Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              20     390
XP_006716142                                                           20     390
XP_005250088                                                           20     390
XP_006716141                                                           20     390
XP_005250085                                                           20     390
XP_006716140                                                           20     390
XP_005250084                                                           20     390
XP_005250083                                                           20     390
XP_005250082                                                           20     390
NP_002513                                                              17    3301
NP_079092                                                              17    4312
NP_072047                                                              16    5631
NP_001276103                                                           16    5631
NP_001276105                                                           16    5631
NP_001276104                                                           16    5631
NP_055520                                                              16    5631
XP_006726169                                                           16    5631
XP_006726075                                                           16    5631
XP_006725982                                                           16    5631
XP_006725773                                                           16    5631
XP_006725559                                                           16    5631
XP_006716252                                                           16    5631
XP_006716251                                                           16    5631
XP_006715227                                                           16    5631
NP_001191111                                                           16    7355
NP_001191112                                                           16    7355
NP_002488                                                              16    7355
NP_001139281                                                           16    7355
NP_002514                                                              16    7355
NP_001070654                                                           16    7355
NP_004770                                                              16    7355
NP_079005                                                              16    7355
XP_006723449                                                           16    7355
XP_005268585                                                           16    7355
XP_005268584                                                           16    7355
XP_005268583                                                           16    7355
XP_005273204                                                           16    7355
NP_075060                                                              15    9605
NP_001138570                                                           15    9605
NP_001234937                                                           15    9605
NP_001138569                                                           15    9605
NP_005405                                                              15    9605
NP_689777                                                              15    9605
NP_060360                                                              15    9605
NP_817124                                                              15    9605
NP_006539                                                              15    9605
NP_001007226                                                           15    9605
NP_653305                                                              15    9605
NP_001018070                                                           15    9605
NP_001129523                                                           15    9605
NP_700356                                                              15    9605
NP_078948                                                              15    9605
NP_001243628                                                           15    9605
NP_001004353                                                           15    9605
NP_001243629                                                           15    9605
NP_001243630                                                           15    9605
XP_006726574                                                           15    9605
XP_006717178                                                           15    9605
XP_006717176                                                           15    9605
XP_005250858                                                           15    9605
XP_005250857                                                           15    9605
XP_005263278                                                           15    9605
XP_005263277                                                           15    9605
XP_006713798                                                           15    9605
XP_005247778                                                           15    9605
XP_006713541                                                           15    9605
XP_006713540                                                           15    9605
NP_001139760                                                           15    9605
>NP_733751
          Length = 4911

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KLREIVLQQ 9
            KLREI+LQQ
Sbjct: 2386 KLREIILQQ 2394
>XP_006716142
          Length = 4927

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KLREIVLQQ 9
            KLREI+LQQ
Sbjct: 2403 KLREIILQQ 2411
>XP_005250088
          Length = 4928

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KLREIVLQQ 9
            KLREI+LQQ
Sbjct: 2403 KLREIILQQ 2411
>XP_006716141
          Length = 4959

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KLREIVLQQ 9
            KLREI+LQQ
Sbjct: 2403 KLREIILQQ 2411
>XP_005250085
          Length = 4979

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KLREIVLQQ 9
            KLREI+LQQ
Sbjct: 2403 KLREIILQQ 2411
>XP_006716140
          Length = 4982

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KLREIVLQQ 9
            KLREI+LQQ
Sbjct: 2403 KLREIILQQ 2411
>XP_005250084
          Length = 4982

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KLREIVLQQ 9
            KLREI+LQQ
Sbjct: 2403 KLREIILQQ 2411
>XP_005250083
          Length = 4982

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KLREIVLQQ 9
            KLREI+LQQ
Sbjct: 2402 KLREIILQQ 2410
>XP_005250082
          Length = 4983

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    KLREIVLQQ 9
            KLREI+LQQ
Sbjct: 2403 KLREIILQQ 2411
>NP_002513
          Length = 432

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  KLREIVLQQ 9
          +LRE VLQQ
Sbjct: 60 QLRETVLQQ 68
>NP_079092
          Length = 569

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   KLREIVL 7
           KLREIVL
Sbjct: 151 KLREIVL 157
>NP_072047
          Length = 723

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLREIVLQQ 9
           K+RE +LQ+
Sbjct: 237 KIREFILQK 245
>NP_001276103
          Length = 656

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLREIVLQQ 9
           K+RE +LQ+
Sbjct: 170 KIREFILQK 178
>NP_001276105
          Length = 534

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLREIVLQQ 9
           K+RE +LQ+
Sbjct: 112 KIREFILQK 120
>NP_001276104
          Length = 598

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLREIVLQQ 9
           K+RE +LQ+
Sbjct: 112 KIREFILQK 120
>NP_055520
          Length = 1966

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    KLREIVLQQ 9
            +LRE++L+Q
Sbjct: 1542 RLRELMLEQ 1550
>XP_006726169
          Length = 396

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLREIVLQQ 9
           K+RE +LQ+
Sbjct: 237 KIREFILQK 245
>XP_006726075
          Length = 396

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLREIVLQQ 9
           K+RE +LQ+
Sbjct: 237 KIREFILQK 245
>XP_006725982
          Length = 396

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLREIVLQQ 9
           K+RE +LQ+
Sbjct: 237 KIREFILQK 245
>XP_006725773
          Length = 396

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLREIVLQQ 9
           K+RE +LQ+
Sbjct: 237 KIREFILQK 245
>XP_006725559
          Length = 396

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLREIVLQQ 9
           K+RE +LQ+
Sbjct: 237 KIREFILQK 245
>XP_006716252
          Length = 1937

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    KLREIVLQQ 9
            +LRE++L+Q
Sbjct: 1551 RLRELMLEQ 1559
>XP_006716251
          Length = 1975

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    KLREIVLQQ 9
            +LRE++L+Q
Sbjct: 1551 RLRELMLEQ 1559
>XP_006715227
          Length = 396

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLREIVLQQ 9
           K+RE +LQ+
Sbjct: 237 KIREFILQK 245
>NP_001191111
          Length = 388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLREIVLQQ 9
           KL+EI LQ+
Sbjct: 307 KLKEIQLQE 315
>NP_001191112
          Length = 384

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLREIVLQQ 9
           KL+EI LQ+
Sbjct: 307 KLKEIQLQE 315
>NP_002488
          Length = 445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLREIVLQQ 9
           KL+EI LQ+
Sbjct: 307 KLKEIQLQE 315
>NP_001139281
          Length = 2036

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KLREIVLQ 8
            +L+E+VLQ
Sbjct: 1908 RLKEVVLQ 1915
>NP_002514
          Length = 431

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  KLREIVLQQ 9
          +LRE V+QQ
Sbjct: 65 QLRETVVQQ 73
>NP_001070654
          Length = 2003

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KLREIVLQ 8
            +L+E+VLQ
Sbjct: 1875 RLKEVVLQ 1882
>NP_004770
          Length = 292

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  KLREIVL 7
          K+REIVL
Sbjct: 26 KIREIVL 32
>NP_079005
          Length = 1995

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KLREIVLQ 8
            +L+E+VLQ
Sbjct: 1867 RLKEVVLQ 1874
>XP_006723449
          Length = 2003

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KLREIVLQ 8
            +L+E+VLQ
Sbjct: 1875 RLKEVVLQ 1882
>XP_005268585
          Length = 238

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  KLREIVL 7
          K+REIVL
Sbjct: 26 KIREIVL 32
>XP_005268584
          Length = 238

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  KLREIVL 7
          K+REIVL
Sbjct: 26 KIREIVL 32
>XP_005268583
          Length = 292

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  KLREIVL 7
          K+REIVL
Sbjct: 26 KIREIVL 32
>XP_005273204
          Length = 437

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KLREIVLQQ 9
           KL+EI LQ+
Sbjct: 307 KLKEIQLQE 315
>NP_075060
          Length = 247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LREIVLQ 8
           L+EIVLQ
Sbjct: 233 LKEIVLQ 239
>NP_001138570
          Length = 664

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LREIVLQQ 9
           LRE  LQQ
Sbjct: 155 LREFTLQQ 162
>NP_001234937
          Length = 684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LREIVLQQ 9
           LRE  LQQ
Sbjct: 175 LREFTLQQ 182
>NP_001138569
          Length = 638

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LREIVLQQ 9
           LRE  LQQ
Sbjct: 175 LREFTLQQ 182
>NP_005405
          Length = 684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LREIVLQQ 9
           LRE  LQQ
Sbjct: 175 LREFTLQQ 182
>NP_689777
          Length = 3997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KLREIVLQ 8
            KLR++V+Q
Sbjct: 3559 KLRKLVIQ 3566
>NP_060360
          Length = 4022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KLREIVLQ 8
            KLR++V+Q
Sbjct: 3584 KLRKLVIQ 3591
>NP_817124
          Length = 444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2 LREIVLQQ 9
         +REIVL Q
Sbjct: 1 MREIVLTQ 8
>NP_006539
          Length = 599

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KLREIVLQ 8
           K+REIV Q
Sbjct: 574 KIREIVQQ 581
>NP_001007226
          Length = 556

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KLREIVLQ 8
           K+REIV Q
Sbjct: 531 KIREIVQQ 538
>NP_653305
          Length = 605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLREIVLQ 8
           KL+E+VL+
Sbjct: 406 KLKEVVLK 413
>NP_001018070
          Length = 598

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLREIVLQ 8
           KL+E+VL+
Sbjct: 406 KLKEVVLK 413
>NP_001129523
          Length = 1059

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KLREIVLQ 8
           KLR ++LQ
Sbjct: 327 KLRRLILQ 334
>NP_700356
          Length = 1119

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KLREIVLQ 8
           KLR ++LQ
Sbjct: 387 KLRRLILQ 394
>NP_078948
          Length = 903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KLREIVLQQ 9
           K RE+ LQQ
Sbjct: 793 KQRELYLQQ 801
>NP_001243628
          Length = 386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LREIVLQQ 9
          LRE++L+Q
Sbjct: 86 LRELLLEQ 93
>NP_001004353
          Length = 308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LREIVLQQ 9
          LRE++L+Q
Sbjct: 86 LRELLLEQ 93
>NP_001243629
          Length = 331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LREIVLQQ 9
          LRE++L+Q
Sbjct: 86 LRELLLEQ 93
>NP_001243630
          Length = 253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LREIVLQQ 9
          LRE++L+Q
Sbjct: 86 LRELLLEQ 93
>XP_006726574
          Length = 446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KLREIVLQQ 9
           +LRE+ LQ+
Sbjct: 119 RLREMALQE 127
>XP_006717178
          Length = 327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LREIVLQQ 9
          LRE++L+Q
Sbjct: 86 LRELLLEQ 93
>XP_006717176
          Length = 386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LREIVLQQ 9
          LRE++L+Q
Sbjct: 86 LRELLLEQ 93
>XP_005250858
          Length = 4022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KLREIVLQ 8
            KLR++V+Q
Sbjct: 3584 KLRKLVIQ 3591
>XP_005250857
          Length = 4022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    KLREIVLQ 8
            KLR++V+Q
Sbjct: 3584 KLRKLVIQ 3591
>XP_005263278
          Length = 620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KLREIVLQQ 9
           K RE+ LQQ
Sbjct: 510 KQRELYLQQ 518
>XP_005263277
          Length = 759

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KLREIVLQQ 9
           K RE+ LQQ
Sbjct: 649 KQRELYLQQ 657
>XP_006713798
          Length = 684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LREIVLQQ 9
           LRE  LQQ
Sbjct: 175 LREFTLQQ 182
>XP_005247778
          Length = 684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LREIVLQQ 9
           LRE  LQQ
Sbjct: 175 LREFTLQQ 182
>XP_006713541
          Length = 300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KLREIVLQ 8
           K+REIV Q
Sbjct: 275 KIREIVQQ 282
>XP_006713540
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KLREIVLQ 8
           K+REIV Q
Sbjct: 318 KIREIVQQ 325
>NP_001139760
          Length = 604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KLREIVLQ 8
           KL+E+VL+
Sbjct: 412 KLKEVVLK 419
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.142    0.334 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 459,595
Number of extensions: 981
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package