Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              18    1482
NP_001263689                                                           18    1482
NP_001119584                                                           18    1482
NP_001119586                                                           18    1482
NP_001263625                                                           18    1482
NP_001119590                                                           18    1482
NP_001263690                                                           18    1482
NP_001119585                                                           18    1482
NP_001263624                                                           18    1482
NP_001119588                                                           18    1482
NP_001119587                                                           18    1482
NP_001119589                                                           18    1482
NP_001263627                                                           18    1482
NP_001263628                                                           18    1482
NP_001263626                                                           18    1482
NP_001159921                                                           16    5631
NP_000224                                                              16    5631
NP_002209                                                              16    5631
NP_000360                                                              16    5631
XP_005268094                                                           16    5631
XP_005264366                                                           16    5631
XP_006712078                                                           16    5631
NP_000737                                                              16    7355
NP_001177384                                                           16    7355
NP_683709                                                              16    7355
NP_647536                                                              16    7355
XP_005276529                                                           16    7355
XP_005254807                                                           16    7355
NP_001004740                                                           16    7355
NP_001004741                                                           16    7355
NP_001005487                                                           16    7355
NP_473445                                                              15    9605
NP_060132                                                              15    9605
NP_001005236                                                           15    9605
NP_062873                                                              15    9605
NP_001170781                                                           15    9605
NP_112145                                                              15    9605
NP_062874                                                              15    9605
XP_005275584                                                           15    9605
XP_005275585                                                           15    9605
XP_005275535                                                           15    9605
XP_006726054                                                           15    9605
XP_005275424                                                           15    9605
XP_006726053                                                           15    9605
XP_005275425                                                           15    9605
XP_005275363                                                           15    9605
XP_005275290                                                           15    9605
XP_005275291                                                           15    9605
XP_005275240                                                           15    9605
XP_006725873                                                           15    9605
XP_005275148                                                           15    9605
XP_006725872                                                           15    9605
XP_005275149                                                           15    9605
XP_005275105                                                           15    9605
XP_005274994                                                           15    9605
XP_005274995                                                           15    9605
XP_005272950                                                           15    9605
XP_005272848                                                           15    9605
XP_005272849                                                           15    9605
XP_005274949                                                           15    9605
XP_006725096                                                           15    9605
XP_005274902                                                           15    9605
XP_006725095                                                           15    9605
XP_005274903                                                           15    9605
XP_005249464                                                           15    9605
XP_005249065                                                           15    9605
XP_005249066                                                           15    9605
NP_001170782                                                           15    9605
NP_000863                                                              15    9605
NP_009091                                                              15    9605
NP_001004454                                                           15    9605
NP_703145                                                              15    9605
>NP_000537
          Length = 393

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ILTIITLE 8
           ILTIITLE
Sbjct: 251 ILTIITLE 258
>NP_001263689
          Length = 354

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ILTIITLE 8
           ILTIITLE
Sbjct: 212 ILTIITLE 219
>NP_001119584
          Length = 393

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ILTIITLE 8
           ILTIITLE
Sbjct: 251 ILTIITLE 258
>NP_001119586
          Length = 341

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ILTIITLE 8
           ILTIITLE
Sbjct: 251 ILTIITLE 258
>NP_001263625
          Length = 302

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ILTIITLE 8
           ILTIITLE
Sbjct: 212 ILTIITLE 219
>NP_001119590
          Length = 354

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ILTIITLE 8
           ILTIITLE
Sbjct: 212 ILTIITLE 219
>NP_001263690
          Length = 354

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ILTIITLE 8
           ILTIITLE
Sbjct: 212 ILTIITLE 219
>NP_001119585
          Length = 346

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ILTIITLE 8
           ILTIITLE
Sbjct: 251 ILTIITLE 258
>NP_001263624
          Length = 307

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ILTIITLE 8
           ILTIITLE
Sbjct: 212 ILTIITLE 219
>NP_001119588
          Length = 209

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ILTIITLE 8
           ILTIITLE
Sbjct: 119 ILTIITLE 126
>NP_001119587
          Length = 261

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ILTIITLE 8
           ILTIITLE
Sbjct: 119 ILTIITLE 126
>NP_001119589
          Length = 214

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ILTIITLE 8
           ILTIITLE
Sbjct: 119 ILTIITLE 126
>NP_001263627
          Length = 182

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  ILTIITLE 8
          ILTIITLE
Sbjct: 92 ILTIITLE 99
>NP_001263628
          Length = 187

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  ILTIITLE 8
          ILTIITLE
Sbjct: 92 ILTIITLE 99
>NP_001263626
          Length = 234

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  ILTIITLE 8
          ILTIITLE
Sbjct: 92 ILTIITLE 99
>NP_001159921
          Length = 900

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ILTIITLEY 9
           +LT +T EY
Sbjct: 461 LLTAVTFEY 469
>NP_000224
          Length = 699

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LTIITLE 8
           LT+ITLE
Sbjct: 457 LTVITLE 463
>NP_002209
          Length = 930

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ILTIITLEY 9
           +LT +T EY
Sbjct: 461 LLTAVTFEY 469
>NP_000360
          Length = 764

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LTIITLE 8
           LT+ITLE
Sbjct: 512 LTVITLE 518
>XP_005268094
          Length = 764

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LTIITLE 8
           LT+ITLE
Sbjct: 512 LTVITLE 518
>XP_005264366
          Length = 380

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LTIITLE 8
           LT+ITLE
Sbjct: 138 LTVITLE 144
>XP_006712078
          Length = 389

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LTIITLE 8
           LT+ITLE
Sbjct: 147 LTVITLE 153
>NP_000737
          Length = 502

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ILTIITLEY 9
           ++T+I L+Y
Sbjct: 309 VVTVIVLQY 317
>NP_001177384
          Length = 531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ILTIITLEY 9
           ++T+I L+Y
Sbjct: 338 VVTVIVLQY 346
>NP_683709
          Length = 321

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ILTIITLEY 9
           ++T+I L+Y
Sbjct: 128 VVTVIVLQY 136
>NP_647536
          Length = 412

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ILTIITLEY 9
           ++T+I L+Y
Sbjct: 219 VVTVIVLQY 227
>XP_005276529
          Length = 412

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ILTIITLEY 9
           ++T+I L+Y
Sbjct: 219 VVTVIVLQY 227
>XP_005254807
          Length = 321

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ILTIITLEY 9
           ++T+I L+Y
Sbjct: 128 VVTVIVLQY 136
>NP_001004740
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LTI+TL Y
Sbjct: 245 LTIVTLFY 252
>NP_001004741
          Length = 315

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LTI+TL Y
Sbjct: 245 LTIVTLFY 252
>NP_001005487
          Length = 307

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 242 LTVVTLYY 249
>NP_473445
          Length = 311

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LTIITLEY 9
          LTIITL +
Sbjct: 40 LTIITLTF 47
>NP_060132
          Length = 2022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TIITLEY 9
           TI+TLE+
Sbjct: 756 TILTLEF 762
>NP_001005236
          Length = 310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 245 LTVVTLFY 252
>NP_062873
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  ILTIITL 7
          ILT+ITL
Sbjct: 87 ILTLITL 93
>NP_001170781
          Length = 2017

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TIITLEY 9
           TI+TLE+
Sbjct: 751 TILTLEF 757
>NP_112145
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>NP_062874
          Length = 432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  ILTIITL 7
          ILT+ITL
Sbjct: 87 ILTLITL 93
>XP_005275584
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_005275585
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_005275535
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_006726054
          Length = 238

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 165 LTVVTLFY 172
>XP_005275424
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_006726053
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_005275425
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_005275363
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_005275290
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_005275291
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_005275240
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_006725873
          Length = 238

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 165 LTVVTLFY 172
>XP_005275148
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_006725872
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_005275149
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_005275105
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_005274994
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_005274995
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_005272950
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_005272848
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_005272849
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_005274949
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_006725096
          Length = 238

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 165 LTVVTLFY 172
>XP_005274902
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_006725095
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_005274903
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_005249464
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_005249065
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>XP_005249066
          Length = 316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>NP_001170782
          Length = 2017

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TIITLEY 9
           TI+TLE+
Sbjct: 751 TILTLEF 757
>NP_000863
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  ILTIITL 7
          ILT+ITL
Sbjct: 87 ILTLITL 93
>NP_009091
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 243 LTVVTLFY 250
>NP_001004454
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 246 LTVVTLFY 253
>NP_703145
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LTIITLEY 9
           LT++TL Y
Sbjct: 241 LTVVTLFY 248
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.334    0.155    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 425,823
Number of extensions: 751
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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