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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004295                                                              18    1135
NP_003310                                                              17    4312
NP_597676                                                              17    4312
NP_001243779                                                           17    4312
NP_596869                                                              17    4312
NP_689594                                                              17    4312
XP_005246888                                                           17    4312
XP_006712788                                                           17    4312
XP_006712787                                                           17    4312
XP_006712786                                                           17    4312
XP_006712319                                                           17    4312
XP_006711698                                                           17    4312
NP_001186073                                                           17    4312
NP_001254479                                                           17    4312
NP_597681                                                              17    4312
NP_001182192                                                           16    5631
NP_079171                                                              16    5631
XP_006718038                                                           16    5631
XP_005270222                                                           16    5631

>NP_004295
          Length = 1620

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GSKMALQRS 9
           GSKMALQ S
Sbjct: 432 GSKMALQSS 440



>NP_003310
          Length = 26926

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     GSKMALQRS 9
             G KMA+QR+
Sbjct: 12844 GIKMAMQRN 12852



>NP_597676
          Length = 27051

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     GSKMALQRS 9
             G KMA+QR+
Sbjct: 12969 GIKMAMQRN 12977



>NP_001243779
          Length = 34350

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     GSKMALQRS 9
             G KMA+QR+
Sbjct: 20268 GIKMAMQRN 20276



>NP_596869
          Length = 33423

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     GSKMALQRS 9
             G KMA+QR+
Sbjct: 19341 GIKMAMQRN 19349



>NP_689594
          Length = 3549

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    GSKMALQRS 9
            G KMA++RS
Sbjct: 2262 GLKMAMERS 2270



>XP_005246888
          Length = 22663

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    GSKMALQRS 9
            G KMA+QR+
Sbjct: 8581 GIKMAMQRN 8589



>XP_006712788
          Length = 24022

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    GSKMALQRS 9
            G KMA+QR+
Sbjct: 9940 GIKMAMQRN 9948



>XP_006712787
          Length = 33978

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     GSKMALQRS 9
             G KMA+QR+
Sbjct: 19896 GIKMAMQRN 19904



>XP_006712786
          Length = 35484

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     GSKMALQRS 9
             G KMA+QR+
Sbjct: 21402 GIKMAMQRN 21410



>XP_006712319
          Length = 3308

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    GSKMALQRS 9
            G KMA++RS
Sbjct: 2021 GLKMAMERS 2029



>XP_006711698
          Length = 846

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GSKMALQR 8
           GS++ALQR
Sbjct: 702 GSQLALQR 709



>NP_001186073
          Length = 3327

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    GSKMALQRS 9
            G KMA++RS
Sbjct: 2040 GLKMAMERS 2048



>NP_001254479
          Length = 35991

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     GSKMALQRS 9
             G KMA+QR+
Sbjct: 21909 GIKMAMQRN 21917



>NP_597681
          Length = 27118

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1     GSKMALQRS 9
             G KMA+QR+
Sbjct: 13036 GIKMAMQRN 13044



>NP_001182192
          Length = 1033

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   GSKMALQRS 9
           G K ALQRS
Sbjct: 456 GEKGALQRS 464



>NP_079171
          Length = 517

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   GSKMALQRS 9
           G K ALQRS
Sbjct: 456 GEKGALQRS 464



>XP_006718038
          Length = 537

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   GSKMALQRS 9
           G K ALQRS
Sbjct: 456 GEKGALQRS 464



>XP_005270222
          Length = 561

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   GSKMALQRS 9
           G K ALQRS
Sbjct: 456 GEKGALQRS 464



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.309    0.115    0.278 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 368,007
Number of extensions: 501
Number of successful extensions: 19
Number of sequences better than 10000.0: 19
Number of HSP's gapped: 19
Number of HSP's successfully gapped: 19
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)