Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              18    1482
NP_001263689                                                           18    1482
NP_001119584                                                           18    1482
NP_001119586                                                           18    1482
NP_001263625                                                           18    1482
NP_001119590                                                           18    1482
NP_001263690                                                           18    1482
NP_001119585                                                           18    1482
NP_001263624                                                           18    1482
NP_001119588                                                           18    1482
NP_001119587                                                           18    1482
NP_001119589                                                           18    1482
NP_001263627                                                           18    1482
NP_001263628                                                           18    1482
NP_001263626                                                           18    1482
NP_110394                                                              17    2528
XP_006717358                                                           17    2528
XP_005252305                                                           17    2528
XP_005252303                                                           17    2528
XP_006717357                                                           17    2528
XP_005252304                                                           17    2528
XP_005252302                                                           17    2528
XP_005252301                                                           17    2528
XP_005252300                                                           17    2528
NP_620411                                                              17    3301
XP_005271777                                                           17    3301
NP_001186028                                                           16    5631
NP_001186026                                                           16    5631
NP_001186027                                                           16    5631
NP_001186025                                                           16    5631
NP_073153                                                              16    5631
NP_003924                                                              16    5631
NP_001273393                                                           16    5631
XP_006712754                                                           16    5631
XP_006712753                                                           16    5631
NP_848927                                                              16    7355
NP_079065                                                              16    7355
NP_001138397                                                           16    7355
NP_001269849                                                           16    7355
NP_001171517                                                           16    7355
NP_002453                                                              16    7355
NP_057422                                                              16    7355
NP_002421                                                              16    7355
NP_001034485                                                           16    7355
NP_001193856                                                           16    7355
XP_005261039                                                           16    7355
XP_005261038                                                           16    7355
XP_005261037                                                           16    7355
XP_005261036                                                           16    7355
XP_005261035                                                           16    7355
XP_006724068                                                           16    7355
XP_005256334                                                           16    7355
XP_006718037                                                           16    7355
XP_006718036                                                           16    7355
XP_006718035                                                           16    7355
XP_006718034                                                           16    7355
XP_005251157                                                           16    7355
XP_005251156                                                           16    7355
XP_006715067                                                           16    7355
NP_001128251                                                           16    7355
NP_776161                                                              15    9605
XP_006714634                                                           15    9605
XP_005271976                                                           15    9605
>NP_000537
          Length = 393

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           ITLE SSGN
Sbjct: 255 ITLEDSSGN 263
>NP_001263689
          Length = 354

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           ITLE SSGN
Sbjct: 216 ITLEDSSGN 224
>NP_001119584
          Length = 393

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           ITLE SSGN
Sbjct: 255 ITLEDSSGN 263
>NP_001119586
          Length = 341

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           ITLE SSGN
Sbjct: 255 ITLEDSSGN 263
>NP_001263625
          Length = 302

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           ITLE SSGN
Sbjct: 216 ITLEDSSGN 224
>NP_001119590
          Length = 354

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           ITLE SSGN
Sbjct: 216 ITLEDSSGN 224
>NP_001263690
          Length = 354

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           ITLE SSGN
Sbjct: 216 ITLEDSSGN 224
>NP_001119585
          Length = 346

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           ITLE SSGN
Sbjct: 255 ITLEDSSGN 263
>NP_001263624
          Length = 307

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           ITLE SSGN
Sbjct: 216 ITLEDSSGN 224
>NP_001119588
          Length = 209

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           ITLE SSGN
Sbjct: 123 ITLEDSSGN 131
>NP_001119587
          Length = 261

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           ITLE SSGN
Sbjct: 123 ITLEDSSGN 131
>NP_001119589
          Length = 214

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           ITLE SSGN
Sbjct: 123 ITLEDSSGN 131
>NP_001263627
          Length = 182

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           ITLE SSGN
Sbjct: 96  ITLEDSSGN 104
>NP_001263628
          Length = 187

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           ITLE SSGN
Sbjct: 96  ITLEDSSGN 104
>NP_001263626
          Length = 234

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           ITLE SSGN
Sbjct: 96  ITLEDSSGN 104
>NP_110394
          Length = 1439

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           + +EVSSGN
Sbjct: 725 VNVEVSSGN 733
>XP_006717358
          Length = 831

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           + +EVSSGN
Sbjct: 725 VNVEVSSGN 733
>XP_005252305
          Length = 1407

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           + +EVSSGN
Sbjct: 725 VNVEVSSGN 733
>XP_005252303
          Length = 1439

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           + +EVSSGN
Sbjct: 725 VNVEVSSGN 733
>XP_006717357
          Length = 1439

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           + +EVSSGN
Sbjct: 725 VNVEVSSGN 733
>XP_005252304
          Length = 1439

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           + +EVSSGN
Sbjct: 725 VNVEVSSGN 733
>XP_005252302
          Length = 1439

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           + +EVSSGN
Sbjct: 725 VNVEVSSGN 733
>XP_005252301
          Length = 1439

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           + +EVSSGN
Sbjct: 725 VNVEVSSGN 733
>XP_005252300
          Length = 1439

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ITLEVSSGN 9
           + +EVSSGN
Sbjct: 725 VNVEVSSGN 733
>NP_620411
          Length = 390

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ITLEVSSG 8
           +TLEVS+G
Sbjct: 237 VTLEVSTG 244
>XP_005271777
          Length = 211

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  ITLEVSSG 8
          +TLEVS+G
Sbjct: 58 VTLEVSTG 65
>NP_001186028
          Length = 1124

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ITLEVSSG 8
           +TLEV+SG
Sbjct: 591 MTLEVASG 598
>NP_001186026
          Length = 1152

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ITLEVSSG 8
           +TLEV+SG
Sbjct: 619 MTLEVASG 626
>NP_001186027
          Length = 1129

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ITLEVSSG 8
           +TLEV+SG
Sbjct: 596 MTLEVASG 603
>NP_001186025
          Length = 1116

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ITLEVSSG 8
           +TLEV+SG
Sbjct: 583 MTLEVASG 590
>NP_073153
          Length = 1944

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ITLEVSSGN 9
           +TLE+S+G+
Sbjct: 595 VTLELSNGS 603
>NP_003924
          Length = 1187

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ITLEVSSG 8
           +TLEV+SG
Sbjct: 654 MTLEVASG 661
>NP_001273393
          Length = 1169

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ITLEVSSG 8
           +TLEV+SG
Sbjct: 636 MTLEVASG 643
>XP_006712754
          Length = 1784

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ITLEVSSGN 9
           +TLE+S+G+
Sbjct: 435 VTLELSNGS 443
>XP_006712753
          Length = 1846

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ITLEVSSGN 9
           +TLE+S+G+
Sbjct: 497 VTLELSNGS 505
>NP_848927
          Length = 582

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TLEVSSG 8
           TL+VSSG
Sbjct: 268 TLQVSSG 274
>NP_079065
          Length = 517

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITLEVSSG 8
           +TL VSSG
Sbjct: 197 VTLAVSSG 204
>NP_001138397
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ITLEVSS 7
           ITLE+SS
Sbjct: 162 ITLEISS 168
>NP_001269849
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ITLEVSS 7
           ITLE+SS
Sbjct: 162 ITLEISS 168
>NP_001171517
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ITLEVSS 7
           ITLE+SS
Sbjct: 162 ITLEISS 168
>NP_002453
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ITLEVSS 7
           ITLE+SS
Sbjct: 162 ITLEISS 168
>NP_057422
          Length = 975

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   EVSSGN 9
           EVSSGN
Sbjct: 195 EVSSGN 200
>NP_002421
          Length = 1320

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TLEVSSGN 9
           TLE +SGN
Sbjct: 923 TLESTSGN 930
>NP_001034485
          Length = 716

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TLEVSSG 8
           TLE+SSG
Sbjct: 164 TLELSSG 170
>NP_001193856
          Length = 4707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ITLEVSSG 8
            +TLEVS G
Sbjct: 1130 LTLEVSRG 1137
>XP_005261039
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ITLEVSS 7
           ITLE+SS
Sbjct: 162 ITLEISS 168
>XP_005261038
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ITLEVSS 7
           ITLE+SS
Sbjct: 162 ITLEISS 168
>XP_005261037
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ITLEVSS 7
           ITLE+SS
Sbjct: 162 ITLEISS 168
>XP_005261036
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ITLEVSS 7
           ITLE+SS
Sbjct: 162 ITLEISS 168
>XP_005261035
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ITLEVSS 7
           ITLE+SS
Sbjct: 162 ITLEISS 168
>XP_006724068
          Length = 685

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ITLEVSS 7
           ITLE+SS
Sbjct: 185 ITLEISS 191
>XP_005256334
          Length = 263

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1 ITLEVSSG 8
         +TLE+S+G
Sbjct: 1 MTLEISAG 8
>XP_006718037
          Length = 517

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITLEVSSG 8
           +TL VSSG
Sbjct: 197 VTLAVSSG 204
>XP_006718036
          Length = 517

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITLEVSSG 8
           +TL VSSG
Sbjct: 197 VTLAVSSG 204
>XP_006718035
          Length = 517

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITLEVSSG 8
           +TL VSSG
Sbjct: 197 VTLAVSSG 204
>XP_006718034
          Length = 517

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITLEVSSG 8
           +TL VSSG
Sbjct: 197 VTLAVSSG 204
>XP_005251157
          Length = 381

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TLEVSSG 8
           TL+VSSG
Sbjct: 268 TLQVSSG 274
>XP_005251156
          Length = 549

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TLEVSSG 8
           TL+VSSG
Sbjct: 268 TLQVSSG 274
>XP_006715067
          Length = 4707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    ITLEVSSG 8
            +TLEVS G
Sbjct: 1130 LTLEVSRG 1137
>NP_001128251
          Length = 1015

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   EVSSGN 9
           EVSSGN
Sbjct: 235 EVSSGN 240
>NP_776161
          Length = 990

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITLEVSSG 8
           ITL VS+G
Sbjct: 579 ITLNVSTG 586
>XP_006714634
          Length = 507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITLEVSSG 8
           ITL VS+G
Sbjct: 96  ITLNVSTG 103
>XP_005271976
          Length = 582

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ITLEVSSG 8
           ITL VS+G
Sbjct: 171 ITLNVSTG 178
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.298    0.120    0.288 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 465,738
Number of extensions: 778
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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