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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000236                                                              18    1482
NP_001120972                                                           18    1482
XP_006716052                                                           18    1482
XP_006716051                                                           18    1482
NP_115618                                                              17    4312
XP_006713726                                                           17    4312
NP_001265618                                                           16    5631
XP_005264801                                                           16    5631
XP_006713174                                                           16    5631
XP_005264800                                                           16    5631
NP_061891                                                              16    7355
XP_006714032                                                           16    7355
NP_054733                                                              15    9605
NP_000247                                                              15    9605
NP_003310                                                              15    9605
NP_597676                                                              15    9605
NP_001243779                                                           15    9605
NP_001252542                                                           15    9605
NP_596869                                                              15    9605
NP_001010985                                                           15    9605
XP_005260859                                                           15    9605
XP_005260858                                                           15    9605
XP_005260857                                                           15    9605
XP_006723671                                                           15    9605
XP_006723670                                                           15    9605
XP_005260854                                                           15    9605
XP_006723669                                                           15    9605
XP_006718301                                                           15    9605
XP_005246888                                                           15    9605
XP_006712788                                                           15    9605
XP_006712787                                                           15    9605
XP_006712786                                                           15    9605
XP_006710676                                                           15    9605
NP_071927                                                              15    9605
NP_001254479                                                           15    9605
NP_597681                                                              15    9605

>NP_000236
          Length = 1390

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ILFRVFAQS 9
           ILF VFAQS
Sbjct: 341 ILFGVFAQS 349



>NP_001120972
          Length = 1408

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ILFRVFAQS 9
           ILF VFAQS
Sbjct: 341 ILFGVFAQS 349



>XP_006716052
          Length = 1409

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ILFRVFAQS 9
           ILF VFAQS
Sbjct: 360 ILFGVFAQS 368



>XP_006716051
          Length = 1427

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ILFRVFAQS 9
           ILF VFAQS
Sbjct: 360 ILFGVFAQS 368



>NP_115618
          Length = 1896

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILFRVFAQ 8
           +LF VFAQ
Sbjct: 336 VLFTVFAQ 343



>XP_006713726
          Length = 1910

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILFRVFAQ 8
           +LF VFAQ
Sbjct: 354 VLFTVFAQ 361



>NP_001265618
          Length = 527

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LFRVFAQ 8
           LFR FAQ
Sbjct: 341 LFRAFAQ 347



>XP_005264801
          Length = 527

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LFRVFAQ 8
           LFR FAQ
Sbjct: 341 LFRAFAQ 347



>XP_006713174
          Length = 527

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LFRVFAQ 8
           LFR FAQ
Sbjct: 341 LFRAFAQ 347



>XP_005264800
          Length = 527

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   LFRVFAQ 8
           LFR FAQ
Sbjct: 341 LFRAFAQ 347



>NP_061891
          Length = 356

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   ILFRVFAQ 8
           +LF++F+Q
Sbjct: 144 VLFQIFSQ 151



>XP_006714032
          Length = 423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ILFRVFA 7
           ILF+VFA
Sbjct: 412 ILFQVFA 418



>NP_054733
          Length = 2136

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LFRVFAQS 9
            LFRVF+ S
Sbjct: 1014 LFRVFSLS 1021



>NP_000247
          Length = 1274

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FRVFAQS 9
            FRVF+Q+
Sbjct: 1137 FRVFSQN 1143



>NP_003310
          Length = 26926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 11278 FRVFAEN 11284




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 13361 FRVFAEN 13367




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 19948 FRVFAEN 19954




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 24006 FRVFAEN 24012



>NP_597676
          Length = 27051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 11403 FRVFAEN 11409




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 13486 FRVFAEN 13492




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 20073 FRVFAEN 20079




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 24131 FRVFAEN 24137



>NP_001243779
          Length = 34350

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 18702 FRVFAEN 18708




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 20785 FRVFAEN 20791




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 27372 FRVFAEN 27378




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 31430 FRVFAEN 31436



>NP_001252542
          Length = 331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FRVFAQS 9
           FRVFA++
Sbjct: 194 FRVFAEN 200



>NP_596869
          Length = 33423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 17775 FRVFAEN 17781




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 19858 FRVFAEN 19864




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 26445 FRVFAEN 26451




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 30503 FRVFAEN 30509



>NP_001010985
          Length = 354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FRVFAQS 9
           FRVFA++
Sbjct: 217 FRVFAEN 223



>XP_005260859
          Length = 545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ILFRVFAQ 8
           + FR FAQ
Sbjct: 523 VCFRTFAQ 530



>XP_005260858
          Length = 643

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ILFRVFAQ 8
           + FR FAQ
Sbjct: 523 VCFRTFAQ 530



>XP_005260857
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ILFRVFAQ 8
           + FR FAQ
Sbjct: 523 VCFRTFAQ 530



>XP_006723671
          Length = 684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ILFRVFAQ 8
           + FR FAQ
Sbjct: 523 VCFRTFAQ 530



>XP_006723670
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ILFRVFAQ 8
           + FR FAQ
Sbjct: 523 VCFRTFAQ 530



>XP_005260854
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ILFRVFAQ 8
           + FR FAQ
Sbjct: 523 VCFRTFAQ 530



>XP_006723669
          Length = 718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ILFRVFAQ 8
           + FR FAQ
Sbjct: 523 VCFRTFAQ 530



>XP_006718301
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FRVFAQS 9
            FRVF+Q+
Sbjct: 1131 FRVFSQN 1137



>XP_005246888
          Length = 22663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FRVFAQS 9
            FRVFA++
Sbjct: 7015 FRVFAEN 7021




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FRVFAQS 9
            FRVFA++
Sbjct: 9098 FRVFAEN 9104




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 15685 FRVFAEN 15691




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 19743 FRVFAEN 19749



>XP_006712788
          Length = 24022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    FRVFAQS 9
            FRVFA++
Sbjct: 8374 FRVFAEN 8380




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 10457 FRVFAEN 10463




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 17044 FRVFAEN 17050




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 21102 FRVFAEN 21108



>XP_006712787
          Length = 33978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 18330 FRVFAEN 18336




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 20413 FRVFAEN 20419




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 27000 FRVFAEN 27006




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 31058 FRVFAEN 31064



>XP_006712786
          Length = 35484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 19836 FRVFAEN 19842




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 21919 FRVFAEN 21925




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 28506 FRVFAEN 28512




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 32564 FRVFAEN 32570



>XP_006710676
          Length = 354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   FRVFAQS 9
           FRVFA++
Sbjct: 217 FRVFAEN 223



>NP_071927
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ILFRVFAQ 8
           + FR FAQ
Sbjct: 523 VCFRTFAQ 530



>NP_001254479
          Length = 35991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 20343 FRVFAEN 20349




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 22426 FRVFAEN 22432




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 29013 FRVFAEN 29019




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 33071 FRVFAEN 33077



>NP_597681
          Length = 27118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 11470 FRVFAEN 11476




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 13553 FRVFAEN 13559




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 20140 FRVFAEN 20146




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     FRVFAQS 9
             FRVFA++
Sbjct: 24198 FRVFAEN 24204



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.355    0.155    0.420 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 293,422
Number of extensions: 567
Number of successful extensions: 66
Number of sequences better than 10000.0: 36
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (17.0 bits)
S2: 28 (15.4 bits)