Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              19     665
XP_006714104                                                           19     665
XP_005265800                                                           19     665
XP_006714103                                                           19     665
XP_006714102                                                           19     665
NP_006800                                                              17    2528
XP_005260311                                                           17    2528
NP_085132                                                              17    4312
NP_938204                                                              17    4312
NP_056127                                                              17    4312
XP_006721348                                                           17    4312
XP_005256239                                                           17    4312
XP_005256238                                                           17    4312
XP_005256236                                                           17    4312
XP_006714407                                                           17    4312
XP_006714405                                                           17    4312
XP_005263349                                                           17    4312
XP_005263348                                                           17    4312
XP_005263347                                                           17    4312
XP_005263346                                                           17    4312
XP_005263345                                                           17    4312
XP_005263344                                                           17    4312
XP_005263343                                                           17    4312
XP_005263342                                                           17    4312
XP_005263341                                                           17    4312
XP_005263340                                                           17    4312
XP_005263339                                                           17    4312
NP_870998                                                              16    5631
XP_005259168                                                           16    5631
XP_005270416                                                           16    5631
NP_001129162                                                           16    7355
NP_006202                                                              16    7355
NP_872384                                                              16    7355
NP_612429                                                              16    7355
NP_060141                                                              16    7355
NP_001171705                                                           16    7355
NP_001171706                                                           16    7355
NP_001171702                                                           16    7355
NP_001171703                                                           16    7355
NP_001171704                                                           16    7355
XP_006724259                                                           16    7355
XP_005261497                                                           16    7355
XP_005261496                                                           16    7355
XP_006724258                                                           16    7355
XP_005267356                                                           16    7355
XP_005245152                                                           16    7355
NP_066938                                                              16    7355
NP_006423                                                              15    9605
NP_073619                                                              15    9605
NP_001914                                                              15    9605
NP_001091954                                                           15    9605
NP_003750                                                              15    9605
NP_079446                                                              15    9605
NP_079146                                                              15    9605
NP_620584                                                              15    9605
NP_006460                                                              15    9605
NP_001161213                                                           15    9605
XP_006720067                                                           15    9605
XP_005253898                                                           15    9605
XP_006719254                                                           15    9605
XP_006719253                                                           15    9605
XP_006719252                                                           15    9605
XP_006719251                                                           15    9605
XP_005248552                                                           15    9605
XP_006714462                                                           15    9605
XP_006714461                                                           15    9605
XP_005265761                                                           15    9605
NP_060822                                                              15    9605
>NP_006197
          Length = 1089

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   IKLPSIKLV 9
           IK+PSIKLV
Sbjct: 264 IKVPSIKLV 272
>XP_006714104
          Length = 832

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   IKLPSIKLV 9
           IK+PSIKLV
Sbjct: 289 IKVPSIKLV 297
>XP_005265800
          Length = 1089

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   IKLPSIKLV 9
           IK+PSIKLV
Sbjct: 264 IKVPSIKLV 272
>XP_006714103
          Length = 1111

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   IKLPSIKLV 9
           IK+PSIKLV
Sbjct: 286 IKVPSIKLV 294
>XP_006714102
          Length = 1114

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   IKLPSIKLV 9
           IK+PSIKLV
Sbjct: 289 IKVPSIKLV 297
>NP_006800
          Length = 309

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   IKLPSIKLV 9
           +KLPSI LV
Sbjct: 142 LKLPSIPLV 150
>XP_005260311
          Length = 207

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  IKLPSIKLV 9
          +KLPSI LV
Sbjct: 40 LKLPSIPLV 48
>NP_085132
          Length = 679

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IKLPSIK 7
           IKLPS+K
Sbjct: 589 IKLPSLK 595
>NP_938204
          Length = 773

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IKLPSIK 7
           IKLPS+K
Sbjct: 683 IKLPSLK 689
>NP_056127
          Length = 5005

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IKLPSIKLV 9
            +KLPS+ LV
Sbjct: 4068 LKLPSLDLV 4076
>XP_006721348
          Length = 586

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IKLPSIK 7
           IKLPS+K
Sbjct: 496 IKLPSLK 502
>XP_005256239
          Length = 586

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IKLPSIK 7
           IKLPS+K
Sbjct: 496 IKLPSLK 502
>XP_005256238
          Length = 586

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IKLPSIK 7
           IKLPS+K
Sbjct: 496 IKLPSLK 502
>XP_005256236
          Length = 737

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   IKLPSIK 7
           IKLPS+K
Sbjct: 647 IKLPSLK 653
>XP_006714407
          Length = 5004

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IKLPSIKLV 9
            +KLPS+ LV
Sbjct: 4067 LKLPSLDLV 4075
>XP_006714405
          Length = 4103

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IKLPSIKLV 9
            +KLPS+ LV
Sbjct: 3166 LKLPSLDLV 3174
>XP_005263349
          Length = 4410

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IKLPSIKLV 9
            +KLPS+ LV
Sbjct: 3473 LKLPSLDLV 3481
>XP_005263348
          Length = 4443

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IKLPSIKLV 9
            +KLPS+ LV
Sbjct: 3506 LKLPSLDLV 3514
>XP_005263347
          Length = 4640

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IKLPSIKLV 9
            +KLPS+ LV
Sbjct: 4089 LKLPSLDLV 4097
>XP_005263346
          Length = 4983

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IKLPSIKLV 9
            +KLPS+ LV
Sbjct: 4046 LKLPSLDLV 4054
>XP_005263345
          Length = 4991

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IKLPSIKLV 9
            +KLPS+ LV
Sbjct: 4054 LKLPSLDLV 4062
>XP_005263344
          Length = 5005

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IKLPSIKLV 9
            +KLPS+ LV
Sbjct: 4068 LKLPSLDLV 4076
>XP_005263343
          Length = 5009

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IKLPSIKLV 9
            +KLPS+ LV
Sbjct: 4072 LKLPSLDLV 4080
>XP_005263342
          Length = 5025

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IKLPSIKLV 9
            +KLPS+ LV
Sbjct: 4088 LKLPSLDLV 4096
>XP_005263341
          Length = 5026

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IKLPSIKLV 9
            +KLPS+ LV
Sbjct: 4089 LKLPSLDLV 4097
>XP_005263340
          Length = 5026

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IKLPSIKLV 9
            +KLPS+ LV
Sbjct: 4089 LKLPSLDLV 4097
>XP_005263339
          Length = 5026

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    IKLPSIKLV 9
            +KLPS+ LV
Sbjct: 4089 LKLPSLDLV 4097
>NP_870998
          Length = 1461

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IKLPSIKL 8
           +KLP+IK+
Sbjct: 415 LKLPTIKM 422

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IKLPSIKL 8
           +KLP IKL
Sbjct: 722 MKLPEIKL 729

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IKLPSIKL 8
           +KLP +KL
Sbjct: 634 MKLPEVKL 641
>XP_005259168
          Length = 1435

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IKLPSIKL 8
           +KLP+IK+
Sbjct: 415 LKLPTIKM 422

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   IKLPSIKL 8
           +KLP IKL
Sbjct: 696 MKLPEIKL 703

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IKLPSIKL 8
           +KLP +KL
Sbjct: 608 MKLPEVKL 615
>XP_005270416
          Length = 805

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KLPSIKLV 9
           KLPS+K++
Sbjct: 788 KLPSLKIL 795
>NP_001129162
          Length = 267

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  KLPSIKL 8
          KLPS+K+
Sbjct: 55 KLPSLKI 61
>NP_006202
          Length = 267

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  KLPSIKL 8
          KLPS+K+
Sbjct: 55 KLPSLKI 61
>NP_872384
          Length = 247

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  IKLPSIK 7
          IKLPS K
Sbjct: 83 IKLPSFK 89
>NP_612429
          Length = 5795

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    IKLPSIKL 8
            +K+P IKL
Sbjct: 4953 LKMPKIKL 4960
>NP_060141
          Length = 677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   IKLPSIKLV 9
           ++LP++K+V
Sbjct: 99  LRLPNLKMV 107
>NP_001171705
          Length = 949

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KLPSIKLV 9
           KLPS+K V
Sbjct: 118 KLPSLKQV 125
>NP_001171706
          Length = 948

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KLPSIKLV 9
           KLPS+K V
Sbjct: 118 KLPSLKQV 125
>NP_001171702
          Length = 1023

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KLPSIKLV 9
           KLPS+K V
Sbjct: 118 KLPSLKQV 125
>NP_001171703
          Length = 1013

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KLPSIKLV 9
           KLPS+K V
Sbjct: 118 KLPSLKQV 125
>NP_001171704
          Length = 1011

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KLPSIKLV 9
           KLPS+K V
Sbjct: 118 KLPSLKQV 125
>XP_006724259
          Length = 947

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KLPSIKLV 9
           KLPS+K V
Sbjct: 118 KLPSLKQV 125
>XP_005261497
          Length = 960

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KLPSIKLV 9
           KLPS+K V
Sbjct: 118 KLPSLKQV 125
>XP_005261496
          Length = 1012

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KLPSIKLV 9
           KLPS+K V
Sbjct: 118 KLPSLKQV 125
>XP_006724258
          Length = 1022

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KLPSIKLV 9
           KLPS+K V
Sbjct: 118 KLPSLKQV 125
>XP_005267356
          Length = 5695

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    IKLPSIKL 8
            +K+P IKL
Sbjct: 4853 LKMPKIKL 4860
>XP_005245152
          Length = 247

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  IKLPSIK 7
          IKLPS K
Sbjct: 83 IKLPSFK 89
>NP_066938
          Length = 1024

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KLPSIKLV 9
           KLPS+K V
Sbjct: 118 KLPSLKQV 125
>NP_006423
          Length = 151

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   PSIKLV 9
           PSIKLV
Sbjct: 120 PSIKLV 125
>NP_073619
          Length = 1183

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IKLPSIK 7
           +KLPS+K
Sbjct: 405 MKLPSLK 411
>NP_001914
          Length = 1140

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   IKLPSIKLV 9
           +KLPS +L+
Sbjct: 569 LKLPSFELL 577
>NP_001091954
          Length = 1079

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    KLPSIKL 8
            K+PSIK+
Sbjct: 1041 KVPSIKI 1047
>NP_003750
          Length = 1035

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    KLPSIKL 8
            K+PSIK+
Sbjct: 997  KVPSIKI 1003
>NP_079446
          Length = 979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KLPSIKLV 9
           K+P IKLV
Sbjct: 612 KVPIIKLV 619
>NP_079146
          Length = 1606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KLPSIKLV 9
           K+P IKLV
Sbjct: 612 KVPIIKLV 619
>NP_620584
          Length = 384

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   IKLPSIKL 8
           ++LPS+K+
Sbjct: 181 VRLPSLKV 188
>NP_006460
          Length = 642

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IKLPSIKL 8
           +KLP +KL
Sbjct: 171 LKLPRLKL 178
>NP_001161213
          Length = 251

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KLPSIKL 8
           KLP++KL
Sbjct: 230 KLPTLKL 236
>XP_006720067
          Length = 174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   PSIKLV 9
           PSIKLV
Sbjct: 120 PSIKLV 125
>XP_005253898
          Length = 347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   IKLPSIKL 8
           ++LPS+K+
Sbjct: 144 VRLPSLKV 151
>XP_006719254
          Length = 810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  IKLPSIK 7
          +KLPS+K
Sbjct: 32 MKLPSLK 38
>XP_006719253
          Length = 1031

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IKLPSIK 7
           +KLPS+K
Sbjct: 253 MKLPSLK 259
>XP_006719252
          Length = 1031

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IKLPSIK 7
           +KLPS+K
Sbjct: 253 MKLPSLK 259
>XP_006719251
          Length = 1116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IKLPSIK 7
           +KLPS+K
Sbjct: 338 MKLPSLK 344
>XP_005248552
          Length = 312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KLPSIKL 8
           KLP++KL
Sbjct: 291 KLPTLKL 297
>XP_006714462
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    KLPSIKL 8
            K+PSIK+
Sbjct: 1046 KVPSIKI 1052
>XP_006714461
          Length = 1099

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    KLPSIKL 8
            K+PSIK+
Sbjct: 1061 KVPSIKI 1067
>XP_005265761
          Length = 1110

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    KLPSIKL 8
            K+PSIK+
Sbjct: 1072 KVPSIKI 1078
>NP_060822
          Length = 203

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KLPSIKL 8
           KLP+IK+
Sbjct: 152 KLPNIKM 158
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.148    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 643,402
Number of extensions: 922
Number of successful extensions: 72
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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