Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_036284                                                              17    3301
XP_006710605                                                           17    3301
NP_072179                                                              17    4312
NP_002881                                                              17    4312
NP_000292                                                              17    4312
NP_001269609                                                           17    4312
NP_001269608                                                           17    4312
NP_689804                                                              17    4312
NP_001273173                                                           17    4312
NP_001273172                                                           17    4312
XP_006719326                                                           17    4312
XP_006719325                                                           17    4312
XP_005251961                                                           17    4312
XP_006717106                                                           17    4312
XP_006717105                                                           17    4312
XP_005251958                                                           17    4312
NP_068380                                                              16    5631
NP_001119593                                                           16    5631
NP_001119594                                                           16    5631
NP_001005466                                                           16    5631
NP_001166953                                                           16    5631
NP_057386                                                              16    5631
NP_002514                                                              16    5631
NP_001243257                                                           16    5631
NP_938406                                                              16    5631
NP_938191                                                              16    5631
NP_061496                                                              16    5631
NP_938197                                                              16    5631
NP_938200                                                              16    5631
NP_938194                                                              16    5631
NP_001243289                                                           16    5631
NP_938202                                                              16    5631
NP_938199                                                              16    5631
NP_938192                                                              16    5631
NP_001243255                                                           16    5631
NP_938193                                                              16    5631
NP_001243290                                                           16    5631
NP_001243258                                                           16    5631
NP_001243254                                                           16    5631
NP_938201                                                              16    5631
NP_001243261                                                           16    5631
NP_001243259                                                           16    5631
NP_938196                                                              16    5631
NP_938198                                                              16    5631
NP_001243256                                                           16    5631
NP_001243260                                                           16    5631
NP_001243288                                                           16    5631
NP_001243253                                                           16    5631
NP_003250                                                              16    5631
XP_006722224                                                           16    5631
XP_006722223                                                           16    5631
XP_005257619                                                           16    5631
XP_006722070                                                           16    5631
XP_005257617                                                           16    5631
XP_005257618                                                           16    5631
XP_005257616                                                           16    5631
XP_005265259                                                           16    5631
NP_001273700                                                           16    7355
NP_115593                                                              16    7355
NP_942592                                                              16    7355
XP_005265728                                                           16    7355
XP_005265724                                                           16    7355
NP_001269796                                                           15    9605
NP_001269800                                                           15    9605
NP_001269801                                                           15    9605
NP_001269799                                                           15    9605
NP_001121163                                                           15    9605
NP_057208                                                              15    9605
NP_001269797                                                           15    9605
NP_001269798                                                           15    9605
NP_060695                                                              15    9605
NP_056083                                                              15    9605
XP_005251560                                                           15    9605
XP_005247302                                                           15    9605
NP_899234                                                              15    9605
>NP_036284
          Length = 353

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  GKVSKTLT 9
          G VSKTLT
Sbjct: 91 GPVSKTLT 98
>XP_006710605
          Length = 353

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  GKVSKTLT 9
          G VSKTLT
Sbjct: 91 GPVSKTLT 98
>NP_072179
          Length = 870

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   HGKVSK 6
           HGK+SK
Sbjct: 176 HGKISK 181
>NP_002881
          Length = 1047

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   HGKVSK 6
           HGK+SK
Sbjct: 353 HGKISK 358
>NP_000292
          Length = 810

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GKVSKTLT 9
           GK+SKT++
Sbjct: 195 GKISKTMS 202
>NP_001269609
          Length = 1460

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   HGKVSKTL 8
           HGK  KTL
Sbjct: 556 HGKPDKTL 563
>NP_001269608
          Length = 1478

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   HGKVSKTL 8
           HGK  KTL
Sbjct: 556 HGKPDKTL 563
>NP_689804
          Length = 563

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   HGKVSKTL 8
           +G+VSKTL
Sbjct: 400 YGEVSKTL 407
>NP_001273173
          Length = 484

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   HGKVSKTL 8
           +G+VSKTL
Sbjct: 321 YGEVSKTL 328
>NP_001273172
          Length = 523

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   HGKVSKTL 8
           +G+VSKTL
Sbjct: 360 YGEVSKTL 367
>XP_006719326
          Length = 539

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   HGKVSKTL 8
           +G+VSKTL
Sbjct: 400 YGEVSKTL 407
>XP_006719325
          Length = 563

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   HGKVSKTL 8
           +G+VSKTL
Sbjct: 400 YGEVSKTL 407
>XP_005251961
          Length = 1433

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   HGKVSKTL 8
           HGK  KTL
Sbjct: 556 HGKPDKTL 563
>XP_006717106
          Length = 1460

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   HGKVSKTL 8
           HGK  KTL
Sbjct: 556 HGKPDKTL 563
>XP_006717105
          Length = 1460

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   HGKVSKTL 8
           HGK  KTL
Sbjct: 556 HGKPDKTL 563
>XP_005251958
          Length = 1460

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   HGKVSKTL 8
           HGK  KTL
Sbjct: 556 HGKPDKTL 563
>NP_068380
          Length = 320

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GKVSKTLT 9
           G +SKTLT
Sbjct: 227 GVISKTLT 234
>NP_001119593
          Length = 320

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GKVSKTLT 9
           G +SKTLT
Sbjct: 227 GVISKTLT 234
>NP_001119594
          Length = 320

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GKVSKTLT 9
           G +SKTLT
Sbjct: 227 GVISKTLT 234
>NP_001005466
          Length = 310

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HGKVSKTLT 9
           HG +  TLT
Sbjct: 160 HGSIQATLT 168
>NP_001166953
          Length = 441

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   HGKVSKTLT 9
           HG V +TLT
Sbjct: 352 HGYVHETLT 360
>NP_057386
          Length = 442

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   HGKVSKTLT 9
           HG V +TLT
Sbjct: 353 HGYVHETLT 361
>NP_002514
          Length = 431

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HGKVSKTL 8
           +GK+ KTL
Sbjct: 237 YGKIKKTL 244
>NP_001243257
          Length = 2259

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2066 HSKISKHMT 2074
>NP_938406
          Length = 2343

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2150 HSKISKHMT 2158
>NP_938191
          Length = 2366

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2173 HSKISKHMT 2181
>NP_061496
          Length = 2377

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2184 HSKISKHMT 2192
>NP_938197
          Length = 2306

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2113 HSKISKHMT 2121
>NP_938200
          Length = 2266

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2073 HSKISKHMT 2081
>NP_938194
          Length = 2321

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2128 HSKISKHMT 2136
>NP_001243289
          Length = 2248

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2055 HSKISKHMT 2063
>NP_938202
          Length = 2243

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2050 HSKISKHMT 2058
>NP_938199
          Length = 2332

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2139 HSKISKHMT 2147
>NP_938192
          Length = 2273

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2080 HSKISKHMT 2088
>NP_001243255
          Length = 2287

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2094 HSKISKHMT 2102
>NP_938193
          Length = 2298

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2105 HSKISKHMT 2113
>NP_001243290
          Length = 2246

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2053 HSKISKHMT 2061
>NP_001243258
          Length = 2250

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2057 HSKISKHMT 2065
>NP_001243254
          Length = 2291

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2098 HSKISKHMT 2106
>NP_938201
          Length = 2250

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2057 HSKISKHMT 2065
>NP_001243261
          Length = 2227

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2034 HSKISKHMT 2042
>NP_001243259
          Length = 2239

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2046 HSKISKHMT 2054
>NP_938196
          Length = 2261

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2068 HSKISKHMT 2076
>NP_938198
          Length = 2284

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2091 HSKISKHMT 2099
>NP_001243256
          Length = 2277

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2084 HSKISKHMT 2092
>NP_001243260
          Length = 2232

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2039 HSKISKHMT 2047
>NP_001243288
          Length = 2257

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2064 HSKISKHMT 2072
>NP_001243253
          Length = 2314

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2121 HSKISKHMT 2129
>NP_003250
          Length = 924

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   HGKVSKTL 8
           HG V+KT+
Sbjct: 651 HGSVAKTV 658
>XP_006722224
          Length = 2244

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2051 HSKISKHMT 2059
>XP_006722223
          Length = 2268

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            H K+SK +T
Sbjct: 2075 HSKISKHMT 2083
>XP_005257619
          Length = 320

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GKVSKTLT 9
           G +SKTLT
Sbjct: 227 GVISKTLT 234
>XP_006722070
          Length = 320

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GKVSKTLT 9
           G +SKTLT
Sbjct: 227 GVISKTLT 234
>XP_005257617
          Length = 320

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GKVSKTLT 9
           G +SKTLT
Sbjct: 227 GVISKTLT 234
>XP_005257618
          Length = 320

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GKVSKTLT 9
           G +SKTLT
Sbjct: 227 GVISKTLT 234
>XP_005257616
          Length = 320

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GKVSKTLT 9
           G +SKTLT
Sbjct: 227 GVISKTLT 234
>XP_005265259
          Length = 379

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   HGKVSKTLT 9
           HG V +TLT
Sbjct: 290 HGYVHETLT 298
>NP_001273700
          Length = 2490

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            HGK + T+T
Sbjct: 1442 HGKRNNTIT 1450
>NP_115593
          Length = 2603

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            HGK + T+T
Sbjct: 1555 HGKRNNTIT 1563
>NP_942592
          Length = 2352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            HGK + T+T
Sbjct: 1304 HGKRNNTIT 1312
>XP_005265728
          Length = 2351

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            HGK + T+T
Sbjct: 1303 HGKRNNTIT 1311
>XP_005265724
          Length = 2602

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            HGK + T+T
Sbjct: 1554 HGKRNNTIT 1562
>NP_001269796
          Length = 251

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GKVSKT 7
           GK+SKT
Sbjct: 97  GKISKT 102
>NP_001269800
          Length = 493

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GKVSKT 7
           GK+SKT
Sbjct: 263 GKISKT 268
>NP_001269801
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GKVSKT 7
           GK+SKT
Sbjct: 263 GKISKT 268
>NP_001269799
          Length = 463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GKVSKT 7
           GK+SKT
Sbjct: 263 GKISKT 268
>NP_001121163
          Length = 321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GKVSKT 7
           GK+SKT
Sbjct: 263 GKISKT 268
>NP_057208
          Length = 417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GKVSKT 7
           GK+SKT
Sbjct: 263 GKISKT 268
>NP_001269797
          Length = 378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GKVSKT 7
           GK+SKT
Sbjct: 263 GKISKT 268
>NP_001269798
          Length = 396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GKVSKT 7
           GK+SKT
Sbjct: 263 GKISKT 268
>NP_060695
          Length = 513

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GKVSKTLT 9
           GK+ +TLT
Sbjct: 474 GKLERTLT 481
>NP_056083
          Length = 2243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            HG+  +TLT
Sbjct: 2020 HGETLETLT 2028
>XP_005251560
          Length = 462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GKVSKTLT 9
           GK+ +TLT
Sbjct: 423 GKLERTLT 430
>XP_005247302
          Length = 2248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    HGKVSKTLT 9
            HG+  +TLT
Sbjct: 2025 HGETLETLT 2033
>NP_899234
          Length = 1134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GKVSKT 7
           GK+SKT
Sbjct: 179 GKISKT 184
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.306    0.120    0.325 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 429,925
Number of extensions: 614
Number of successful extensions: 75
Number of sequences better than 10000.0: 75
Number of HSP's gapped: 75
Number of HSP's successfully gapped: 75
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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