Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005148                                                              19     665
NP_009297                                                              19     665
NP_001124193                                                           17    4312
NP_076995                                                              17    4312
NP_001278327                                                           16    7355
NP_001005751                                                           16    7355
NP_004870                                                              16    7355
NP_001277064                                                           16    7355
NP_001162578                                                           16    7355
NP_919301                                                              16    7355
NP_060557                                                              16    7355
XP_006717895                                                           16    7355
XP_005269865                                                           16    7355
XP_006717894                                                           16    7355
XP_005269864                                                           16    7355
XP_005269863                                                           16    7355
XP_006710825                                                           16    7355
NP_001162023                                                           16    7355
NP_001162577                                                           16    7355
NP_056077                                                              16    7355
NP_004296                                                              15    9605
NP_647596                                                              15    9605
NP_003757                                                              15    9605
NP_001005207                                                           15    9605
NP_036221                                                              15    9605
NP_653267                                                              15    9605
NP_056109                                                              15    9605
NP_056013                                                              15    9605
NP_001274365                                                           15    9605
NP_957518                                                              15    9605
XP_005276311                                                           15    9605
XP_005257817                                                           15    9605
XP_005257816                                                           15    9605
XP_005257815                                                           15    9605
XP_005257447                                                           15    9605
XP_005257446                                                           15    9605
XP_005257445                                                           15    9605
XP_005257444                                                           15    9605
XP_005257443                                                           15    9605
XP_005257442                                                           15    9605
XP_005271814                                                           15    9605
XP_005271813                                                           15    9605
XP_006715738                                                           15    9605
XP_005271812                                                           15    9605
XP_005271810                                                           15    9605
XP_005271809                                                           15    9605
XP_005271808                                                           15    9605
XP_005271807                                                           15    9605
XP_005263447                                                           15    9605
XP_005263704                                                           15    9605
XP_006712496                                                           15    9605
XP_006712495                                                           15    9605
XP_006712494                                                           15    9605
XP_006712492                                                           15    9605
XP_006712491                                                           15    9605
XP_005263702                                                           15    9605
XP_006712489                                                           15    9605
XP_006712488                                                           15    9605
XP_005263700                                                           15    9605
XP_006712487                                                           15    9605
XP_005263699                                                           15    9605
XP_006711818                                                           15    9605
XP_006711817                                                           15    9605
NP_057439                                                              15    9605
>NP_005148
          Length = 1130

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KKTSLFSAL 9
           KKT+LFSAL
Sbjct: 595 KKTNLFSAL 603
>NP_009297
          Length = 1149

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KKTSLFSAL 9
           KKT+LFSAL
Sbjct: 614 KKTNLFSAL 622
>NP_001124193
          Length = 265

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  KKTSLFSAL 9
          KK+ LFSAL
Sbjct: 31 KKSFLFSAL 39
>NP_076995
          Length = 265

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  KKTSLFSAL 9
          KK+ LFSAL
Sbjct: 31 KKSFLFSAL 39
>NP_001278327
          Length = 1320

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KKTSLF 6
           KKTSLF
Sbjct: 660 KKTSLF 665
>NP_001005751
          Length = 1341

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KKTSLF 6
           KKTSLF
Sbjct: 660 KKTSLF 665
>NP_004870
          Length = 340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TSLFSAL 9
           TS+FSAL
Sbjct: 123 TSIFSAL 129
>NP_001277064
          Length = 326

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TSLFSAL 9
           TS+FSAL
Sbjct: 109 TSIFSAL 115
>NP_001162578
          Length = 1245

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KKTSLF 6
           KKTSLF
Sbjct: 636 KKTSLF 641
>NP_919301
          Length = 603

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   KKTSLFS 7
           KK+SLFS
Sbjct: 223 KKSSLFS 229
>NP_060557
          Length = 674

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KTSLFSA 8
           KTSLFS+
Sbjct: 430 KTSLFSS 436
>XP_006717895
          Length = 1297

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KKTSLF 6
           KKTSLF
Sbjct: 688 KKTSLF 693
>XP_005269865
          Length = 1331

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KKTSLF 6
           KKTSLF
Sbjct: 712 KKTSLF 717
>XP_006717894
          Length = 1342

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KKTSLF 6
           KKTSLF
Sbjct: 712 KKTSLF 717
>XP_005269864
          Length = 1364

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KKTSLF 6
           KKTSLF
Sbjct: 683 KKTSLF 688
>XP_005269863
          Length = 1369

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KKTSLF 6
           KKTSLF
Sbjct: 688 KKTSLF 693
>XP_006710825
          Length = 669

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KTSLFSA 8
           KTSLFS+
Sbjct: 425 KTSLFSS 431
>NP_001162023
          Length = 634

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KTSLFSA 8
           KTSLFS+
Sbjct: 390 KTSLFSS 396
>NP_001162577
          Length = 1279

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KKTSLF 6
           KKTSLF
Sbjct: 660 KKTSLF 665
>NP_056077
          Length = 1320

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KKTSLF 6
           KKTSLF
Sbjct: 660 KKTSLF 665
>NP_004296
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KKTSLFSAL 9
           KK+ LFS L
Sbjct: 256 KKSKLFSRL 264
>NP_647596
          Length = 497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KKTSLFSAL 9
           KK+ LFS L
Sbjct: 256 KKSKLFSRL 264
>NP_003757
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KKTSLFSA 8
           KKT++F+A
Sbjct: 265 KKTNVFNA 272
>NP_001005207
          Length = 964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KTSLFSA 8
           +TSLFSA
Sbjct: 710 QTSLFSA 716
>NP_036221
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KTSLFSAL 9
           +TSLFS++
Sbjct: 248 RTSLFSSI 255
>NP_653267
          Length = 4753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    KKTSLFSAL 9
            ++TSL SAL
Sbjct: 1566 RQTSLLSAL 1574
>NP_056109
          Length = 964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KTSLFSA 8
           +TSLFSA
Sbjct: 710 QTSLFSA 716
>NP_056013
          Length = 1261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KKTSLFSAL 9
            K TSL SAL
Sbjct: 1105 KDTSLHSAL 1113
>NP_001274365
          Length = 1271

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KKTSLFSAL 9
            K TSL SAL
Sbjct: 1162 KDTSLHSAL 1170
>NP_957518
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KKTSLFSA 8
           +KT LFSA
Sbjct: 199 RKTFLFSA 206
>XP_005276311
          Length = 232

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KKTSLFSAL 9
           +KT++FS L
Sbjct: 151 QKTTIFSTL 159
>XP_005257817
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KKTSLFSA 8
           KKT++F+A
Sbjct: 265 KKTNVFNA 272
>XP_005257816
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KKTSLFSA 8
           KKT++F+A
Sbjct: 265 KKTNVFNA 272
>XP_005257815
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   KKTSLFSA 8
           KKT++F+A
Sbjct: 265 KKTNVFNA 272
>XP_005257447
          Length = 925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KTSLFSA 8
           +TSLFSA
Sbjct: 710 QTSLFSA 716
>XP_005257446
          Length = 925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KTSLFSA 8
           +TSLFSA
Sbjct: 710 QTSLFSA 716
>XP_005257445
          Length = 930

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KTSLFSA 8
           +TSLFSA
Sbjct: 710 QTSLFSA 716
>XP_005257444
          Length = 930

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KTSLFSA 8
           +TSLFSA
Sbjct: 676 QTSLFSA 682
>XP_005257443
          Length = 939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KTSLFSA 8
           +TSLFSA
Sbjct: 676 QTSLFSA 682
>XP_005257442
          Length = 973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KTSLFSA 8
           +TSLFSA
Sbjct: 710 QTSLFSA 716
>XP_005271814
          Length = 1047

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   KKTSLFSAL 9
           K TSL SAL
Sbjct: 891 KDTSLHSAL 899
>XP_005271813
          Length = 1214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KKTSLFSAL 9
            K TSL SAL
Sbjct: 1105 KDTSLHSAL 1113
>XP_006715738
          Length = 1229

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KKTSLFSAL 9
            K TSL SAL
Sbjct: 1120 KDTSLHSAL 1128
>XP_005271812
          Length = 1245

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KKTSLFSAL 9
            K TSL SAL
Sbjct: 1177 KDTSLHSAL 1185
>XP_005271810
          Length = 1276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KKTSLFSAL 9
            K TSL SAL
Sbjct: 1120 KDTSLHSAL 1128
>XP_005271809
          Length = 1286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KKTSLFSAL 9
            K TSL SAL
Sbjct: 1177 KDTSLHSAL 1185
>XP_005271808
          Length = 1318

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KKTSLFSAL 9
            K TSL SAL
Sbjct: 1162 KDTSLHSAL 1170
>XP_005271807
          Length = 1333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    KKTSLFSAL 9
            K TSL SAL
Sbjct: 1177 KDTSLHSAL 1185
>XP_005263447
          Length = 232

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   KKTSLFSAL 9
           +KT++FS L
Sbjct: 151 QKTTIFSTL 159
>XP_005263704
          Length = 424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KKTSLFSAL 9
           KK+ LFS L
Sbjct: 256 KKSKLFSRL 264
>XP_006712496
          Length = 455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KKTSLFSAL 9
           KK+ LFS L
Sbjct: 287 KKSKLFSRL 295
>XP_006712495
          Length = 485

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KKTSLFSAL 9
           KK+ LFS L
Sbjct: 287 KKSKLFSRL 295
>XP_006712494
          Length = 498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KKTSLFSAL 9
           KK+ LFS L
Sbjct: 287 KKSKLFSRL 295
>XP_006712492
          Length = 521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KKTSLFSAL 9
           KK+ LFS L
Sbjct: 287 KKSKLFSRL 295
>XP_006712491
          Length = 528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KKTSLFSAL 9
           KK+ LFS L
Sbjct: 287 KKSKLFSRL 295
>XP_005263702
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KKTSLFSAL 9
           KK+ LFS L
Sbjct: 232 KKSKLFSRL 240
>XP_006712489
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KKTSLFSAL 9
           KK+ LFS L
Sbjct: 287 KKSKLFSRL 295
>XP_006712488
          Length = 564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KKTSLFSAL 9
           KK+ LFS L
Sbjct: 287 KKSKLFSRL 295
>XP_005263700
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KKTSLFSAL 9
           KK+ LFS L
Sbjct: 256 KKSKLFSRL 264
>XP_006712487
          Length = 584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KKTSLFSAL 9
           KK+ LFS L
Sbjct: 263 KKSKLFSRL 271
>XP_005263699
          Length = 608

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KKTSLFSAL 9
           KK+ LFS L
Sbjct: 287 KKSKLFSRL 295
>XP_006711818
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  KTSLFSAL 9
          +TSLFS++
Sbjct: 69 RTSLFSSI 76
>XP_006711817
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  KTSLFSAL 9
          +TSLFS++
Sbjct: 69 RTSLFSSI 76
>NP_057439
          Length = 455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KKTSLFSA 8
           +KT LFSA
Sbjct: 199 RKTFLFSA 206
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.121    0.286 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 343,214
Number of extensions: 534
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package