Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              20     390
XP_006718908                                                           20     390
XP_005271621                                                           20     390
XP_006718907                                                           20     390
XP_006718906                                                           20     390
XP_005271619                                                           20     390
XP_005271618                                                           20     390
NP_005432                                                              16    5631
NP_653307                                                              16    5631
XP_005271175                                                           16    5631
NP_149044                                                              16    5631
NP_001124482                                                           16    7355
NP_061198                                                              16    7355
NP_002962                                                              16    7355
NP_001182399                                                           16    7355
XP_006720670                                                           16    7355
XP_005273744                                                           16    7355
XP_006713344                                                           16    7355
XP_006713343                                                           16    7355
NP_689485                                                              16    7355
NP_004940                                                              15    9605
NP_077740                                                              15    9605
NP_005742                                                              15    9605
NP_671714                                                              15    9605
NP_055826                                                              15    9605
NP_001185879                                                           15    9605
NP_689914                                                              15    9605
NP_055178                                                              15    9605
NP_001264984                                                           15    9605
NP_001274742                                                           15    9605
NP_001034806                                                           15    9605
NP_001010862                                                           15    9605
NP_001274743                                                           15    9605
NP_061840                                                              15    9605
XP_006724641                                                           15    9605
XP_006724640                                                           15    9605
XP_005258263                                                           15    9605
XP_006722279                                                           15    9605
XP_006722278                                                           15    9605
XP_005257947                                                           15    9605
XP_005257945                                                           15    9605
XP_006722277                                                           15    9605
XP_005266395                                                           15    9605
XP_006716519                                                           15    9605
XP_006715890                                                           15    9605
XP_005250160                                                           15    9605
XP_005250159                                                           15    9605
XP_005263298                                                           15    9605
XP_006714387                                                           15    9605
XP_006714386                                                           15    9605
XP_005263300                                                           15    9605
XP_006714385                                                           15    9605
XP_005263299                                                           15    9605
XP_006714384                                                           15    9605
XP_005263295                                                           15    9605
XP_006714383                                                           15    9605
XP_006714382                                                           15    9605
XP_006714381                                                           15    9605
NP_073623                                                              15    9605
>NP_000042
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ILLQDTNQS 9
            ILLQDTN+S
Sbjct: 1849 ILLQDTNES 1857
>XP_006718908
          Length = 1708

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ILLQDTNQS 9
           ILLQDTN+S
Sbjct: 501 ILLQDTNES 509
>XP_005271621
          Length = 2708

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ILLQDTNQS 9
            ILLQDTN+S
Sbjct: 1501 ILLQDTNES 1509
>XP_006718907
          Length = 3050

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ILLQDTNQS 9
            ILLQDTN+S
Sbjct: 1843 ILLQDTNES 1851
>XP_006718906
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ILLQDTNQS 9
            ILLQDTN+S
Sbjct: 1849 ILLQDTNES 1857
>XP_005271619
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ILLQDTNQS 9
            ILLQDTN+S
Sbjct: 1849 ILLQDTNES 1857
>XP_005271618
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ILLQDTNQS 9
            ILLQDTN+S
Sbjct: 1849 ILLQDTNES 1857
>NP_005432
          Length = 559

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ILLQDTNQS 9
           +LL DT QS
Sbjct: 327 VLLYDTQQS 335
>NP_653307
          Length = 125

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ILLQDTNQ 8
          I L+DTNQ
Sbjct: 81 IRLEDTNQ 88
>XP_005271175
          Length = 468

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LLQDTN 7
           LLQDTN
Sbjct: 462 LLQDTN 467
>NP_149044
          Length = 490

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LLQDTN 7
           LLQDTN
Sbjct: 484 LLQDTN 489
>NP_001124482
          Length = 763

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLQDTNQS 9
           LL+D NQS
Sbjct: 196 LLKDMNQS 203
>NP_061198
          Length = 1742

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LLQDTNQ 8
           L+QD+NQ
Sbjct: 724 LIQDSNQ 730
>NP_002962
          Length = 763

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLQDTNQS 9
           LL+D NQS
Sbjct: 196 LLKDMNQS 203
>NP_001182399
          Length = 795

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLQDTNQS 9
           LL+D NQS
Sbjct: 196 LLKDMNQS 203
>XP_006720670
          Length = 1712

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LLQDTNQ 8
           L+QD+NQ
Sbjct: 724 LIQDSNQ 730
>XP_005273744
          Length = 343

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILLQDTNQ 8
           ILLQDT +
Sbjct: 276 ILLQDTTK 283
>XP_006713344
          Length = 689

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLQDTNQS 9
           LL+D NQS
Sbjct: 196 LLKDMNQS 203
>XP_006713343
          Length = 763

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLQDTNQS 9
           LL+D NQS
Sbjct: 196 LLKDMNQS 203
>NP_689485
          Length = 453

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILLQDTNQ 8
           ILLQDT +
Sbjct: 386 ILLQDTTK 393
>NP_004940
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ILLQDTNQS 9
           I+LQD N +
Sbjct: 565 IILQDVNDN 573
>NP_077740
          Length = 901

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ILLQDTNQS 9
           I+LQD N +
Sbjct: 565 IILQDVNDN 573
>NP_005742
          Length = 3907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ILLQDTN 7
           I LQDTN
Sbjct: 500 IKLQDTN 506
>NP_671714
          Length = 3899

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ILLQDTN 7
           I LQDTN
Sbjct: 500 IKLQDTN 506
>NP_055826
          Length = 1858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   ILLQDTN 7
           +LLQD N
Sbjct: 152 VLLQDVN 158
>NP_001185879
          Length = 1880

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   ILLQDTN 7
           +LLQD N
Sbjct: 174 VLLQDVN 180
>NP_689914
          Length = 5058

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    ILLQDTNQ 8
            +LLQD+N+
Sbjct: 4157 MLLQDSNK 4164
>NP_055178
          Length = 4579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    ILLQDTN 7
            ILL DTN
Sbjct: 2451 ILLPDTN 2457
>NP_001264984
          Length = 4432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    ILLQDTN 7
            ILL DTN
Sbjct: 2304 ILLPDTN 2310
>NP_001274742
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  LLQDTNQ 8
          LLQD NQ
Sbjct: 16 LLQDGNQ 22
>NP_001034806
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLQDTNQ 8
           +LLQDT++
Sbjct: 295 LLLQDTSK 302
>NP_001010862
          Length = 258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LLQDTNQS 9
           +LQD+N S
Sbjct: 188 ILQDSNDS 195
>NP_001274743
          Length = 480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  LLQDTNQ 8
          LLQD NQ
Sbjct: 16 LLQDGNQ 22
>NP_061840
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  LLQDTNQ 8
          LLQD NQ
Sbjct: 16 LLQDGNQ 22
>XP_006724641
          Length = 258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LLQDTNQS 9
           +LQD+N S
Sbjct: 188 ILQDSNDS 195
>XP_006724640
          Length = 258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LLQDTNQS 9
           +LQD+N S
Sbjct: 188 ILQDSNDS 195
>XP_005258263
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ILLQDTNQS 9
           I+LQD N +
Sbjct: 422 IILQDVNDN 430
>XP_006722279
          Length = 1578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  ILLQDT 6
          ILLQDT
Sbjct: 94 ILLQDT 99
>XP_006722278
          Length = 1735

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ILLQDT 6
           ILLQDT
Sbjct: 251 ILLQDT 256
>XP_005257947
          Length = 1935

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ILLQDT 6
           ILLQDT
Sbjct: 486 ILLQDT 491
>XP_005257945
          Length = 1969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ILLQDT 6
           ILLQDT
Sbjct: 486 ILLQDT 491
>XP_006722277
          Length = 1970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ILLQDT 6
           ILLQDT
Sbjct: 486 ILLQDT 491
>XP_005266395
          Length = 4588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    ILLQDTN 7
            ILL DTN
Sbjct: 2460 ILLPDTN 2466
>XP_006716519
          Length = 346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  LLQDTNQ 8
          LLQD NQ
Sbjct: 16 LLQDGNQ 22
>XP_006715890
          Length = 3860

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ILLQDTN 7
           I LQDTN
Sbjct: 500 IKLQDTN 506
>XP_005250160
          Length = 3939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ILLQDTN 7
           I LQDTN
Sbjct: 500 IKLQDTN 506
>XP_005250159
          Length = 3952

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ILLQDTN 7
           I LQDTN
Sbjct: 500 IKLQDTN 506
>XP_005263298
          Length = 448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLQDTNQ 8
           +LLQDT++
Sbjct: 329 LLLQDTSK 336
>XP_006714387
          Length = 295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLQDTNQ 8
           +LLQDT++
Sbjct: 160 LLLQDTSK 167
>XP_006714386
          Length = 295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLQDTNQ 8
           +LLQDT++
Sbjct: 160 LLLQDTSK 167
>XP_005263300
          Length = 321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLQDTNQ 8
           +LLQDT++
Sbjct: 202 LLLQDTSK 209
>XP_006714385
          Length = 337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLQDTNQ 8
           +LLQDT++
Sbjct: 202 LLLQDTSK 209
>XP_005263299
          Length = 337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLQDTNQ 8
           +LLQDT++
Sbjct: 202 LLLQDTSK 209
>XP_006714384
          Length = 463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLQDTNQ 8
           +LLQDT++
Sbjct: 344 LLLQDTSK 351
>XP_005263295
          Length = 464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLQDTNQ 8
           +LLQDT++
Sbjct: 329 LLLQDTSK 336
>XP_006714383
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLQDTNQ 8
           +LLQDT++
Sbjct: 344 LLLQDTSK 351
>XP_006714382
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLQDTNQ 8
           +LLQDT++
Sbjct: 344 LLLQDTSK 351
>XP_006714381
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLQDTNQ 8
           +LLQDT++
Sbjct: 344 LLLQDTSK 351
>NP_073623
          Length = 271

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LQDTNQS 9
           LQD+NQ+
Sbjct: 119 LQDSNQN 125
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.309    0.125    0.304 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 595,463
Number of extensions: 1098
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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