Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_680545                                                              17    4312
NP_680544                                                              17    4312
XP_005264090                                                           17    4312
NP_060388                                                              16    5631
NP_001091997                                                           16    5631
XP_006714309                                                           16    5631
NP_001012991                                                           16    5631
NP_004706                                                              16    7355
NP_430255                                                              16    7355
NP_114408                                                              16    7355
NP_001152758                                                           16    7355
NP_061759                                                              16    7355
XP_005266839                                                           16    7355
NP_000537                                                              15    9605
NP_001263689                                                           15    9605
NP_001119584                                                           15    9605
NP_001119586                                                           15    9605
NP_001263625                                                           15    9605
NP_001119590                                                           15    9605
NP_001263690                                                           15    9605
NP_001119585                                                           15    9605
NP_001263624                                                           15    9605
NP_001119588                                                           15    9605
NP_001119587                                                           15    9605
NP_001108451                                                           15    9605
NP_001108454                                                           15    9605
NP_001119589                                                           15    9605
NP_003713                                                              15    9605
NP_001108450                                                           15    9605
NP_001108452                                                           15    9605
NP_001108453                                                           15    9605
NP_001191121                                                           15    9605
NP_001119713                                                           15    9605
NP_001191117                                                           15    9605
NP_001119712                                                           15    9605
NP_001119714                                                           15    9605
NP_005418                                                              15    9605
NP_001191116                                                           15    9605
NP_001191115                                                           15    9605
NP_001191119                                                           15    9605
NP_001263627                                                           15    9605
NP_001191113                                                           15    9605
NP_001263628                                                           15    9605
NP_001191118                                                           15    9605
NP_001191120                                                           15    9605
NP_001191114                                                           15    9605
NP_001263626                                                           15    9605
XP_005247903                                                           15    9605
XP_005247901                                                           15    9605
XP_005247900                                                           15    9605
>NP_680545
          Length = 163

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  GLALIRVEG 9
          GLAL R+EG
Sbjct: 41 GLALGRLEG 49
>NP_680544
          Length = 163

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  GLALIRVEG 9
          GLAL R+EG
Sbjct: 41 GLALGRLEG 49
>XP_005264090
          Length = 473

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  GLALIRVEG 9
          GLAL R EG
Sbjct: 7  GLALERAEG 15
>NP_060388
          Length = 336

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GLALIRVEG 9
           GLAL+ ++G
Sbjct: 224 GLALLSIQG 232
>NP_001091997
          Length = 378

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  LALIRVEG 9
          L+LIR+EG
Sbjct: 39 LSLIRLEG 46
>XP_006714309
          Length = 307

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GLALIRVEG 9
           GLAL+ ++G
Sbjct: 195 GLALLSIQG 203
>NP_001012991
          Length = 97

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  GLALIRVEG 9
          GLAL+R  G
Sbjct: 10 GLALLRAAG 18
>NP_004706
          Length = 961

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GLALIRVEG 9
           G  L+R+EG
Sbjct: 105 GAVLVRLEG 113
>NP_430255
          Length = 867

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GLALIRVEG 9
           G  L+R+EG
Sbjct: 105 GAVLVRLEG 113
>NP_114408
          Length = 669

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GLALIRVEG 9
           GLAL+R  G
Sbjct: 125 GLALVRPPG 133
>NP_001152758
          Length = 649

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GLALIRVEG 9
           GLAL+R  G
Sbjct: 125 GLALVRPPG 133
>NP_061759
          Length = 798

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GLALIRVE 8
           G AL+R+E
Sbjct: 226 GTALVRIE 233
>XP_005266839
          Length = 867

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GLALIRVEG 9
           G  L+R+EG
Sbjct: 105 GAVLVRLEG 113
>NP_000537
          Length = 393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 194 LIRVEG 199
>NP_001263689
          Length = 354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 155 LIRVEG 160
>NP_001119584
          Length = 393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 194 LIRVEG 199
>NP_001119586
          Length = 341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 194 LIRVEG 199
>NP_001263625
          Length = 302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 155 LIRVEG 160
>NP_001119590
          Length = 354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 155 LIRVEG 160
>NP_001263690
          Length = 354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 155 LIRVEG 160
>NP_001119585
          Length = 346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 194 LIRVEG 199
>NP_001263624
          Length = 307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 155 LIRVEG 160
>NP_001119588
          Length = 209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  LIRVEG 9
          LIRVEG
Sbjct: 62 LIRVEG 67
>NP_001119587
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  LIRVEG 9
          LIRVEG
Sbjct: 62 LIRVEG 67
>NP_001108451
          Length = 487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 264 LIRVEG 269
>NP_001108454
          Length = 393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 170 LIRVEG 175
>NP_001119589
          Length = 214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  LIRVEG 9
          LIRVEG
Sbjct: 62 LIRVEG 67
>NP_003713
          Length = 680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 264 LIRVEG 269
>NP_001108450
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 264 LIRVEG 269
>NP_001108452
          Length = 586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 170 LIRVEG 175
>NP_001108453
          Length = 461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 170 LIRVEG 175
>NP_001191121
          Length = 565

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 143 LIRVEG 148
>NP_001119713
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 165 LIRVEG 170
>NP_001191117
          Length = 540

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 214 LIRVEG 219
>NP_001119712
          Length = 587

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 165 LIRVEG 170
>NP_001119714
          Length = 426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 165 LIRVEG 170
>NP_005418
          Length = 636

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 214 LIRVEG 219
>NP_001191116
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 214 LIRVEG 219
>NP_001191115
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 214 LIRVEG 219
>NP_001191119
          Length = 506

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 165 LIRVEG 170
>NP_001263627
          Length = 182

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  LIRVEG 9
          LIRVEG
Sbjct: 35 LIRVEG 40
>NP_001191113
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 214 LIRVEG 219
>NP_001263628
          Length = 187

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  LIRVEG 9
          LIRVEG
Sbjct: 35 LIRVEG 40
>NP_001191118
          Length = 354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 165 LIRVEG 170
>NP_001191120
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 165 LIRVEG 170
>NP_001191114
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 214 LIRVEG 219
>NP_001263626
          Length = 234

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  LIRVEG 9
          LIRVEG
Sbjct: 35 LIRVEG 40
>XP_005247903
          Length = 483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 264 LIRVEG 269
>XP_005247901
          Length = 663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 247 LIRVEG 252
>XP_005247900
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LIRVEG 9
           LIRVEG
Sbjct: 264 LIRVEG 269
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.154    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 383,972
Number of extensions: 581
Number of successful extensions: 50
Number of sequences better than 10000.0: 50
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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