Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005350                                                              19     665
NP_055524                                                              17    2528
NP_005893                                                              17    3301
NP_005891                                                              17    3301
NP_001003688                                                           17    3301
NP_001003652                                                           17    3301
NP_001138576                                                           17    3301
NP_001129409                                                           17    3301
NP_001138574                                                           17    3301
NP_005892                                                              17    3301
NP_001138575                                                           17    3301
NP_001001419                                                           17    3301
NP_005894                                                              17    3301
NP_001001420                                                           17    3301
NP_536722                                                              17    3301
NP_005896                                                              17    3301
NP_001120689                                                           17    3301
XP_005266835                                                           17    3301
XP_006722514                                                           17    3301
XP_005258316                                                           17    3301
XP_006720569                                                           17    3301
XP_005263050                                                           17    3301
XP_005263049                                                           17    3301
XP_005263048                                                           17    3301
XP_006714280                                                           17    3301
NP_001025034                                                           17    3301
NP_065820                                                              17    4312
NP_001238965                                                           16    7355
NP_001238966                                                           16    7355
NP_002859                                                              16    7355
NP_004574                                                              16    7355
NP_958842                                                              16    7355
NP_001238968                                                           16    7355
XP_005269108                                                           16    7355
XP_005269109                                                           16    7355
XP_006719603                                                           16    7355
NP_660156                                                              16    7355
NP_060064                                                              16    7355
NP_004153                                                              16    7355
NP_055223                                                              15    9605
NP_005662                                                              15    9605
NP_001269128                                                           15    9605
NP_001269118                                                           15    9605
NP_004715                                                              15    9605
NP_001257826                                                           15    9605
NP_001257825                                                           15    9605
NP_001257823                                                           15    9605
NP_001257824                                                           15    9605
NP_065073                                                              15    9605
XP_005274723                                                           15    9605
XP_006719006                                                           15    9605
XP_006715582                                                           15    9605
NP_001005487                                                           15    9605
>NP_005350
          Length = 552

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ILRMRFVKG 9
           ILRM FVKG
Sbjct: 500 ILRMSFVKG 508
>NP_055524
          Length = 3546

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LRMRFVKG 9
           +RMRF++G
Sbjct: 899 IRMRFIEG 906
>NP_005893
          Length = 425

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRMRFVKG 9
           +RM FVKG
Sbjct: 372 IRMSFVKG 379
>NP_005891
          Length = 465

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRMRFVKG 9
           +RM FVKG
Sbjct: 412 IRMSFVKG 419
>NP_001003688
          Length = 465

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRMRFVKG 9
           +RM FVKG
Sbjct: 412 IRMSFVKG 419
>NP_001003652
          Length = 467

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRMRFVKG 9
           +RM FVKG
Sbjct: 414 IRMSFVKG 421
>NP_001138576
          Length = 230

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRMRFVKG 9
           +RM FVKG
Sbjct: 177 IRMSFVKG 184
>NP_001129409
          Length = 437

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRMRFVKG 9
           +RM FVKG
Sbjct: 384 IRMSFVKG 391
>NP_001138574
          Length = 320

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRMRFVKG 9
           +RM FVKG
Sbjct: 267 IRMSFVKG 274
>NP_005892
          Length = 467

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRMRFVKG 9
           +RM FVKG
Sbjct: 414 IRMSFVKG 421
>NP_001138575
          Length = 381

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRMRFVKG 9
           +RM FVKG
Sbjct: 328 IRMSFVKG 335
>NP_001001419
          Length = 465

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRMRFVKG 9
           +RM FVKG
Sbjct: 412 IRMSFVKG 419
>NP_005894
          Length = 465

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRMRFVKG 9
           +RM FVKG
Sbjct: 412 IRMSFVKG 419
>NP_001001420
          Length = 465

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRMRFVKG 9
           +RM FVKG
Sbjct: 412 IRMSFVKG 419
>NP_536722
          Length = 405

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ILRMRFVKG 9
           IL MR+ KG
Sbjct: 242 ILEMRYTKG 250
>NP_005896
          Length = 430

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRMRFVKG 9
           +RM FVKG
Sbjct: 377 IRMSFVKG 384
>NP_001120689
          Length = 467

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRMRFVKG 9
           +RM FVKG
Sbjct: 414 IRMSFVKG 421
>XP_005266835
          Length = 425

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ILRMRFVKG 9
           IL MR+ KG
Sbjct: 262 ILEMRYTKG 270
>XP_006722514
          Length = 467

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRMRFVKG 9
           +RM FVKG
Sbjct: 414 IRMSFVKG 421
>XP_005258316
          Length = 467

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRMRFVKG 9
           +RM FVKG
Sbjct: 414 IRMSFVKG 421
>XP_006720569
          Length = 373

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRMRFVKG 9
           +RM FVKG
Sbjct: 320 IRMSFVKG 327
>XP_005263050
          Length = 426

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRMRFVKG 9
           +RM FVKG
Sbjct: 373 IRMSFVKG 380
>XP_005263049
          Length = 465

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRMRFVKG 9
           +RM FVKG
Sbjct: 412 IRMSFVKG 419
>XP_005263048
          Length = 465

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRMRFVKG 9
           +RM FVKG
Sbjct: 412 IRMSFVKG 419
>XP_006714280
          Length = 465

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LRMRFVKG 9
           +RM FVKG
Sbjct: 412 IRMSFVKG 419
>NP_001025034
          Length = 191

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ILRMRFVKG 9
          +LRMR +KG
Sbjct: 66 VLRMRSLKG 74
>NP_065820
          Length = 1388

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    ILRMRFVKG 9
            ILR RF++G
Sbjct: 1269 ILRTRFLEG 1277
>NP_001238965
          Length = 215

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LRMRFVKG 9
          L +RFVKG
Sbjct: 36 LVLRFVKG 43
>NP_001238966
          Length = 174

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LRMRFVKG 9
          L +RFVKG
Sbjct: 36 LVLRFVKG 43
>NP_002859
          Length = 215

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LRMRFVKG 9
          L +RFVKG
Sbjct: 36 LVLRFVKG 43
>NP_004574
          Length = 216

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LRMRFVKG 9
          L +RFVKG
Sbjct: 37 LVLRFVKG 44
>NP_958842
          Length = 216

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LRMRFVKG 9
          L +RFVKG
Sbjct: 37 LVLRFVKG 44
>NP_001238968
          Length = 249

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LRMRFVKG 9
          L +RFVKG
Sbjct: 70 LVLRFVKG 77
>XP_005269108
          Length = 215

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LRMRFVKG 9
          L +RFVKG
Sbjct: 36 LVLRFVKG 43
>XP_005269109
          Length = 215

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LRMRFVKG 9
          L +RFVKG
Sbjct: 36 LVLRFVKG 43
>XP_006719603
          Length = 250

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LRMRFVKG 9
          L +RFVKG
Sbjct: 71 LVLRFVKG 78
>NP_660156
          Length = 198

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LRMRFVKG 9
          L +RFVKG
Sbjct: 23 LVLRFVKG 30
>NP_060064
          Length = 199

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LRMRFVKG 9
          L +RFVKG
Sbjct: 23 LVLRFVKG 30
>NP_004153
          Length = 215

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LRMRFVKG 9
          L +RFVKG
Sbjct: 36 LVLRFVKG 43
>NP_055223
          Length = 180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   LRMRFVK 8
           +RMRF++
Sbjct: 163 IRMRFIR 169
>NP_005662
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILRMRFVK 8
           +LR RF+K
Sbjct: 203 VLRRRFLK 210
>NP_001269128
          Length = 229

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILRMRFVK 8
           +LR RF+K
Sbjct: 162 VLRRRFLK 169
>NP_001269118
          Length = 233

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILRMRFVK 8
           +LR RF+K
Sbjct: 166 VLRRRFLK 173
>NP_004715
          Length = 779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   MRFVKG 9
           MRF+KG
Sbjct: 378 MRFLKG 383
>NP_001257826
          Length = 114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   LRMRFVK 8
           +RMRF++
Sbjct: 97  IRMRFIR 103
>NP_001257825
          Length = 134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   LRMRFVK 8
           +RMRF++
Sbjct: 117 IRMRFIR 123
>NP_001257823
          Length = 188

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   LRMRFVK 8
           +RMRF++
Sbjct: 171 IRMRFIR 177
>NP_001257824
          Length = 134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   LRMRFVK 8
           +RMRF++
Sbjct: 117 IRMRFIR 123
>NP_065073
          Length = 2177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    MRFVKG 9
            M+FVKG
Sbjct: 1359 MKFVKG 1364
>XP_005274723
          Length = 220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  ILRMRFVKG 9
          I+R+R  KG
Sbjct: 16 IIRIRMAKG 24
>XP_006719006
          Length = 715

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   MRFVKG 9
           MRF+KG
Sbjct: 314 MRFLKG 319
>XP_006715582
          Length = 2106

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    MRFVKG 9
            M+FVKG
Sbjct: 1288 MKFVKG 1293
>NP_001005487
          Length = 307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILRMRFVKG 9
           ILR+R V+G
Sbjct: 222 ILRIRTVEG 230
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.352    0.164    0.472 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 370,582
Number of extensions: 625
Number of successful extensions: 53
Number of sequences better than 10000.0: 53
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.8 bits)
S2: 28 (15.4 bits)

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