Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              20     509
XP_005265800                                                           20     509
XP_006714103                                                           20     509
XP_006714102                                                           20     509
NP_001155238                                                           17    3301
NP_000678                                                              17    3301
XP_005260374                                                           17    3301
XP_005260373                                                           17    3301
NP_001014809                                                           17    4312
NP_001275591                                                           17    4312
NP_001304                                                              17    4312
NP_001275590                                                           17    4312
NP_001377                                                              17    4312
NP_001184222                                                           17    4312
NP_001231533                                                           17    4312
NP_001123380                                                           17    4312
XP_005248000                                                           17    4312
XP_005247999                                                           17    4312
XP_005247998                                                           17    4312
XP_005247997                                                           17    4312
NP_776176                                                              16    5631
NP_001177131                                                           16    5631
XP_005255954                                                           16    5631
XP_006721241                                                           16    5631
XP_005255953                                                           16    5631
NP_001177130                                                           16    5631
XP_006717822                                                           16    7355
XP_006717821                                                           16    7355
XP_005269749                                                           16    7355
XP_006717820                                                           16    7355
NP_065081                                                              16    7355
NP_001276976                                                           15    9605
NP_001276975                                                           15    9605
NP_001229602                                                           15    9605
NP_056143                                                              15    9605
NP_006612                                                              15    9605
NP_001229604                                                           15    9605
NP_001229603                                                           15    9605
NP_001229605                                                           15    9605
NP_001124194                                                           15    9605
NP_067646                                                              15    9605
NP_001124192                                                           15    9605
NP_001124195                                                           15    9605
XP_006724141                                                           15    9605
XP_005250294                                                           15    9605
XP_006711542                                                           15    9605
XP_006711541                                                           15    9605
XP_005245460                                                           15    9605
>NP_006197
          Length = 1089

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           +LLAQGKIV
Sbjct: 824 VLLAQGKIV 832
>XP_005265800
          Length = 1089

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           +LLAQGKIV
Sbjct: 824 VLLAQGKIV 832
>XP_006714103
          Length = 1111

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           +LLAQGKIV
Sbjct: 846 VLLAQGKIV 854
>XP_006714102
          Length = 1114

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           +LLAQGKIV
Sbjct: 849 VLLAQGKIV 857
>NP_001155238
          Length = 404

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           ILLA+G++V
Sbjct: 309 ILLAEGRLV 317
>NP_000678
          Length = 432

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           ILLA+G++V
Sbjct: 337 ILLAEGRLV 345
>XP_005260374
          Length = 404

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           ILLA+G++V
Sbjct: 309 ILLAEGRLV 317
>XP_005260373
          Length = 404

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           ILLA+G++V
Sbjct: 309 ILLAEGRLV 317
>NP_001014809
          Length = 686

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           ++++QGKIV
Sbjct: 559 VVISQGKIV 567
>NP_001275591
          Length = 566

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           ++++QGKIV
Sbjct: 439 VVISQGKIV 447
>NP_001304
          Length = 572

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           ++++QGKIV
Sbjct: 445 VVISQGKIV 453
>NP_001275590
          Length = 570

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           ++++QGKIV
Sbjct: 443 VVISQGKIV 451
>NP_001377
          Length = 572

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           ++++QGKIV
Sbjct: 445 VVISQGKIV 453
>NP_001184222
          Length = 677

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           ++++QGKIV
Sbjct: 550 VVISQGKIV 558
>NP_001231533
          Length = 536

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           ++++QGKIV
Sbjct: 409 VVISQGKIV 417
>NP_001123380
          Length = 575

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLAQGKIV 9
           LLAQG++V
Sbjct: 271 LLAQGEVV 278
>XP_005248000
          Length = 597

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           ++++QGKIV
Sbjct: 443 VVISQGKIV 451
>XP_005247999
          Length = 599

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           ++++QGKIV
Sbjct: 445 VVISQGKIV 453
>XP_005247998
          Length = 689

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           ++++QGKIV
Sbjct: 559 VVISQGKIV 567
>XP_005247997
          Length = 713

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           ++++QGKIV
Sbjct: 559 VVISQGKIV 567
>NP_776176
          Length = 468

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILLAQGKI 8
           +LL QGK+
Sbjct: 333 VLLTQGKV 340
>NP_001177131
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILLAQGKI 8
           +LL QGK+
Sbjct: 239 VLLTQGKV 246
>XP_005255954
          Length = 367

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILLAQGKI 8
           +LL QGK+
Sbjct: 139 VLLTQGKV 146
>XP_006721241
          Length = 372

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILLAQGKI 8
           +LL QGK+
Sbjct: 139 VLLTQGKV 146
>XP_005255953
          Length = 584

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILLAQGKI 8
           +LL QGK+
Sbjct: 356 VLLTQGKV 363
>NP_001177130
          Length = 463

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILLAQGKI 8
           +LL QGK+
Sbjct: 235 VLLTQGKV 242
>XP_006717822
          Length = 810

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILLAQGKI 8
           +LL QGK+
Sbjct: 672 VLLLQGKV 679
>XP_006717821
          Length = 846

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILLAQGKI 8
           +LL QGK+
Sbjct: 672 VLLLQGKV 679
>XP_005269749
          Length = 901

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILLAQGKI 8
           +LL QGK+
Sbjct: 672 VLLLQGKV 679
>XP_006717820
          Length = 949

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILLAQGKI 8
           +LL QGK+
Sbjct: 672 VLLLQGKV 679
>NP_065081
          Length = 951

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ILLAQGKI 8
           +LL QGK+
Sbjct: 672 VLLLQGKV 679
>NP_001276976
          Length = 1464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LLAQGK 7
           LLAQGK
Sbjct: 384 LLAQGK 389
>NP_001276975
          Length = 1300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LLAQGK 7
           LLAQGK
Sbjct: 221 LLAQGK 226
>NP_001229602
          Length = 483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           +LLA+G+++
Sbjct: 388 VLLAEGRLL 396
>NP_056143
          Length = 611

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           +LLA+G+++
Sbjct: 516 VLLAEGRLL 524
>NP_006612
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           +LLA+G+++
Sbjct: 435 VLLAEGRLL 443
>NP_001229604
          Length = 483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           +LLA+G+++
Sbjct: 388 VLLAEGRLL 396
>NP_001229603
          Length = 483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           +LLA+G+++
Sbjct: 388 VLLAEGRLL 396
>NP_001229605
          Length = 483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           +LLA+G+++
Sbjct: 388 VLLAEGRLL 396
>NP_001124194
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           +LLA+G+++
Sbjct: 413 VLLAEGRLL 421
>NP_067646
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLAQGKI 8
           ILL+QG++
Sbjct: 172 ILLSQGEV 179
>NP_001124192
          Length = 610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           +LLA+G+++
Sbjct: 515 VLLAEGRLL 523
>NP_001124195
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           +LLA+G+++
Sbjct: 413 VLLAEGRLL 421
>XP_006724141
          Length = 1426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LLAQGK 7
           LLAQGK
Sbjct: 346 LLAQGK 351
>XP_005250294
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ILLAQGKIV 9
           +LLA+G+++
Sbjct: 414 VLLAEGRLL 422
>XP_006711542
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLAQGKI 8
           ILL+QG++
Sbjct: 210 ILLSQGEV 217
>XP_006711541
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLAQGKI 8
           ILL+QG++
Sbjct: 210 ILLSQGEV 217
>XP_005245460
          Length = 606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ILLAQGKI 8
           ILL+QG++
Sbjct: 210 ILLSQGEV 217
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.333    0.153    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 432,723
Number of extensions: 463
Number of successful extensions: 48
Number of sequences better than 10000.0: 48
Number of HSP's gapped: 48
Number of HSP's successfully gapped: 48
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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