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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              19     665
XP_005262424                                                           19     665
NP_060959                                                              17    2528
XP_005245394                                                           17    2528
XP_005245393                                                           17    2528
XP_006711515                                                           17    2528
XP_006711514                                                           17    2528
XP_006711513                                                           17    2528
NP_001132960                                                           17    3301
NP_056191                                                              17    3301
NP_733772                                                              17    3301
XP_005264304                                                           17    3301
XP_005264303                                                           17    3301
NP_001548                                                              17    4312
NP_001161770                                                           17    4312
NP_006124                                                              17    4312
XP_005274287                                                           17    4312
XP_005246588                                                           17    4312
XP_005246587                                                           17    4312
NP_001398                                                              16    7355
NP_000625                                                              16    7355
NP_055081                                                              16    7355
NP_001007470                                                           16    7355
NP_787954                                                              15    9605
NP_059130                                                              15    9605
NP_001138426                                                           15    9605
NP_001406                                                              15    9605
XP_005254520                                                           15    9605
XP_006714883                                                           15    9605
XP_006714882                                                           15    9605

>NP_722576
          Length = 3080

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GLVSKDAMA 9
            GLVSKD MA
Sbjct: 1928 GLVSKDVMA 1936



>XP_005262424
          Length = 2875

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GLVSKDAMA 9
            GLVSKD MA
Sbjct: 1723 GLVSKDVMA 1731



>NP_060959
          Length = 2964

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GLVSKDAM 8
           GL+SKDA+
Sbjct: 415 GLISKDAI 422




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GLVSKD 6
           GLVSKD
Sbjct: 247 GLVSKD 252




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GLVSKDAM 8
           GLV+KD++
Sbjct: 298 GLVNKDSV 305



>XP_005245394
          Length = 1741

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GLVSKDAM 8
           GL+SKDA+
Sbjct: 415 GLISKDAI 422




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GLVSKD 6
           GLVSKD
Sbjct: 247 GLVSKD 252




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GLVSKDAM 8
           GLV+KD++
Sbjct: 298 GLVNKDSV 305



>XP_005245393
          Length = 2663

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GLVSKDAM 8
           GL+SKDA+
Sbjct: 415 GLISKDAI 422




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GLVSKD 6
           GLVSKD
Sbjct: 247 GLVSKD 252




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GLVSKDAM 8
           GLV+KD++
Sbjct: 298 GLVNKDSV 305



>XP_006711515
          Length = 2904

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GLVSKDAM 8
           GL+SKDA+
Sbjct: 415 GLISKDAI 422




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GLVSKD 6
           GLVSKD
Sbjct: 247 GLVSKD 252




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GLVSKDAM 8
           GLV+KD++
Sbjct: 298 GLVNKDSV 305



>XP_006711514
          Length = 2964

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GLVSKDAM 8
           GL+SKDA+
Sbjct: 415 GLISKDAI 422




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GLVSKD 6
           GLVSKD
Sbjct: 247 GLVSKD 252




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GLVSKDAM 8
           GLV+KD++
Sbjct: 298 GLVNKDSV 305



>XP_006711513
          Length = 2964

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GLVSKDAM 8
           GL+SKDA+
Sbjct: 415 GLISKDAI 422




 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GLVSKD 6
           GLVSKD
Sbjct: 247 GLVSKD 252




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GLVSKDAM 8
           GLV+KD++
Sbjct: 298 GLVNKDSV 305



>NP_001132960
          Length = 690

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLVSKDAM 8
           GL+SKD M
Sbjct: 467 GLISKDEM 474



>NP_056191
          Length = 689

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLVSKDAM 8
           GL+SKD M
Sbjct: 466 GLISKDEM 473



>NP_733772
          Length = 690

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLVSKDAM 8
           GL+SKD M
Sbjct: 467 GLISKDEM 474



>XP_005264304
          Length = 569

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLVSKDAM 8
           GL+SKD M
Sbjct: 467 GLISKDEM 474



>XP_005264303
          Length = 689

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLVSKDAM 8
           GL+SKD M
Sbjct: 466 GLISKDEM 473



>NP_001548
          Length = 360

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GLVSKDAM 8
           GL+SKD++
Sbjct: 333 GLISKDSL 340



>NP_001161770
          Length = 360

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GLVSKDAM 8
           GL+SKD++
Sbjct: 333 GLISKDSL 340



>NP_006124
          Length = 1042

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GLVSKDAM 8
           GL+S+DAM
Sbjct: 502 GLLSEDAM 509



>XP_005274287
          Length = 1042

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GLVSKDAM 8
           GL+S+DAM
Sbjct: 502 GLLSEDAM 509



>XP_005246588
          Length = 360

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GLVSKDAM 8
           GL+SKD++
Sbjct: 333 GLISKDSL 340



>XP_005246587
          Length = 360

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GLVSKDAM 8
           GL+SKD++
Sbjct: 333 GLISKDSL 340



>NP_001398
          Length = 3312

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GLVSKDA 7
           GLVS+DA
Sbjct: 968 GLVSEDA 974



>NP_000625
          Length = 350

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GLVSKDAMA 9
           GLVSK+ +A
Sbjct: 324 GLVSKEFLA 332



>NP_055081
          Length = 93

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  GLVSKDAMA 9
          GLV+ DA+A
Sbjct: 52 GLVAADAVA 60



>NP_001007470
          Length = 92

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  GLVSKDAMA 9
          GLV+ DA+A
Sbjct: 52 GLVAADAVA 60



>NP_787954
          Length = 1551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   GLVSKD 6
           GL+SKD
Sbjct: 869 GLISKD 874



>NP_059130
          Length = 1551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   GLVSKD 6
           GL+SKD
Sbjct: 869 GLISKD 874



>NP_001138426
          Length = 176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   GLVSKDA 7
           GL+ KDA
Sbjct: 109 GLIQKDA 115



>NP_001406
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GLVSKDA 7
           G+VSKD+
Sbjct: 299 GIVSKDS 305



>XP_005254520
          Length = 1235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   GLVSKD 6
           GL+SKD
Sbjct: 553 GLISKD 558



>XP_006714883
          Length = 176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   GLVSKDA 7
           GL+ KDA
Sbjct: 109 GLIQKDA 115



>XP_006714882
          Length = 176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   GLVSKDA 7
           GL+ KDA
Sbjct: 109 GLIQKDA 115



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.124    0.311 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 429,681
Number of extensions: 583
Number of successful extensions: 42
Number of sequences better than 10000.0: 30
Number of HSP's gapped: 42
Number of HSP's successfully gapped: 42
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)