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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              19     869
XP_005262424                                                           19     869
NP_653271                                                              18    1935
NP_001269353                                                           18    1935
NP_036547                                                              17    2528
NP_001192192                                                           17    2528
NP_001244163                                                           17    4312
NP_001244166                                                           17    4312
NP_001244159                                                           17    4312
NP_001244160                                                           17    4312
NP_001093392                                                           17    4312
XP_006724767                                                           17    4312
XP_006724766                                                           17    4312
XP_006724765                                                           17    4312
XP_006724763                                                           17    4312
XP_006724762                                                           17    4312
XP_006724761                                                           17    4312
XP_006724760                                                           17    4312
XP_006724759                                                           17    4312
XP_006724758                                                           17    4312
XP_006724757                                                           17    4312
XP_006724756                                                           17    4312
NP_001161354                                                           16    5631
NP_065070                                                              16    5631
NP_056250                                                              16    7355
NP_001267468                                                           16    7355
NP_904355                                                              16    7355
XP_005250911                                                           16    7355
XP_005250910                                                           16    7355
NP_705838                                                              15    9605
NP_078966                                                              15    9605
XP_006723004                                                           15    9605
XP_006710300                                                           15    9605

>NP_722576
          Length = 3080

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KNSAVSTTS 9
           KNS VSTTS
Sbjct: 381 KNSVVSTTS 389



>XP_005262424
          Length = 2875

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KNSAVSTTS 9
           KNS VSTTS
Sbjct: 176 KNSVVSTTS 184



>NP_653271
          Length = 1454

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    KNSAVSTTS 9
            KNSA STT+
Sbjct: 1125 KNSATSTTN 1133



>NP_001269353
          Length = 963

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   KNSAVSTTS 9
           KNSA STT+
Sbjct: 634 KNSATSTTN 642



>NP_036547
          Length = 910

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KNSAVSTTS 9
           KNSA+ TT+
Sbjct: 437 KNSAIKTTT 445



>NP_001192192
          Length = 726

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KNSAVSTTS 9
           KNSA+ TT+
Sbjct: 253 KNSAIKTTT 261



>NP_001244163
          Length = 954

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSAVSTTS 9
           N A+STTS
Sbjct: 767 NQAISTTS 774



>NP_001244166
          Length = 954

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSAVSTTS 9
           N A+STTS
Sbjct: 767 NQAISTTS 774



>NP_001244159
          Length = 954

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSAVSTTS 9
           N A+STTS
Sbjct: 767 NQAISTTS 774



>NP_001244160
          Length = 1059

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSAVSTTS 9
           N A+STTS
Sbjct: 793 NQAISTTS 800



>NP_001093392
          Length = 1137

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSAVSTTS 9
           N A+STTS
Sbjct: 871 NQAISTTS 878



>XP_006724767
          Length = 641

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSAVSTTS 9
           N A+STTS
Sbjct: 375 NQAISTTS 382



>XP_006724766
          Length = 645

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSAVSTTS 9
           N A+STTS
Sbjct: 379 NQAISTTS 386



>XP_006724765
          Length = 652

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSAVSTTS 9
           N A+STTS
Sbjct: 386 NQAISTTS 393



>XP_006724763
          Length = 901

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSAVSTTS 9
           N A+STTS
Sbjct: 871 NQAISTTS 878



>XP_006724762
          Length = 903

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSAVSTTS 9
           N A+STTS
Sbjct: 871 NQAISTTS 878



>XP_006724761
          Length = 1033

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSAVSTTS 9
           N A+STTS
Sbjct: 767 NQAISTTS 774



>XP_006724760
          Length = 1033

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSAVSTTS 9
           N A+STTS
Sbjct: 767 NQAISTTS 774



>XP_006724759
          Length = 1033

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSAVSTTS 9
           N A+STTS
Sbjct: 767 NQAISTTS 774



>XP_006724758
          Length = 1058

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSAVSTTS 9
           N A+STTS
Sbjct: 871 NQAISTTS 878



>XP_006724757
          Length = 1080

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSAVSTTS 9
           N A+STTS
Sbjct: 814 NQAISTTS 821



>XP_006724756
          Length = 1124

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSAVSTTS 9
           N A+STTS
Sbjct: 858 NQAISTTS 865



>NP_001161354
          Length = 1250

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KNSAVSTTS 9
            KNS++ TTS
Sbjct: 1009 KNSSLRTTS 1017



>NP_065070
          Length = 1429

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KNSAVSTTS 9
            KNS++ TTS
Sbjct: 1188 KNSSLRTTS 1196



>NP_056250
          Length = 838

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSAVSTTS 9
           N+AV TTS
Sbjct: 486 NTAVDTTS 493



>NP_001267468
          Length = 838

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSAVSTTS 9
           N+AV TTS
Sbjct: 486 NTAVDTTS 493



>NP_904355
          Length = 838

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSAVSTTS 9
           N+AV TTS
Sbjct: 486 NTAVDTTS 493



>XP_005250911
          Length = 528

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSAVSTTS 9
           N+AV TTS
Sbjct: 176 NTAVDTTS 183



>XP_005250910
          Length = 838

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NSAVSTTS 9
           N+AV TTS
Sbjct: 486 NTAVDTTS 493



>NP_705838
          Length = 4069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    NSAVSTT 8
            NSA STT
Sbjct: 3716 NSATSTT 3722



>NP_078966
          Length = 14507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2     NSAVSTTS 9
             +SAVSTT+
Sbjct: 11530 SSAVSTTT 11537



>XP_006723004
          Length = 6443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    NSAVSTTS 9
            +SAVSTT+
Sbjct: 3444 SSAVSTTT 3451



>XP_006710300
          Length = 1116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   NSAVSTT 8
           NSA++TT
Sbjct: 879 NSAITTT 885



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.271   0.0826    0.174 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 288,049
Number of extensions: 489
Number of successful extensions: 33
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 33
Number of HSP's successfully gapped: 33
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.5 bits)
S2: 28 (15.4 bits)