Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              20     299
NP_079039                                                              18    1482
NP_996897                                                              18    1482
XP_005271269                                                           18    1482
NP_001159395                                                           17    3301
NP_000536                                                              17    3301
NP_000449                                                              17    3301
NP_005057                                                              17    3301
NP_001873                                                              17    3301
XP_005253988                                                           17    3301
XP_005271173                                                           17    3301
XP_005271172                                                           17    3301
XP_005271170                                                           17    3301
XP_005271169                                                           17    3301
XP_005271168                                                           17    3301
NP_510966                                                              17    4312
NP_001775                                                              17    4312
NP_001020331                                                           17    4312
XP_005260229                                                           17    4312
XP_005260228                                                           17    4312
XP_005260227                                                           17    4312
NP_004470                                                              16    5631
NP_001015508                                                           16    5631
NP_005550                                                              16    5631
XP_005273541                                                           16    5631
XP_005273540                                                           16    5631
NP_037489                                                              16    5631
NP_060661                                                              16    7355
NP_008832                                                              16    7355
NP_001129198                                                           16    7355
NP_055309                                                              16    7355
NP_078843                                                              16    7355
XP_006721103                                                           16    7355
XP_005255314                                                           16    7355
XP_006721102                                                           16    7355
XP_005255313                                                           16    7355
XP_005255312                                                           16    7355
XP_006721101                                                           16    7355
XP_005255311                                                           16    7355
XP_005255310                                                           16    7355
XP_005254461                                                           16    7355
XP_006720603                                                           16    7355
XP_006720602                                                           16    7355
XP_005266498                                                           16    7355
XP_006716461                                                           16    7355
XP_005273698                                                           16    7355
XP_005273697                                                           16    7355
XP_005273696                                                           16    7355
XP_005273695                                                           16    7355
XP_005273694                                                           16    7355
XP_005273693                                                           16    7355
XP_005273692                                                           16    7355
XP_006716460                                                           16    7355
XP_006716459                                                           16    7355
NP_002290                                                              15    9605
NP_065801                                                              15    9605
NP_056332                                                              15    9605
NP_945322                                                              15    9605
XP_005274495                                                           15    9605
XP_006718877                                                           15    9605
XP_006718876                                                           15    9605
XP_006715638                                                           15    9605
XP_005267216                                                           15    9605
NP_115521                                                              15    9605
>NP_115803
          Length = 1156

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    GTGLNQSR 8
            GTGLNQSR
Sbjct: 1066 GTGLNQSR 1073
>NP_079039
          Length = 848

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  TGLNQSRM 9
          TG NQSRM
Sbjct: 82 TGANQSRM 89
>NP_996897
          Length = 545

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  TGLNQSRM 9
          TG NQSRM
Sbjct: 82 TGANQSRM 89
>XP_005271269
          Length = 783

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  TGLNQSRM 9
          TG NQSRM
Sbjct: 82 TGANQSRM 89
>NP_001159395
          Length = 531

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TGLNQSRM 9
           TGLNQS +
Sbjct: 143 TGLNQSHL 150
>NP_000536
          Length = 631

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TGLNQSRM 9
           TGLNQS +
Sbjct: 137 TGLNQSHL 144
>NP_000449
          Length = 557

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TGLNQSRM 9
           TGLNQS +
Sbjct: 143 TGLNQSHL 150
>NP_005057
          Length = 707

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GTGLNQSR 8
          G GLNQ+R
Sbjct: 37 GMGLNQNR 44
>NP_001873
          Length = 322

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GTGLNQSRM 9
           GTGL+ S+M
Sbjct: 249 GTGLDPSKM 257
>XP_005253988
          Length = 662

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TGLNQSRM 9
           TGLNQS +
Sbjct: 137 TGLNQSHL 144
>XP_005271173
          Length = 669

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GTGLNQSR 8
          G GLNQ+R
Sbjct: 37 GMGLNQNR 44
>XP_005271172
          Length = 669

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GTGLNQSR 8
          G GLNQ+R
Sbjct: 37 GMGLNQNR 44
>XP_005271170
          Length = 707

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GTGLNQSR 8
          G GLNQ+R
Sbjct: 37 GMGLNQNR 44
>XP_005271169
          Length = 707

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GTGLNQSR 8
          G GLNQ+R
Sbjct: 37 GMGLNQNR 44
>XP_005271168
          Length = 707

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GTGLNQSR 8
          G GLNQ+R
Sbjct: 37 GMGLNQNR 44
>NP_510966
          Length = 835

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GTGLNQSR 8
           GTG NQ+R
Sbjct: 819 GTGHNQTR 826
>NP_001775
          Length = 742

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GTGLNQSR 8
           GTG NQ+R
Sbjct: 726 GTGHNQTR 733
>NP_001020331
          Length = 786

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GTGLNQSR 8
           GTG NQ+R
Sbjct: 770 GTGHNQTR 777
>XP_005260229
          Length = 801

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GTGLNQSR 8
           GTG NQ+R
Sbjct: 785 GTGHNQTR 792
>XP_005260228
          Length = 845

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GTGLNQSR 8
           GTG NQ+R
Sbjct: 829 GTGHNQTR 836
>XP_005260227
          Length = 894

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GTGLNQSR 8
           GTG NQ+R
Sbjct: 878 GTGHNQTR 885
>NP_004470
          Length = 342

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TGLNQSR 8
           TG+N+SR
Sbjct: 288 TGMNESR 294
>NP_001015508
          Length = 322

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  GTGLNQSRM 9
          G+GL++SR+
Sbjct: 22 GSGLSKSRL 30
>NP_005550
          Length = 3075

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    GTGLNQSRM 9
            G GL QSR+
Sbjct: 1327 GQGLQQSRI 1335
>XP_005273541
          Length = 322

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  GTGLNQSRM 9
          G+GL++SR+
Sbjct: 22 GSGLSKSRL 30
>XP_005273540
          Length = 347

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  GTGLNQSRM 9
          G+GL++SR+
Sbjct: 22 GSGLSKSRL 30
>NP_037489
          Length = 347

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  GTGLNQSRM 9
          G+GL++SR+
Sbjct: 22 GSGLSKSRL 30
>NP_060661
          Length = 531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  GTGLNQSRM 9
          GTG NQS +
Sbjct: 55 GTGDNQSTL 63
>NP_008832
          Length = 2548

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TGLNQSRM 9
           TG+ QSR+
Sbjct: 804 TGIRQSRL 811
>NP_001129198
          Length = 420

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TGLNQSRM 9
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>NP_055309
          Length = 1962

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GTGLNQSR 8
           GTG +QSR
Sbjct: 686 GTGESQSR 693
>NP_078843
          Length = 420

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TGLNQSRM 9
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>XP_006721103
          Length = 1597

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GTGLNQSR 8
           GTG +QSR
Sbjct: 654 GTGESQSR 661
>XP_005255314
          Length = 1709

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GTGLNQSR 8
           GTG +QSR
Sbjct: 433 GTGESQSR 440
>XP_006721102
          Length = 1820

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GTGLNQSR 8
           GTG +QSR
Sbjct: 544 GTGESQSR 551
>XP_005255313
          Length = 1822

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GTGLNQSR 8
           GTG +QSR
Sbjct: 654 GTGESQSR 661
>XP_005255312
          Length = 1871

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GTGLNQSR 8
           GTG +QSR
Sbjct: 654 GTGESQSR 661
>XP_006721101
          Length = 1907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GTGLNQSR 8
           GTG +QSR
Sbjct: 654 GTGESQSR 661
>XP_005255311
          Length = 1913

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GTGLNQSR 8
           GTG +QSR
Sbjct: 686 GTGESQSR 693
>XP_005255310
          Length = 1919

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GTGLNQSR 8
           GTG +QSR
Sbjct: 654 GTGESQSR 661
>XP_005254461
          Length = 2600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TGLNQSRM 9
           TG+ QSR+
Sbjct: 785 TGIRQSRL 792
>XP_006720603
          Length = 2619

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TGLNQSRM 9
           TG+ QSR+
Sbjct: 804 TGIRQSRL 811
>XP_006720602
          Length = 2619

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TGLNQSRM 9
           TG+ QSR+
Sbjct: 804 TGIRQSRL 811
>XP_005266498
          Length = 531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  GTGLNQSRM 9
          GTG NQS +
Sbjct: 55 GTGDNQSTL 63
>XP_006716461
          Length = 318

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TGLNQSRM 9
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>XP_005273698
          Length = 383

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TGLNQSRM 9
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>XP_005273697
          Length = 405

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TGLNQSRM 9
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>XP_005273696
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TGLNQSRM 9
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>XP_005273695
          Length = 418

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TGLNQSRM 9
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>XP_005273694
          Length = 419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TGLNQSRM 9
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>XP_005273693
          Length = 442

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TGLNQSRM 9
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>XP_005273692
          Length = 443

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TGLNQSRM 9
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>XP_006716460
          Length = 444

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TGLNQSRM 9
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>XP_006716459
          Length = 444

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TGLNQSRM 9
           TG++QSR+
Sbjct: 195 TGISQSRI 202
>NP_002290
          Length = 1927

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    GLNQSRM 9
            GLN+SR+
Sbjct: 1654 GLNKSRL 1660
>NP_065801
          Length = 1204

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   GLNQSRM 9
           GLN++RM
Sbjct: 715 GLNRARM 721
>NP_056332
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGLNQSRM 9
           GT LN+S +
Sbjct: 416 GTSLNESSL 424
>NP_945322
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGLNQSRM 9
           GT LN+S +
Sbjct: 416 GTSLNESSL 424
>XP_005274495
          Length = 257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  GTGLNQ 6
          GTGLN+
Sbjct: 9  GTGLNR 14
>XP_006718877
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGLNQSRM 9
           GT LN+S +
Sbjct: 169 GTSLNESSL 177
>XP_006718876
          Length = 311

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGLNQSRM 9
           GT LN+S +
Sbjct: 210 GTSLNESSL 218
>XP_006715638
          Length = 745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGLNQSRM 9
           G G++ SRM
Sbjct: 440 GRGISDSRM 448
>XP_005267216
          Length = 745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGLNQSRM 9
           G G++ SRM
Sbjct: 440 GRGISDSRM 448
>NP_115521
          Length = 745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GTGLNQSRM 9
           G G++ SRM
Sbjct: 440 GRGISDSRM 448
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.126    0.347 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 592,785
Number of extensions: 889
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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