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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000360                                                              18    1135
XP_005268094                                                           18    1135
NP_057291                                                              17    3301
XP_005246225                                                           17    3301
XP_005246224                                                           17    3301
NP_852111                                                              17    4312
NP_000136                                                              17    4312
NP_001230396                                                           16    5631
NP_061834                                                              16    5631
NP_001001895                                                           16    5631
NP_065784                                                              16    7355
XP_005247723                                                           16    7355
NP_001116700                                                           16    7355
NP_114113                                                              15    9605
NP_061875                                                              15    9605
XP_005264434                                                           15    9605
XP_005264433                                                           15    9605
XP_005264432                                                           15    9605
XP_005264431                                                           15    9605

>NP_000360
          Length = 764

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ISSYAKVS 8
           ISSYAKVS
Sbjct: 560 ISSYAKVS 567



>XP_005268094
          Length = 764

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ISSYAKVS 8
           ISSYAKVS
Sbjct: 560 ISSYAKVS 567



>NP_057291
          Length = 684

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ISSYAKVSN 9
           +S Y KVSN
Sbjct: 107 LSDYVKVSN 115



>XP_005246225
          Length = 647

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ISSYAKVSN 9
          +S Y KVSN
Sbjct: 70 LSDYVKVSN 78



>XP_005246224
          Length = 674

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ISSYAKVSN 9
           +S Y KVSN
Sbjct: 97  LSDYVKVSN 105



>NP_852111
          Length = 669

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ISSYAKVS 8
           ISSY KVS
Sbjct: 482 ISSYMKVS 489



>NP_000136
          Length = 695

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ISSYAKVS 8
           ISSY KVS
Sbjct: 508 ISSYMKVS 515



>NP_001230396
          Length = 526

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  YAKVSN 9
          YAKVSN
Sbjct: 9  YAKVSN 14



>NP_061834
          Length = 661

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  YAKVSN 9
          YAKVSN
Sbjct: 9  YAKVSN 14



>NP_001001895
          Length = 623

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  YAKVSN 9
          YAKVSN
Sbjct: 9  YAKVSN 14



>NP_065784
          Length = 1381

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SSYAKVSN 9
           +SY K+SN
Sbjct: 585 TSYIKISN 592



>XP_005247723
          Length = 1481

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SSYAKVSN 9
           +SY K+SN
Sbjct: 685 TSYIKISN 692



>NP_001116700
          Length = 125

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  ISSYAKVSN 9
          IS YAKV +
Sbjct: 27 ISGYAKVGS 35



>NP_114113
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ISSYAKVSN 9
           IS Y KVS+
Sbjct: 541 ISKYLKVSS 549



>NP_061875
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ISSYAKVSN 9
           ++ Y+K+SN
Sbjct: 736 LTMYSKISN 744



>XP_005264434
          Length = 843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ISSYAKVSN 9
           ++ Y+K+SN
Sbjct: 653 LTMYSKISN 661



>XP_005264433
          Length = 899

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ISSYAKVSN 9
           ++ Y+K+SN
Sbjct: 709 LTMYSKISN 717



>XP_005264432
          Length = 899

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ISSYAKVSN 9
           ++ Y+K+SN
Sbjct: 709 LTMYSKISN 717



>XP_005264431
          Length = 928

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ISSYAKVSN 9
           ++ Y+K+SN
Sbjct: 738 LTMYSKISN 746



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.297    0.108    0.252 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 373,120
Number of extensions: 406
Number of successful extensions: 19
Number of sequences better than 10000.0: 19
Number of HSP's gapped: 19
Number of HSP's successfully gapped: 19
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)