Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005219                                                              20     390
NP_001276866                                                           20     390
NP_004439                                                              20     390
NP_001276865                                                           20     390
NP_001005862                                                           20     390
XP_005257197                                                           20     390
XP_006721828                                                           20     390
NP_061116                                                              17    4312
NP_000821                                                              16    5631
NP_783300                                                              16    5631
NP_997210                                                              16    5631
NP_000373                                                              16    5631
XP_005261001                                                           16    5631
XP_005261000                                                           16    5631
XP_005260999                                                           16    5631
XP_006724054                                                           16    5631
NP_001026976                                                           16    5631
NP_598375                                                              16    7355
NP_001138648                                                           16    7355
XP_005262773                                                           16    7355
XP_006714140                                                           16    7355
XP_006714139                                                           16    7355
XP_005262771                                                           16    7355
XP_005262770                                                           16    7355
XP_005262769                                                           16    7355
XP_005262768                                                           16    7355
NP_006493                                                              15    9605
NP_789786                                                              15    9605
NP_008870                                                              15    9605
NP_003175                                                              15    9605
XP_005276824                                                           15    9605
XP_005276823                                                           15    9605
XP_005276822                                                           15    9605
XP_006726278                                                           15    9605
XP_005276821                                                           15    9605
XP_006726277                                                           15    9605
XP_005276820                                                           15    9605
XP_005276819                                                           15    9605
XP_005276818                                                           15    9605
XP_005268078                                                           15    9605
XP_006716684                                                           15    9605
XP_006716108                                                           15    9605
XP_006716107                                                           15    9605
XP_006716106                                                           15    9605
XP_005249243                                                           15    9605
XP_005248520                                                           15    9605
XP_005248519                                                           15    9605
XP_005248518                                                           15    9605
XP_006714633                                                           15    9605
XP_005248517                                                           15    9605
XP_006714632                                                           15    9605
XP_005248516                                                           15    9605
XP_005248515                                                           15    9605
XP_005248514                                                           15    9605
>NP_005219
          Length = 1210

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KILDEAYVM 9
           +ILDEAYVM
Sbjct: 758 EILDEAYVM 766
>NP_001276866
          Length = 1055

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KILDEAYVM 9
           +ILDEAYVM
Sbjct: 766 EILDEAYVM 774
>NP_004439
          Length = 1255

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KILDEAYVM 9
           +ILDEAYVM
Sbjct: 766 EILDEAYVM 774
>NP_001276865
          Length = 1240

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KILDEAYVM 9
           +ILDEAYVM
Sbjct: 751 EILDEAYVM 759
>NP_001005862
          Length = 1225

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KILDEAYVM 9
           +ILDEAYVM
Sbjct: 736 EILDEAYVM 744
>XP_005257197
          Length = 1225

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KILDEAYVM 9
           +ILDEAYVM
Sbjct: 736 EILDEAYVM 744
>XP_006721828
          Length = 1336

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   KILDEAYVM 9
           +ILDEAYVM
Sbjct: 847 EILDEAYVM 855
>NP_061116
          Length = 725

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KILDEAYV 8
           K+L EAYV
Sbjct: 371 KLLQEAYV 378
>NP_000821
          Length = 918

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILDEAYVM 9
           IL+E YVM
Sbjct: 454 ILEEPYVM 461
>NP_783300
          Length = 905

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILDEAYVM 9
           IL+E YVM
Sbjct: 439 ILEEPYVM 446
>NP_997210
          Length = 123

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  ILDEAYVM 9
          +L+E+YVM
Sbjct: 39 LLEESYVM 46
>NP_000373
          Length = 485

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  ILDEAYV 8
          +LDEAY+
Sbjct: 91 MLDEAYI 97
>XP_005261001
          Length = 903

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILDEAYVM 9
           IL+E YVM
Sbjct: 439 ILEEPYVM 446
>XP_005261000
          Length = 920

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILDEAYVM 9
           IL+E YVM
Sbjct: 454 ILEEPYVM 461
>XP_005260999
          Length = 934

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILDEAYVM 9
           IL+E YVM
Sbjct: 439 ILEEPYVM 446
>XP_006724054
          Length = 949

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILDEAYVM 9
           IL+E YVM
Sbjct: 454 ILEEPYVM 461
>NP_001026976
          Length = 508

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  ILDEAYV 8
          +LDEAY+
Sbjct: 91 MLDEAYI 97
>NP_598375
          Length = 1101

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KILDEAY 7
           K+L+EAY
Sbjct: 653 KLLEEAY 659
>NP_001138648
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KILDEAYV 8
           K LDEAY+
Sbjct: 328 KDLDEAYL 335
>XP_005262773
          Length = 557

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KILDEAY 7
           K+L+EAY
Sbjct: 109 KLLEEAY 115
>XP_006714140
          Length = 729

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KILDEAY 7
           K+L+EAY
Sbjct: 281 KLLEEAY 287
>XP_006714139
          Length = 950

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KILDEAY 7
           K+L+EAY
Sbjct: 653 KLLEEAY 659
>XP_005262771
          Length = 995

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KILDEAY 7
           K+L+EAY
Sbjct: 547 KLLEEAY 553
>XP_005262770
          Length = 995

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KILDEAY 7
           K+L+EAY
Sbjct: 547 KLLEEAY 553
>XP_005262769
          Length = 1034

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KILDEAY 7
           K+L+EAY
Sbjct: 586 KLLEEAY 592
>XP_005262768
          Length = 1064

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   KILDEAY 7
           K+L+EAY
Sbjct: 616 KLLEEAY 622
>NP_006493
          Length = 713

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LDEAYV 8
           +DEAYV
Sbjct: 114 IDEAYV 119
>NP_789786
          Length = 511

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KILDEAYVM 9
           K  +EAYVM
Sbjct: 314 KSKEEAYVM 322
>NP_008870
          Length = 1332

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KILDEA 6
           KILDEA
Sbjct: 897 KILDEA 902
>NP_003175
          Length = 1199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LDEAYV 8
           +DEAYV
Sbjct: 309 IDEAYV 314
>XP_005276824
          Length = 386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KILDEAYVM 9
           K  +EAYVM
Sbjct: 189 KSKEEAYVM 197
>XP_005276823
          Length = 386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KILDEAYVM 9
           K  +EAYVM
Sbjct: 189 KSKEEAYVM 197
>XP_005276822
          Length = 421

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KILDEAYVM 9
           K  +EAYVM
Sbjct: 224 KSKEEAYVM 232
>XP_006726278
          Length = 434

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KILDEAYVM 9
           K  +EAYVM
Sbjct: 237 KSKEEAYVM 245
>XP_005276821
          Length = 438

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KILDEAYVM 9
           K  +EAYVM
Sbjct: 241 KSKEEAYVM 249
>XP_006726277
          Length = 506

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KILDEAYVM 9
           K  +EAYVM
Sbjct: 309 KSKEEAYVM 317
>XP_005276820
          Length = 510

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KILDEAYVM 9
           K  +EAYVM
Sbjct: 313 KSKEEAYVM 321
>XP_005276819
          Length = 511

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KILDEAYVM 9
           K  +EAYVM
Sbjct: 314 KSKEEAYVM 322
>XP_005276818
          Length = 511

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KILDEAYVM 9
           K  +EAYVM
Sbjct: 314 KSKEEAYVM 322
>XP_005268078
          Length = 1272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   KILDEA 6
           KILDEA
Sbjct: 837 KILDEA 842
>XP_006716684
          Length = 1251

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LDEAYV 8
           +DEAYV
Sbjct: 309 IDEAYV 314
>XP_006716108
          Length = 451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KILDEAYV 8
           K+L EAY+
Sbjct: 176 KLLQEAYM 183
>XP_006716107
          Length = 579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KILDEAYV 8
           K+L EAY+
Sbjct: 379 KLLQEAYM 386
>XP_006716106
          Length = 654

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   KILDEAYV 8
           K+L EAY+
Sbjct: 379 KLLQEAYM 386
>XP_005249243
          Length = 651

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  LDEAYV 8
          +DEAYV
Sbjct: 52 IDEAYV 57
>XP_005248520
          Length = 386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KILDEAYVM 9
           K  +EAYVM
Sbjct: 189 KSKEEAYVM 197
>XP_005248519
          Length = 386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KILDEAYVM 9
           K  +EAYVM
Sbjct: 189 KSKEEAYVM 197
>XP_005248518
          Length = 421

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KILDEAYVM 9
           K  +EAYVM
Sbjct: 224 KSKEEAYVM 232
>XP_006714633
          Length = 434

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KILDEAYVM 9
           K  +EAYVM
Sbjct: 237 KSKEEAYVM 245
>XP_005248517
          Length = 438

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KILDEAYVM 9
           K  +EAYVM
Sbjct: 241 KSKEEAYVM 249
>XP_006714632
          Length = 506

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KILDEAYVM 9
           K  +EAYVM
Sbjct: 309 KSKEEAYVM 317
>XP_005248516
          Length = 510

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KILDEAYVM 9
           K  +EAYVM
Sbjct: 313 KSKEEAYVM 321
>XP_005248515
          Length = 511

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KILDEAYVM 9
           K  +EAYVM
Sbjct: 314 KSKEEAYVM 322
>XP_005248514
          Length = 511

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   KILDEAYVM 9
           K  +EAYVM
Sbjct: 314 KSKEEAYVM 322
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.141    0.368 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 560,226
Number of extensions: 1019
Number of successful extensions: 54
Number of sequences better than 10000.0: 54
Number of HSP's gapped: 54
Number of HSP's successfully gapped: 54
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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