Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004809                                                              16    5631
XP_006726657                                                           16    5631
XP_006725285                                                           16    5631
NP_060854                                                              15    9605
NP_064627                                                              15    9605
NP_001265166                                                           15    9605
NP_001186506                                                           15    9605
NP_055069                                                              15    9605
XP_006719258                                                           15    9605
XP_005268620                                                           15    9605
XP_005268619                                                           15    9605
XP_006713328                                                           15    9605
XP_006713327                                                           15    9605
XP_006713326                                                           15    9605
XP_006713325                                                           15    9605
XP_006713324                                                           15    9605
XP_005265385                                                           15    9605
>NP_004809
          Length = 820

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   KELLAVLE 8
           K+LLA+LE
Sbjct: 653 KKLLAILE 660
>XP_006726657
          Length = 633

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KELLAVLEM 9
           KE+L +LEM
Sbjct: 317 KEMLELLEM 325
>XP_006725285
          Length = 633

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   KELLAVLEM 9
           KE+L +LEM
Sbjct: 317 KEMLELLEM 325
>NP_060854
          Length = 307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ELLAVLE 8
           ELLAV+E
Sbjct: 202 ELLAVIE 208
>NP_064627
          Length = 1388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KELLAVLE 8
           KE+L VLE
Sbjct: 929 KEILKVLE 936
>NP_001265166
          Length = 183

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KELLAVLE 8
           KEL AVLE
Sbjct: 130 KELPAVLE 137
>NP_001186506
          Length = 511

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ELLAVLE 8
           ELLAV+E
Sbjct: 406 ELLAVIE 412
>NP_055069
          Length = 443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KELLAVLE 8
           KEL AVLE
Sbjct: 390 KELPAVLE 397
>XP_006719258
          Length = 183

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KELLAVLE 8
           KEL AVLE
Sbjct: 130 KELPAVLE 137
>XP_005268620
          Length = 340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KELLAVLE 8
           KEL AVLE
Sbjct: 287 KELPAVLE 294
>XP_005268619
          Length = 340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   KELLAVLE 8
           KEL AVLE
Sbjct: 287 KELPAVLE 294
>XP_006713328
          Length = 992

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KELLAVLE 8
           KE+L VLE
Sbjct: 929 KEILKVLE 936
>XP_006713327
          Length = 1023

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KELLAVLE 8
           KE+L VLE
Sbjct: 564 KEILKVLE 571
>XP_006713326
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KELLAVLE 8
           KE+L VLE
Sbjct: 929 KEILKVLE 936
>XP_006713325
          Length = 1195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KELLAVLE 8
           KE+L VLE
Sbjct: 929 KEILKVLE 936
>XP_006713324
          Length = 1285

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KELLAVLE 8
           KE+L VLE
Sbjct: 929 KEILKVLE 936
>XP_005265385
          Length = 1291

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   KELLAVLE 8
           KE+L VLE
Sbjct: 832 KEILKVLE 839
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.136    0.310 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 389,182
Number of extensions: 819
Number of successful extensions: 17
Number of sequences better than 10000.0: 17
Number of HSP's gapped: 17
Number of HSP's successfully gapped: 17
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package