                                              18    1135
NP_001107228                                                           18    1935
NP_001244918                                                           18    1935
NP_001107227                                                           18    1935
NP_001944                                                              18    1935
NP_001244917                                                           18    1935
NP_006377                                                              17    3301
NP_001091974                                                           17    3301
NP_003144                                                              16    7355
NP_001171549                                                           16    7355
NP_001171550                                                           16    7355
NP_001073990                                                           16    7355
NP_004154                                                              16    7355
NP_001171551                                                           16    7355
NP_001171552                                                           16    7355
XP_006722581                                                           16    7355
XP_005266791                                                           16    7355
XP_005266790                                                           16    7355
XP_006719638                                                           16    7355
XP_006719637                                                           16    7355
XP_006719636                                                           16    7355
NP_005490                                                              15    9605
NP_055847                                                              15    9605
NP_000289                                                              15    9605
NP_006378                                                              15    9605
XP_005258461                                                           15    9605
XP_005258460                                                           15    9605
XP_006723025                                                           15    9605
XP_005266355                                                           15    9605
XP_005266354                                                           15    9605
XP_005266353                                                           15    9605
XP_005266352                                                           15    9605
XP_005245323                                                           15    9605

>NP_002515
          Length = 189

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KQARELAKS 9
           KQA ELAKS
Sbjct: 128 KQAHELAKS 136



>NP_001107228
          Length = 482

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   KQARELAKS 9
           +QARELAK+
Sbjct: 246 EQARELAKT 254



>NP_001244918
          Length = 487

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   KQARELAKS 9
           +QARELAK+
Sbjct: 246 EQARELAKT 254



>NP_001107227
          Length = 482

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   KQARELAKS 9
           +QARELAK+
Sbjct: 246 EQARELAKT 254



>NP_001944
          Length = 482

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   KQARELAKS 9
           +QARELAK+
Sbjct: 246 EQARELAKT 254



>NP_001244917
          Length = 482

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   KQARELAKS 9
           +QARELAK+
Sbjct: 246 EQARELAKT 254



>NP_006377
          Length = 729

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KQARELAK 8
           KQAREL K
Sbjct: 528 KQARELIK 535



>NP_001091974
          Length = 731

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KQARELAK 8
           KQAREL K
Sbjct: 528 KQARELIK 535



>NP_003144
          Length = 847

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KQARELA 7
           KQAREL+
Sbjct: 319 KQARELS 325



>NP_001171549
          Length = 847

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KQARELA 7
           KQAREL+
Sbjct: 319 KQARELS 325



>NP_001171550
          Length = 847

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KQARELA 7
           KQAREL+
Sbjct: 319 KQARELS 325



>NP_001073990
          Length = 507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   QARELAKS 9
           QAR LAKS
Sbjct: 470 QARGLAKS 477



>NP_004154
          Length = 218

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KQARELA 7
           +QARELA
Sbjct: 146 RQARELA 152



>NP_001171551
          Length = 737

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KQARELA 7
           KQAREL+
Sbjct: 209 KQARELS 215



>NP_001171552
          Length = 737

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KQARELA 7
           KQAREL+
Sbjct: 209 KQARELS 215



>XP_006722581
          Length = 182

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KQARELA 7
           +QARELA
Sbjct: 146 RQARELA 152



>XP_005266791
          Length = 218

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KQARELA 7
           +QARELA
Sbjct: 146 RQARELA 152



>XP_005266790
          Length = 218

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KQARELA 7
           +QARELA
Sbjct: 146 RQARELA 152



>XP_006719638
          Length = 847

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KQARELA 7
           KQAREL+
Sbjct: 319 KQARELS 325



>XP_006719637
          Length = 847

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KQARELA 7
           KQAREL+
Sbjct: 319 KQARELS 325



>XP_006719636
          Length = 847

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KQARELA 7
           KQAREL+
Sbjct: 319 KQARELS 325



>NP_005490
          Length = 640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KQARELAKS 9
           KQA + AKS
Sbjct: 557 KQAEDAAKS 565



>NP_055847
          Length = 1447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KQARELAKS 9
           KQA +LAK+
Sbjct: 212 KQAYDLAKA 220



>NP_000289
          Length = 574

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  KQARELAKS 9
          K  R+LAKS
Sbjct: 18 KSQRDLAKS 26



>NP_006378
          Length = 916

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KQAREL 6
           KQAREL
Sbjct: 228 KQAREL 233



>XP_005258461
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KQARELAKS 9
           KQA + AKS
Sbjct: 461 KQAEDAAKS 469



>XP_005258460
          Length = 588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KQARELAKS 9
           KQA + AKS
Sbjct: 505 KQAEDAAKS 513



>XP_006723025
          Length = 612

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KQARELAKS 9
           KQA + AKS
Sbjct: 529 KQAEDAAKS 537



>XP_005266355
          Length = 1448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KQARELAKS 9
           KQA +LAK+
Sbjct: 212 KQAYDLAKA 220



>XP_005266354
          Length = 1411

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KQARELAKS 9
           KQA +LAK+
Sbjct: 212 KQAYDLAKA 220



>XP_005266353
          Length = 1445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KQARELAKS 9
           KQA +LAK+
Sbjct: 212 KQAYDLAKA 220



>XP_005266352
          Length = 1446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KQARELAKS 9
           KQA +LAK+
Sbjct: 212 KQAYDLAKA 220



>XP_005245323
          Length = 627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  KQARELAKS 9
          K  R+LAKS
Sbjct: 71 KSQRDLAKS 79



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.297    0.107    0.237 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 312,164
Number of extensions: 349
Number of successful extensions: 33
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 33
Number of HSP's successfully gapped: 33
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)