Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

XP_003961004                                                           18    1935
XP_005276139                                                           18    1935
NP_001230891                                                           18    1935
NP_002115                                                              16    5631
NP_002112                                                              16    5631
NP_653252                                                              16    5631
XP_005251225                                                           16    5631
XP_006716483                                                           16    5631
XP_005251224                                                           16    5631
NP_001230894                                                           16    5631
NP_036440                                                              16    7355
NP_060868                                                              16    7355
NP_001243334                                                           16    7355
XP_006718544                                                           16    7355
XP_006718543                                                           16    7355
XP_006718542                                                           16    7355
XP_005265375                                                           16    7355
NP_006246                                                              15    9605
>XP_003961004
          Length = 293

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   GSFRAVTL 8
           G FRAVTL
Sbjct: 109 GEFRAVTL 116
>XP_005276139
          Length = 313

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   GSFRAVTL 8
           G FRAVTL
Sbjct: 109 GEFRAVTL 116
>NP_001230891
          Length = 261

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  GSFRAVTL 8
          G FRAVTL
Sbjct: 77 GEFRAVTL 84
>NP_002115
          Length = 266

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  GSFRAVT 7
          G FRAVT
Sbjct: 74 GEFRAVT 80
>NP_002112
          Length = 258

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  GSFRAVT 7
          G FRAVT
Sbjct: 72 GEFRAVT 78
>NP_653252
          Length = 1463

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    GSFRAVT 7
            G FRAVT
Sbjct: 1306 GQFRAVT 1312
>XP_005251225
          Length = 848

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GSFRAVT 7
           G FRAVT
Sbjct: 691 GQFRAVT 697
>XP_006716483
          Length = 1367

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    GSFRAVT 7
            G FRAVT
Sbjct: 1210 GQFRAVT 1216
>XP_005251224
          Length = 1439

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    GSFRAVT 7
            G FRAVT
Sbjct: 1282 GQFRAVT 1288
>NP_001230894
          Length = 266

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  GSFRAVT 7
          G FRAVT
Sbjct: 74 GEFRAVT 80
>NP_036440
          Length = 1162

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GSFRAVTLQ 9
           GS+  VTLQ
Sbjct: 796 GSYLTVTLQ 804
>NP_060868
          Length = 1091

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GSFRAVTL 8
           GSF+ +TL
Sbjct: 893 GSFKRITL 900
>NP_001243334
          Length = 723

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GSFRAVTLQ 9
           GS+  VTLQ
Sbjct: 357 GSYLTVTLQ 365
>XP_006718544
          Length = 1056

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GSFRAVTLQ 9
           GS+  VTLQ
Sbjct: 690 GSYLTVTLQ 698
>XP_006718543
          Length = 1067

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GSFRAVTLQ 9
           GS+  VTLQ
Sbjct: 701 GSYLTVTLQ 709
>XP_006718542
          Length = 1145

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GSFRAVTLQ 9
           GS+  VTLQ
Sbjct: 779 GSYLTVTLQ 787
>XP_005265375
          Length = 1085

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GSFRAVTL 8
           GSF+ +TL
Sbjct: 887 GSFKRITL 894
>NP_006246
          Length = 683

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GSFRAVTLQ 9
           GSF   TLQ
Sbjct: 138 GSFTEATLQ 146
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.134    0.361 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 309,744
Number of extensions: 473
Number of successful extensions: 18
Number of sequences better than 10000.0: 18
Number of HSP's gapped: 18
Number of HSP's successfully gapped: 18
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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