Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              20     509
XP_006718908                                                           20     509
XP_005271621                                                           20     509
XP_006718907                                                           20     509
XP_006718906                                                           20     509
XP_005271619                                                           20     509
XP_005271618                                                           20     509
NP_055090                                                              17    3301
NP_463459                                                              17    3301
NP_997191                                                              17    4312
NP_056093                                                              17    4312
XP_005266932                                                           17    4312
XP_006715469                                                           17    4312
XP_005266931                                                           17    4312
XP_006711682                                                           17    4312
NP_775859                                                              16    5631
NP_777578                                                              16    7355
NP_003310                                                              16    7355
NP_597676                                                              16    7355
NP_001243779                                                           16    7355
NP_705835                                                              16    7355
NP_001277251                                                           16    7355
NP_005500                                                              16    7355
NP_001277250                                                           16    7355
NP_001161866                                                           16    7355
NP_001161865                                                           16    7355
XP_005265878                                                           16    7355
XP_006714885                                                           16    7355
XP_005271970                                                           16    7355
XP_005271969                                                           16    7355
XP_005271967                                                           16    7355
XP_005271966                                                           16    7355
XP_006712787                                                           16    7355
XP_006712786                                                           16    7355
NP_001254479                                                           16    7355
NP_597681                                                              16    7355
NP_056044                                                              15    9605
NP_056078                                                              15    9605
NP_001167587                                                           15    9605
NP_001167588                                                           15    9605
NP_001979                                                              15    9605
NP_443111                                                              15    9605
NP_002423                                                              15    9605
NP_954660                                                              15    9605
NP_954658                                                              15    9605
NP_001164274                                                           15    9605
XP_006725233                                                           15    9605
XP_006725232                                                           15    9605
XP_006725231                                                           15    9605
XP_005256625                                                           15    9605
XP_005256624                                                           15    9605
XP_005256622                                                           15    9605
XP_006721555                                                           15    9605
XP_006721554                                                           15    9605
XP_005254315                                                           15    9605
XP_005254314                                                           15    9605
XP_006720509                                                           15    9605
XP_005254313                                                           15    9605
XP_005254312                                                           15    9605
XP_006720285                                                           15    9605
XP_005267988                                                           15    9605
XP_005267987                                                           15    9605
XP_006719279                                                           15    9605
XP_005268670                                                           15    9605
XP_006719278                                                           15    9605
NP_001164275                                                           15    9605
NP_001164279                                                           15    9605
NP_478144                                                              15    9605
NP_001094857                                                           15    9605
>NP_000042
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ILEIISKSP 9
            ILEI+SKSP
Sbjct: 1404 ILEILSKSP 1412
>XP_006718908
          Length = 1708

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  ILEIISKSP 9
          ILEI+SKSP
Sbjct: 56 ILEILSKSP 64
>XP_005271621
          Length = 2708

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ILEIISKSP 9
            ILEI+SKSP
Sbjct: 1056 ILEILSKSP 1064
>XP_006718907
          Length = 3050

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ILEIISKSP 9
            ILEI+SKSP
Sbjct: 1398 ILEILSKSP 1406
>XP_006718906
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ILEIISKSP 9
            ILEI+SKSP
Sbjct: 1404 ILEILSKSP 1412
>XP_005271619
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ILEIISKSP 9
            ILEI+SKSP
Sbjct: 1404 ILEILSKSP 1412
>XP_005271618
          Length = 3056

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ILEIISKSP 9
            ILEI+SKSP
Sbjct: 1404 ILEILSKSP 1412
>NP_055090
          Length = 548

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILEIISKSP 9
           +LE+IS SP
Sbjct: 211 LLEVISPSP 219
>NP_463459
          Length = 563

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILEIISKSP 9
           +LE+IS SP
Sbjct: 226 LLEVISPSP 234
>NP_997191
          Length = 1888

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LEIISKSP 9
            LE+IS SP
Sbjct: 1726 LEVISSSP 1733
>NP_056093
          Length = 1247

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILEIISKSP 9
           I++IISK P
Sbjct: 582 IIDIISKPP 590
>XP_005266932
          Length = 1008

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILEIISKSP 9
           I++IISK P
Sbjct: 343 IIDIISKPP 351
>XP_006715469
          Length = 1235

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILEIISKSP 9
           I++IISK P
Sbjct: 570 IIDIISKPP 578
>XP_005266931
          Length = 1283

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILEIISKSP 9
           I++IISK P
Sbjct: 618 IIDIISKPP 626
>XP_006711682
          Length = 1739

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LEIISKSP 9
            LE+IS SP
Sbjct: 1577 LEVISSSP 1584
>NP_775859
          Length = 1326

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ILEIISKSP 9
           +LEI+SK P
Sbjct: 191 MLEILSKVP 199
>NP_777578
          Length = 187

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ILEIISKSP 9
           ILE++ K P
Sbjct: 174 ILEVLQKMP 182
>NP_003310
          Length = 26926

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    LEIISKSP 9
            LE++S+SP
Sbjct: 3435 LELLSESP 3442
>NP_597676
          Length = 27051

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    LEIISKSP 9
            LE++S+SP
Sbjct: 3560 LELLSESP 3567
>NP_001243779
          Length = 34350

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    LEIISKSP 9
            LE++S+SP
Sbjct: 3481 LELLSESP 3488
>NP_705835
          Length = 639

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EIISKSP 9
           E+ISK+P
Sbjct: 131 EVISKTP 137
>NP_001277251
          Length = 2854

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LEIISKSP 9
            LE++SK P
Sbjct: 1702 LEVLSKMP 1709
>NP_005500
          Length = 3027

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LEIISKSP 9
            LE++SK P
Sbjct: 1875 LEVLSKMP 1882
>NP_001277250
          Length = 3048

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LEIISKSP 9
            LE++SK P
Sbjct: 1875 LEVLSKMP 1882
>NP_001161866
          Length = 417

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EIISKSP 9
           E+ISK+P
Sbjct: 131 EVISKTP 137
>NP_001161865
          Length = 417

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EIISKSP 9
           E+ISK+P
Sbjct: 131 EVISKTP 137
>XP_005265878
          Length = 631

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EIISKSP 9
           E+ISK+P
Sbjct: 123 EVISKTP 129
>XP_006714885
          Length = 639

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EIISKSP 9
           E+ISK+P
Sbjct: 131 EVISKTP 137
>XP_005271970
          Length = 2931

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LEIISKSP 9
            LE++SK P
Sbjct: 1875 LEVLSKMP 1882
>XP_005271969
          Length = 3020

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LEIISKSP 9
            LE++SK P
Sbjct: 1809 LEVLSKMP 1816
>XP_005271967
          Length = 3065

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LEIISKSP 9
            LE++SK P
Sbjct: 1875 LEVLSKMP 1882
>XP_005271966
          Length = 3086

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LEIISKSP 9
            LE++SK P
Sbjct: 1875 LEVLSKMP 1882
>XP_006712787
          Length = 33978

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    LEIISKSP 9
            LE++S+SP
Sbjct: 3482 LELLSESP 3489
>XP_006712786
          Length = 35484

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    LEIISKSP 9
            LE++S+SP
Sbjct: 3482 LELLSESP 3489
>NP_001254479
          Length = 35991

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    LEIISKSP 9
            LE++S+SP
Sbjct: 3798 LELLSESP 3805
>NP_597681
          Length = 27118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    LEIISKSP 9
            LE++S+SP
Sbjct: 3627 LELLSESP 3634
>NP_056044
          Length = 1309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ILEIISKSP 9
           +LE++ +SP
Sbjct: 792 VLELVLRSP 800
>NP_056078
          Length = 3036

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LEIISKSP 9
            LE++SK P
Sbjct: 1902 LEVLSKIP 1909
>NP_001167587
          Length = 3037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LEIISKSP 9
            LE++SK P
Sbjct: 1902 LEVLSKIP 1909
>NP_001167588
          Length = 2400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LEIISKSP 9
            LE++SK P
Sbjct: 1266 LEVLSKIP 1273
>NP_001979
          Length = 2033

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    IISKSP 9
            IISKSP
Sbjct: 1795 IISKSP 1800
>NP_443111
          Length = 724

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ILEIISKSP 9
           ILE++  SP
Sbjct: 173 ILEVLRSSP 181
>NP_002423
          Length = 407

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ILEIISKSP 9
           I+EI +K+P
Sbjct: 299 IIEIANKTP 307
>NP_954660
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ILEIISKSP 9
           ILE++  SP
Sbjct: 173 ILEVLRSSP 181
>NP_954658
          Length = 723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ILEIISKSP 9
           ILE++  SP
Sbjct: 172 ILEVLRSSP 180
>NP_001164274
          Length = 582

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ILEIISKSP 9
           ILE++  SP
Sbjct: 173 ILEVLRSSP 181
>XP_006725233
          Length = 766

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILEIISKS 8
           I+EI SKS
Sbjct: 486 IIEIFSKS 493
>XP_006725232
          Length = 766

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILEIISKS 8
           I+EI SKS
Sbjct: 486 IIEIFSKS 493
>XP_006725231
          Length = 766

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILEIISKS 8
           I+EI SKS
Sbjct: 486 IIEIFSKS 493
>XP_005256625
          Length = 1347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ILEIISKSP 9
           +LE++ +SP
Sbjct: 830 VLELVLRSP 838
>XP_005256624
          Length = 1348

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ILEIISKSP 9
           +LE++ +SP
Sbjct: 831 VLELVLRSP 839
>XP_005256622
          Length = 1383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ILEIISKSP 9
           +LE++ +SP
Sbjct: 866 VLELVLRSP 874
>XP_006721555
          Length = 1444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ILEIISKSP 9
           +LE++ +SP
Sbjct: 927 VLELVLRSP 935
>XP_006721554
          Length = 1445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   ILEIISKSP 9
           +LE++ +SP
Sbjct: 928 VLELVLRSP 936
>XP_005254315
          Length = 2576

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LEIISKSP 9
            LE++SK P
Sbjct: 1902 LEVLSKIP 1909
>XP_005254314
          Length = 2605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LEIISKSP 9
            LE++SK P
Sbjct: 1902 LEVLSKIP 1909
>XP_006720509
          Length = 2646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LEIISKSP 9
            LE++SK P
Sbjct: 1902 LEVLSKIP 1909
>XP_005254313
          Length = 3057

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LEIISKSP 9
            LE++SK P
Sbjct: 1902 LEVLSKIP 1909
>XP_005254312
          Length = 3058

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LEIISKSP 9
            LE++SK P
Sbjct: 1902 LEVLSKIP 1909
>XP_006720285
          Length = 766

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILEIISKS 8
           I+EI SKS
Sbjct: 486 IIEIFSKS 493
>XP_005267988
          Length = 766

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILEIISKS 8
           I+EI SKS
Sbjct: 486 IIEIFSKS 493
>XP_005267987
          Length = 766

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILEIISKS 8
           I+EI SKS
Sbjct: 486 IIEIFSKS 493
>XP_006719279
          Length = 402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ILEIISKSP 9
           ILE++  SP
Sbjct: 173 ILEVLRSSP 181
>XP_005268670
          Length = 654

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ILEIISKSP 9
           ILE++  SP
Sbjct: 103 ILEVLRSSP 111
>XP_006719278
          Length = 670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ILEIISKSP 9
           ILE++  SP
Sbjct: 173 ILEVLRSSP 181
>NP_001164275
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ILEIISKSP 9
           ILE++  SP
Sbjct: 173 ILEVLRSSP 181
>NP_001164279
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ILEIISKSP 9
           ILE++  SP
Sbjct: 173 ILEVLRSSP 181
>NP_478144
          Length = 873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ILEIISKS 8
           I+EI SKS
Sbjct: 593 IIEIFSKS 600
>NP_001094857
          Length = 137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  ILEIISKSP 9
          +LE+  KSP
Sbjct: 9  VLEVDEKSP 17
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.137    0.340 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 497,924
Number of extensions: 1145
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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