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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              20     390
XP_006716142                                                           20     390
XP_005250088                                                           20     390
XP_006716141                                                           20     390
XP_005250085                                                           20     390
XP_006716140                                                           20     390
XP_005250084                                                           20     390
XP_005250083                                                           20     390
XP_005250082                                                           20     390
NP_660286                                                              17    4312
NP_001269221" target = "next">NP_001269221                                                           16    5631
NP_009119                                                              16    5631
NP_001269220" target = "next">NP_001269220                                                           16    5631
NP_001269222" target = "next">NP_001269222                                                           16    5631
XP_006718613                                                           16    5631
XP_006717120                                                           16    5631
XP_006717119                                                           16    5631
XP_005266123                                                           16    5631
NP_976221                                                              16    7355
NP_001230829                                                           16    7355
NP_005327                                                              16    7355
XP_005260751                                                           16    7355
XP_005258622                                                           16    7355
XP_006712539                                                           16    7355
XP_005247059                                                           16    7355
XP_005247058                                                           16    7355
XP_006712538                                                           16    7355
XP_005247060                                                           16    7355
XP_005247057                                                           16    7355
NP_001269                                                              15    9605
NP_001073964                                                           15    9605
NP_055828                                                              15    9605
NP_001009999                                                           15    9605
NP_775321                                                              15    9605
NP_115805                                                              15    9605
NP_001106649                                                           15    9605
NP_619728                                                              15    9605
NP_006590                                                              15    9605
NP_619727                                                              15    9605
NP_775322                                                              15    9605
NP_001269836                                                           15    9605
NP_001269837                                                           15    9605
NP_001269838                                                           15    9605
NP_006576                                                              15    9605
NP_853517                                                              15    9605
NP_002554                                                              15    9605
NP_001229686                                                           15    9605
XP_006724707                                                           15    9605
XP_006721927                                                           15    9605
XP_005257364                                                           15    9605
XP_006721210                                                           15    9605
XP_006721209                                                           15    9605
XP_006721208                                                           15    9605
XP_006721188                                                           15    9605
XP_005270281                                                           15    9605
XP_005270279                                                           15    9605
XP_005270280                                                           15    9605
XP_006715861                                                           15    9605
XP_006715860                                                           15    9605
XP_006714258                                                           15    9605
XP_006710537                                                           15    9605
XP_006710536                                                           15    9605
XP_006710535                                                           15    9605
XP_005245843                                                           15    9605

>NP_733751
          Length = 4911

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IIGSGVRKS 9
            I+GSGVRKS
Sbjct: 4205 ILGSGVRKS 4213



>XP_006716142
          Length = 4927

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IIGSGVRKS 9
            I+GSGVRKS
Sbjct: 4221 ILGSGVRKS 4229



>XP_005250088
          Length = 4928

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IIGSGVRKS 9
            I+GSGVRKS
Sbjct: 4222 ILGSGVRKS 4230



>XP_006716141
          Length = 4959

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IIGSGVRKS 9
            I+GSGVRKS
Sbjct: 4253 ILGSGVRKS 4261



>XP_005250085
          Length = 4979

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IIGSGVRKS 9
            I+GSGVRKS
Sbjct: 4277 ILGSGVRKS 4285



>XP_006716140
          Length = 4982

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IIGSGVRKS 9
            I+GSGVRKS
Sbjct: 4276 ILGSGVRKS 4284



>XP_005250084
          Length = 4982

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IIGSGVRKS 9
            I+GSGVRKS
Sbjct: 4276 ILGSGVRKS 4284



>XP_005250083
          Length = 4982

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IIGSGVRKS 9
            I+GSGVRKS
Sbjct: 4276 ILGSGVRKS 4284



>XP_005250082
          Length = 4983

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    IIGSGVRKS 9
            I+GSGVRKS
Sbjct: 4277 ILGSGVRKS 4285



>NP_660286
          Length = 524

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   IIGSGVRK 8
           I+G G+RK
Sbjct: 164 IVGRGIRK 171



>NP_001269221" target = "next">NP_001269221
          Length = 693

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IIGSGVRK 8
           ++GSG+RK
Sbjct: 294 LMGSGLRK 301



>NP_009119
          Length = 718

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IIGSGVRK 8
           ++GSG+RK
Sbjct: 294 LMGSGLRK 301



>NP_001269220" target = "next">NP_001269220
          Length = 735

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IIGSGVRK 8
           ++GSG+RK
Sbjct: 311 LMGSGLRK 318



>NP_001269222" target = "next">NP_001269222
          Length = 630

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   IIGSGVRK 8
           ++GSG+RK
Sbjct: 206 LMGSGLRK 213



>XP_006718613
          Length = 1946

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IGSGVRKS 9
           +G GVR+S
Sbjct: 566 VGGGVRRS 573



>XP_006717120
          Length = 555

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IIGSGVR 7
           I+GSG+R
Sbjct: 166 ILGSGIR 172



>XP_006717119
          Length = 615

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IIGSGVR 7
           I+GSG+R
Sbjct: 235 ILGSGIR 241



>XP_005266123
          Length = 624

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   IIGSGVR 7
           I+GSG+R
Sbjct: 235 ILGSGIR 241



>NP_976221
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   GSGVRK 8
           GSG+RK
Sbjct: 992 GSGIRK 997



>NP_001230829
          Length = 1235

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   GSGVRK 8
           GSG+RK
Sbjct: 959 GSGIRK 964



>NP_005327
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   GSGVRK 8
           GSG+RK
Sbjct: 992 GSGIRK 997



>XP_005260751
          Length = 1060

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  IIGSGVRKS 9
          I+G G+R+S
Sbjct: 23 ILGKGLRES 31



>XP_005258622
          Length = 592

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  IIGSGVR 7
          I+GSG+R
Sbjct: 12 IVGSGLR 18



>XP_006712539
          Length = 1250

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   GSGVRK 8
           GSG+RK
Sbjct: 992 GSGIRK 997



>XP_005247059
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   GSGVRK 8
           GSG+RK
Sbjct: 992 GSGIRK 997



>XP_005247058
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   GSGVRK 8
           GSG+RK
Sbjct: 992 GSGIRK 997



>XP_006712538
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   GSGVRK 8
           GSG+RK
Sbjct: 992 GSGIRK 997



>XP_005247060
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   GSGVRK 8
           GSG+RK
Sbjct: 992 GSGIRK 997



>XP_005247057
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   GSGVRK 8
           GSG+RK
Sbjct: 992 GSGIRK 997



>NP_001269
          Length = 745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   IGSGVR 7
           IGSG+R
Sbjct: 128 IGSGIR 133



>NP_001073964
          Length = 2968

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    IGSGVRK 8
            +G+G+RK
Sbjct: 1568 LGAGIRK 1574



>NP_055828
          Length = 852

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   IIGSGV 6
           IIGSGV
Sbjct: 283 IIGSGV 288



>NP_001009999
          Length = 876

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   IIGSGV 6
           IIGSGV
Sbjct: 303 IIGSGV 308



>NP_775321
          Length = 1455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GSGVRKS 9
           G+GV+KS
Sbjct: 184 GTGVKKS 190



>NP_115805
          Length = 669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   IIGSGVRKS 9
           ++GSG R S
Sbjct: 293 LLGSGTRAS 301



>NP_001106649
          Length = 1548

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GSGVRKS 9
           G+GV+KS
Sbjct: 278 GTGVKKS 284



>NP_619728
          Length = 1455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GSGVRKS 9
           G+GV+KS
Sbjct: 184 GTGVKKS 190



>NP_006590
          Length = 1531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GSGVRKS 9
           G+GV+KS
Sbjct: 260 GTGVKKS 266



>NP_619727
          Length = 1549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GSGVRKS 9
           G+GV+KS
Sbjct: 278 GTGVKKS 284



>NP_775322
          Length = 1455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GSGVRKS 9
           G+GV+KS
Sbjct: 184 GTGVKKS 190



>NP_001269836
          Length = 529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   IIGSGVRKS 9
           I+GSG+  S
Sbjct: 188 ILGSGISSS 196



>NP_001269837
          Length = 497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   IIGSGVRKS 9
           I+GSG+  S
Sbjct: 156 ILGSGISSS 164



>NP_001269838
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   IIGSGVRKS 9
           I+GSG+  S
Sbjct: 134 ILGSGISSS 142



>NP_006576
          Length = 548

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   IIGSGVRKS 9
           I+GSG+  S
Sbjct: 207 ILGSGISSS 215



>NP_853517
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  IGSGVRKS 9
          +GSG R S
Sbjct: 35 VGSGARSS 42



>NP_002554
          Length = 373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GSGVRKS 9
           G+GVRK+
Sbjct: 191 GTGVRKN 197



>NP_001229686
          Length = 338

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   IIGSGVRKS 9
           ++G G+R S
Sbjct: 129 LVGGGIRAS 137



>XP_006724707
          Length = 1337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   IIGSGVRKS 9
           ++G+GV++S
Sbjct: 140 VLGNGVQES 148



>XP_006721927
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  IGSGVRKS 9
          +GSG R S
Sbjct: 35 VGSGARSS 42



>XP_005257364
          Length = 466

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  IGSGVRKS 9
          +GSG R S
Sbjct: 35 VGSGARSS 42



>XP_006721210
          Length = 371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   IIGSGVRKS 9
           ++G G+R S
Sbjct: 162 LVGGGIRAS 170



>XP_006721209
          Length = 331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   IIGSGVRKS 9
           ++G G+R S
Sbjct: 129 LVGGGIRAS 137



>XP_006721208
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   IIGSGVRKS 9
           ++G G+R S
Sbjct: 162 LVGGGIRAS 170



>XP_006721188
          Length = 1484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GSGVRKS 9
           G+GV+KS
Sbjct: 213 GTGVKKS 219



>XP_005270281
          Length = 669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   IIGSGVRKS 9
           ++GSG R S
Sbjct: 293 LLGSGTRAS 301



>XP_005270279
          Length = 669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   IIGSGVRKS 9
           ++GSG R S
Sbjct: 293 LLGSGTRAS 301



>XP_005270280
          Length = 669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   IIGSGVRKS 9
           ++GSG R S
Sbjct: 293 LLGSGTRAS 301



>XP_006715861
          Length = 2189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    IGSGVRK 8
            +G+G+RK
Sbjct: 1568 LGAGIRK 1574



>XP_006715860
          Length = 2968

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    IGSGVRK 8
            +G+G+RK
Sbjct: 1568 LGAGIRK 1574



>XP_006714258
          Length = 994

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IGSGVRKS 9
           +G GVRK+
Sbjct: 409 LGRGVRKN 416



>XP_006710537
          Length = 878

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   IIGSGV 6
           IIGSGV
Sbjct: 303 IIGSGV 308



>XP_006710536
          Length = 828

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   IIGSGV 6
           IIGSGV
Sbjct: 303 IIGSGV 308



>XP_006710535
          Length = 858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   IIGSGV 6
           IIGSGV
Sbjct: 283 IIGSGV 288



>XP_005245843
          Length = 872

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   IIGSGV 6
           IIGSGV
Sbjct: 303 IIGSGV 308



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.140    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 633,950
Number of extensions: 1080
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)