Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001257436                                                           21     229
NP_001257437                                                           21     229
NP_006281                                                              21     229
XP_006715618                                                           21     229
XP_005267176                                                           21     229
NP_063945                                                              17    2528
XP_006717250                                                           17    2528
NP_001157951                                                           16    5631
NP_443076                                                              16    5631
NP_690051                                                              16    5631
NP_006038                                                              16    5631
NP_001185769                                                           16    5631
NP_001185767                                                           16    5631
NP_078945                                                              16    5631
XP_005250515                                                           16    5631
XP_005250514                                                           16    5631
XP_006714754                                                           16    5631
XP_005248656                                                           16    5631
NP_061877                                                              16    5631
NP_001186732                                                           16    7355
NP_077298                                                              16    7355
NP_015628                                                              16    7355
NP_115570                                                              16    7355
NP_001276040                                                           16    7355
XP_005257785                                                           16    7355
XP_006712165                                                           16    7355
NP_000279                                                              15    9605
NP_079535                                                              15    9605
NP_751898                                                              15    9605
NP_002432                                                              15    9605
NP_751897                                                              15    9605
NP_001257449                                                           15    9605
NP_777612                                                              15    9605
NP_055807                                                              15    9605
NP_003986                                                              15    9605
NP_005384                                                              15    9605
NP_054825                                                              15    9605
NP_001092275                                                           15    9605
NP_001012421                                                           15    9605
NP_001005739                                                           15    9605
NP_001156729                                                           15    9605
NP_001243549                                                           15    9605
NP_057600                                                              15    9605
NP_001012419                                                           15    9605
XP_006725221                                                           15    9605
XP_006723739                                                           15    9605
XP_005267488                                                           15    9605
XP_005267487                                                           15    9605
XP_006717832                                                           15    9605
XP_006717831                                                           15    9605
XP_005272582                                                           15    9605
XP_006716841                                                           15    9605
XP_005251535                                                           15    9605
XP_005272576                                                           15    9605
XP_005267076                                                           15    9605
XP_006712092                                                           15    9605
XP_006710328                                                           15    9605
NP_612478                                                              15    9605
NP_055287                                                              15    9605
NP_001243548                                                           15    9605
>NP_001257436
          Length = 790

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   HFASASGKV 9
           HFA+ASGKV
Sbjct: 636 HFAAASGKV 644
>NP_001257437
          Length = 790

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   HFASASGKV 9
           HFA+ASGKV
Sbjct: 636 HFAAASGKV 644
>NP_006281
          Length = 790

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   HFASASGKV 9
           HFA+ASGKV
Sbjct: 636 HFAAASGKV 644
>XP_006715618
          Length = 577

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   HFASASGKV 9
           HFA+ASGKV
Sbjct: 423 HFAAASGKV 431
>XP_005267176
          Length = 790

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   HFASASGKV 9
           HFA+ASGKV
Sbjct: 636 HFAAASGKV 644
>NP_063945
          Length = 644

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   HFASASGKV 9
           HF S  GKV
Sbjct: 424 HFTSGDGKV 432
>XP_006717250
          Length = 610

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   HFASASGKV 9
           HF S  GKV
Sbjct: 390 HFTSGDGKV 398
>NP_001157951
          Length = 138

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  HFASASGK 8
          H AS SGK
Sbjct: 81 HMASQSGK 88
>NP_443076
          Length = 536

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FASASGK 8
           FA+ASGK
Sbjct: 451 FAAASGK 457
>NP_690051
          Length = 932

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FASASGK 8
           FAS+SGK
Sbjct: 846 FASSSGK 852
>NP_006038
          Length = 932

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FASASGK 8
           FAS+SGK
Sbjct: 846 FASSSGK 852
>NP_001185769
          Length = 932

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FASASGK 8
           FAS+SGK
Sbjct: 846 FASSSGK 852
>NP_001185767
          Length = 932

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FASASGK 8
           FAS+SGK
Sbjct: 846 FASSSGK 852
>NP_078945
          Length = 614

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   HFASASGK 8
           H+A+A+GK
Sbjct: 270 HWAAAAGK 277
>XP_005250515
          Length = 1083

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HFASASG 7
           H+A+ASG
Sbjct: 150 HYAAASG 156
>XP_005250514
          Length = 1089

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HFASASG 7
           H+A+ASG
Sbjct: 150 HYAAASG 156
>XP_006714754
          Length = 452

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   HFASASGK 8
           H+A+A+GK
Sbjct: 108 HWAAAAGK 115
>XP_005248656
          Length = 491

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   HFASASGK 8
           H+A+A+GK
Sbjct: 147 HWAAAAGK 154
>NP_061877
          Length = 1089

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   HFASASG 7
           H+A+ASG
Sbjct: 150 HYAAASG 156
>NP_001186732
          Length = 294

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HFASASGKV 9
           HF   SGK+
Sbjct: 103 HFTGLSGKL 111
>NP_077298
          Length = 300

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HFASASGKV 9
           HF   SGK+
Sbjct: 109 HFTGLSGKL 117
>NP_015628
          Length = 1119

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   HFASASGKV 9
           HFA++ G++
Sbjct: 451 HFAASYGRI 459
>NP_115570
          Length = 306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   HFASASGKV 9
           HF + +GK+
Sbjct: 185 HFTALNGKI 193
>NP_001276040
          Length = 243

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   HFASASGKV 9
           HF + +GK+
Sbjct: 122 HFTALNGKI 130
>XP_005257785
          Length = 1887

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   HFASASG 7
           HF+ ASG
Sbjct: 133 HFSQASG 139
>XP_006712165
          Length = 300

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   HFASASGKV 9
           HF   SGK+
Sbjct: 109 HFTGLSGKL 117
>NP_000279
          Length = 323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FASASG 7
           FASASG
Sbjct: 171 FASASG 176
>NP_079535
          Length = 822

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   HFASASGKV 9
           H AS  GKV
Sbjct: 390 HIASLIGKV 398
>NP_751898
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   HFASASGKV 9
           H AS  GKV
Sbjct: 373 HIASLIGKV 381
>NP_002432
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   HFASASGKV 9
           H AS  GKV
Sbjct: 373 HIASLIGKV 381
>NP_751897
          Length = 835

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   HFASASGKV 9
           H AS  GKV
Sbjct: 373 HIASLIGKV 381
>NP_001257449
          Length = 1068

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   HFASASGKV 9
           HF   +GK+
Sbjct: 949 HFGEEAGKI 957
>NP_777612
          Length = 459

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   HFASASGK 8
           HF ++SG+
Sbjct: 142 HFGNSSGR 149
>NP_055807
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   HFASASGKV 9
           HF   +GK+
Sbjct: 959 HFGEEAGKI 967
>NP_003986
          Length = 1047

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   HFASASGKV 9
           HF  A+G++
Sbjct: 215 HFIRANGRI 223
>NP_005384
          Length = 1909

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    FASASG 7
            FASASG
Sbjct: 1133 FASASG 1138
>NP_054825
          Length = 691

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FASASGKV 9
           FA+ SGK+
Sbjct: 315 FAARSGKI 322
>NP_001092275
          Length = 823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  HFASASGKV 9
          H A ASG V
Sbjct: 72 HLACASGHV 80
>NP_001012421
          Length = 823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  HFASASGKV 9
          H A ASG V
Sbjct: 72 HLACASGHV 80
>NP_001005739
          Length = 965

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   HFASASGK 8
           HF +A GK
Sbjct: 175 HFNTAGGK 182
>NP_001156729
          Length = 1932

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    FASASG 7
            FASASG
Sbjct: 1156 FASASG 1161
>NP_001243549
          Length = 778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   HFASASGKV 9
           HF  ++GK+
Sbjct: 454 HFTESTGKL 462
>NP_057600
          Length = 977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   HFASASGK 8
           HF +A GK
Sbjct: 187 HFNTAGGK 194
>NP_001012419
          Length = 823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  HFASASGKV 9
          H A ASG V
Sbjct: 72 HLACASGHV 80
>XP_006725221
          Length = 165

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  HFASASGKV 9
          H A ASG V
Sbjct: 72 HLACASGHV 80
>XP_006723739
          Length = 165

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  HFASASGKV 9
          H A ASG V
Sbjct: 72 HLACASGHV 80
>XP_005267488
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   HFASASGKV 9
           HF   +GK+
Sbjct: 959 HFGEEAGKI 967
>XP_005267487
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   HFASASGKV 9
           HF   +GK+
Sbjct: 959 HFGEEAGKI 967
>XP_006717832
          Length = 778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   HFASASGKV 9
           HF  ++GK+
Sbjct: 454 HFTESTGKL 462
>XP_006717831
          Length = 778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   HFASASGKV 9
           HF  ++GK+
Sbjct: 454 HFTESTGKL 462
>XP_005272582
          Length = 822

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  HFASASGKV 9
          H A ASG V
Sbjct: 72 HLACASGHV 80
>XP_006716841
          Length = 1026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   HFASASGKV 9
           HF  A+G++
Sbjct: 215 HFIRANGRI 223
>XP_005251535
          Length = 1050

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   HFASASGKV 9
           HF  A+G++
Sbjct: 215 HFIRANGRI 223
>XP_005272576
          Length = 822

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  HFASASGKV 9
          H A ASG V
Sbjct: 72 HLACASGHV 80
>XP_005267076
          Length = 285

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FASASG 7
           FASASG
Sbjct: 133 FASASG 138
>XP_006712092
          Length = 941

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   HFASASGK 8
           HF +A GK
Sbjct: 187 HFNTAGGK 194
>XP_006710328
          Length = 165

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  HFASASGKV 9
          H A ASG V
Sbjct: 72 HLACASGHV 80
>NP_612478
          Length = 778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   HFASASGKV 9
           HF  ++GK+
Sbjct: 454 HFTESTGKL 462
>NP_055287
          Length = 778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   HFASASGKV 9
           HF  ++GK+
Sbjct: 454 HFTESTGKL 462
>NP_001243548
          Length = 792

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   HFASASGKV 9
           HF  ++GK+
Sbjct: 454 HFTESTGKL 462
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.120    0.337 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 513,174
Number of extensions: 1064
Number of successful extensions: 60
Number of sequences better than 10000.0: 60
Number of HSP's gapped: 60
Number of HSP's successfully gapped: 60
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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