Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              17    2528
XP_006716142                                                           17    2528
XP_005250088                                                           17    2528
XP_006716141                                                           17    2528
XP_005250085                                                           17    2528
XP_006716140                                                           17    2528
XP_005250084                                                           17    2528
XP_005250083                                                           17    2528
XP_005250082                                                           17    2528
NP_002345                                                              16    5631
NP_001138732                                                           15    9605
NP_005428                                                              15    9605
NP_001138735                                                           15    9605
NP_001138733                                                           15    9605
NP_001138734                                                           15    9605
NP_115690                                                              15    9605
XP_006719702                                                           15    9605
NP_076943                                                              15    9605
>NP_733751
          Length = 4911

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KLKSGIVAV 9
           KLKSGI AV
Sbjct: 911 KLKSGIGAV 919
>XP_006716142
          Length = 4927

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KLKSGIVAV 9
           KLKSGI AV
Sbjct: 912 KLKSGIGAV 920
>XP_005250088
          Length = 4928

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KLKSGIVAV 9
           KLKSGI AV
Sbjct: 912 KLKSGIGAV 920
>XP_006716141
          Length = 4959

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KLKSGIVAV 9
           KLKSGI AV
Sbjct: 912 KLKSGIGAV 920
>XP_005250085
          Length = 4979

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KLKSGIVAV 9
           KLKSGI AV
Sbjct: 912 KLKSGIGAV 920
>XP_006716140
          Length = 4982

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KLKSGIVAV 9
           KLKSGI AV
Sbjct: 912 KLKSGIGAV 920
>XP_005250084
          Length = 4982

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KLKSGIVAV 9
           KLKSGI AV
Sbjct: 912 KLKSGIGAV 920
>XP_005250083
          Length = 4982

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KLKSGIVAV 9
           KLKSGI AV
Sbjct: 911 KLKSGIGAV 919
>XP_005250082
          Length = 4983

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   KLKSGIVAV 9
           KLKSGI AV
Sbjct: 912 KLKSGIGAV 920
>NP_002345
          Length = 314

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LKSGIVAV 9
           LK+G++AV
Sbjct: 264 LKAGVIAV 271
>NP_001138732
          Length = 650

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KLKSGIVAV 9
           K  SGIVAV
Sbjct: 207 KSASGIVAV 215
>NP_005428
          Length = 614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KLKSGIVAV 9
           K  SGIVAV
Sbjct: 191 KSASGIVAV 199
>NP_001138735
          Length = 614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KLKSGIVAV 9
           K  SGIVAV
Sbjct: 191 KSASGIVAV 199
>NP_001138733
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KLKSGIVAV 9
           K  SGIVAV
Sbjct: 207 KSASGIVAV 215
>NP_001138734
          Length = 614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KLKSGIVAV 9
           K  SGIVAV
Sbjct: 191 KSASGIVAV 199
>NP_115690
          Length = 327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LKSGIVAV 9
           L SGIVA+
Sbjct: 314 LTSGIVAI 321
>XP_006719702
          Length = 246

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LKSGIVAV 9
           L SGIVA+
Sbjct: 233 LTSGIVAI 240
>NP_076943
          Length = 176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LKSGIVA 8
           LK+GIVA
Sbjct: 127 LKTGIVA 133
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.317    0.135    0.325 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 429,025
Number of extensions: 510
Number of successful extensions: 18
Number of sequences better than 10000.0: 18
Number of HSP's gapped: 18
Number of HSP's successfully gapped: 18
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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