Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004831                                                              17    3301
XP_006724854                                                           17    3301
XP_005262556                                                           17    3301
NP_060420                                                              17    4312
NP_001230271                                                           17    4312
NP_620137                                                              17    4312
NP_001139504                                                           17    4312
XP_005257549                                                           17    4312
NP_001243197                                                           16    5631
NP_001243196                                                           16    5631
NP_115967                                                              16    5631
NP_001257941                                                           16    5631
XP_006718107                                                           16    5631
XP_006718106                                                           16    5631
NP_001009899                                                           16    7355
NP_660337                                                              16    7355
NP_060733                                                              16    7355
NP_000698                                                              16    7355
XP_006720926                                                           16    7355
XP_006720925                                                           16    7355
XP_006720924                                                           16    7355
XP_006720923                                                           16    7355
XP_005255218                                                           16    7355
XP_005255217                                                           16    7355
XP_005247266                                                           16    7355
XP_005247265                                                           16    7355
XP_006713065                                                           16    7355
XP_005264953                                                           16    7355
XP_006713064                                                           16    7355
XP_006713063                                                           16    7355
XP_006713062                                                           16    7355
XP_006713061                                                           16    7355
XP_006713060                                                           16    7355
XP_006713059                                                           16    7355
XP_006713058                                                           16    7355
XP_006713057                                                           16    7355
XP_006712103                                                           16    7355
XP_006712102                                                           16    7355
NP_955379                                                              16    7355
NP_115495                                                              15    9605
NP_620126                                                              15    9605
>NP_004831
          Length = 776

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   SLSAANTT 9
           SLSAANT+
Sbjct: 124 SLSAANTS 131
>XP_006724854
          Length = 695

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2  SLSAANTT 9
          SLSAANT+
Sbjct: 43 SLSAANTS 50
>XP_005262556
          Length = 727

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   SLSAANTT 9
           SLSAANT+
Sbjct: 124 SLSAANTS 131
>NP_060420
          Length = 1142

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSLSAANTT 9
           G +SAA+TT
Sbjct: 105 GQISAADTT 113
>NP_001230271
          Length = 1030

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSLSAANTT 9
           G +SAA+TT
Sbjct: 105 GQISAADTT 113
>NP_620137
          Length = 810

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   SLSAANT 8
           SLSAANT
Sbjct: 517 SLSAANT 523
>NP_001139504
          Length = 777

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   SLSAANT 8
           SLSAANT
Sbjct: 484 SLSAANT 490
>XP_005257549
          Length = 579

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSLSAANTT 9
           G +SAA+TT
Sbjct: 105 GQISAADTT 113
>NP_001243197
          Length = 1026

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSLSAANTT 9
           GSL +AN+T
Sbjct: 248 GSLHSANST 256
>NP_001243196
          Length = 1320

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSLSAANTT 9
           GSL +AN+T
Sbjct: 542 GSLHSANST 550
>NP_115967
          Length = 1320

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSLSAANTT 9
           GSL +AN+T
Sbjct: 542 GSLHSANST 550
>NP_001257941
          Length = 259

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  GSLSAANTT 9
          GSL A NTT
Sbjct: 4  GSLLAYNTT 12
>XP_006718107
          Length = 1330

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSLSAANTT 9
           GSL +AN+T
Sbjct: 552 GSLHSANST 560
>XP_006718106
          Length = 1338

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSLSAANTT 9
           GSL +AN+T
Sbjct: 560 GSLHSANST 568
>NP_001009899
          Length = 2245

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SLSAANTT 9
           SLSA+N+T
Sbjct: 642 SLSASNST 649
>NP_660337
          Length = 1748

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  GSLSAAN 7
          GS+SAAN
Sbjct: 47 GSVSAAN 53
>NP_060733
          Length = 1435

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GSLSAANTT 9
           G+L A NTT
Sbjct: 991 GALIATNTT 999
>NP_000698
          Length = 424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  GSLSAANTT 9
          G+LSA N T
Sbjct: 15 GTLSAPNAT 23

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GSLSAANTT 9
           GSLS+ +TT
Sbjct: 370 GSLSSRHTT 378
>XP_006720926
          Length = 1383

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  GSLSAAN 7
          GS+SAAN
Sbjct: 47 GSVSAAN 53
>XP_006720925
          Length = 1674

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  GSLSAAN 7
          GS+SAAN
Sbjct: 47 GSVSAAN 53
>XP_006720924
          Length = 1679

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  GSLSAAN 7
          GS+SAAN
Sbjct: 47 GSVSAAN 53
>XP_006720923
          Length = 1738

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  GSLSAAN 7
          GS+SAAN
Sbjct: 47 GSVSAAN 53
>XP_005255218
          Length = 1750

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  GSLSAAN 7
          GS+SAAN
Sbjct: 47 GSVSAAN 53
>XP_005255217
          Length = 1751

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  GSLSAAN 7
          GS+SAAN
Sbjct: 47 GSVSAAN 53
>XP_005247266
          Length = 2189

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SLSAANTT 9
           SLSA+N+T
Sbjct: 586 SLSASNST 593
>XP_005247265
          Length = 2211

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SLSAANTT 9
           SLSA+N+T
Sbjct: 608 SLSASNST 615
>XP_006713065
          Length = 709

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GSLSAAN 7
           GSLS+AN
Sbjct: 355 GSLSSAN 361
>XP_005264953
          Length = 713

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GSLSAAN 7
           GSLS+AN
Sbjct: 355 GSLSSAN 361
>XP_006713064
          Length = 1115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GSLSAAN 7
           GSLS+AN
Sbjct: 355 GSLSSAN 361
>XP_006713063
          Length = 1125

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GSLSAAN 7
           GSLS+AN
Sbjct: 355 GSLSSAN 361
>XP_006713062
          Length = 1158

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GSLSAAN 7
           GSLS+AN
Sbjct: 355 GSLSSAN 361
>XP_006713061
          Length = 1162

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GSLSAAN 7
           GSLS+AN
Sbjct: 355 GSLSSAN 361
>XP_006713060
          Length = 1162

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GSLSAAN 7
           GSLS+AN
Sbjct: 355 GSLSSAN 361
>XP_006713059
          Length = 1172

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GSLSAAN 7
           GSLS+AN
Sbjct: 355 GSLSSAN 361
>XP_006713058
          Length = 1172

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GSLSAAN 7
           GSLS+AN
Sbjct: 355 GSLSSAN 361
>XP_006713057
          Length = 1172

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GSLSAAN 7
           GSLS+AN
Sbjct: 355 GSLSSAN 361
>XP_006712103
          Length = 1175

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GSLSAANTT 9
           G+L A NTT
Sbjct: 731 GALIATNTT 739
>XP_006712102
          Length = 1313

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GSLSAANTT 9
           G+L A NTT
Sbjct: 869 GALIATNTT 877
>NP_955379
          Length = 712

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GSLSAAN 7
           GSLS+AN
Sbjct: 355 GSLSSAN 361
>NP_115495
          Length = 6306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    GSLSAANTT 9
            GSL A N T
Sbjct: 2853 GSLGAINVT 2861
>NP_620126
          Length = 140

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SAANTT 9
           SAANTT
Sbjct: 112 SAANTT 117
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.287   0.0989    0.235 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 321,994
Number of extensions: 468
Number of successful extensions: 42
Number of sequences better than 10000.0: 41
Number of HSP's gapped: 42
Number of HSP's successfully gapped: 42
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

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