Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005219                                                              19     665
NP_036221                                                              17    4312
NP_078966                                                              16    5631
XP_006723004                                                           16    5631
NP_003730                                                              16    7355
NP_001240837                                                           16    7355
NP_995317                                                              16    7355
NP_001345                                                              16    7355
NP_055855                                                              16    7355
NP_001809                                                              16    7355
NP_004769                                                              16    7355
NP_004568                                                              16    7355
NP_001094891                                                           16    7355
XP_006715824                                                           16    7355
XP_005271834                                                           16    7355
XP_005271833                                                           16    7355
XP_005271832                                                           16    7355
XP_005271831                                                           16    7355
XP_006715823                                                           16    7355
XP_005271830                                                           16    7355
XP_006712425                                                           16    7355
XP_006712424                                                           16    7355
NP_001344                                                              16    7355
NP_000206                                                              15    9605
NP_783163                                                              15    9605
NP_055099                                                              15    9605
NP_001092284                                                           15    9605
NP_001268366                                                           15    9605
NP_001014839                                                           15    9605
NP_775922                                                              15    9605
NP_001013663                                                           15    9605
NP_001268367                                                           15    9605
NP_008933                                                              15    9605
NP_065073                                                              15    9605
XP_005276449                                                           15    9605
XP_005260314                                                           15    9605
XP_006722808                                                           15    9605
XP_005259953                                                           15    9605
XP_006715582                                                           15    9605
NP_061755                                                              15    9605
NP_001014841                                                           15    9605
>NP_005219
          Length = 1210

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GLAKLLGVE 9
           GLAKLLG E
Sbjct: 857 GLAKLLGAE 865
>NP_036221
          Length = 738

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  GLAKLLGV 8
          GLA+LLG+
Sbjct: 85 GLARLLGL 92
>NP_078966
          Length = 14507

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1     GLAKLLGV 8
             GLA LLGV
Sbjct: 14459 GLAGLLGV 14466
>XP_006723004
          Length = 6443

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GLAKLLGV 8
            GLA LLGV
Sbjct: 6395 GLAGLLGV 6402
>NP_003730
          Length = 323

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLAKLLGV 8
           GLAK +GV
Sbjct: 158 GLAKSIGV 165
>NP_001240837
          Length = 323

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLAKLLGV 8
           GLAK +GV
Sbjct: 158 GLAKSIGV 165
>NP_995317
          Length = 323

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLAKLLGV 8
           GLAK +GV
Sbjct: 158 GLAKSIGV 165
>NP_001345
          Length = 323

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLAKLLGV 8
           GLAK +GV
Sbjct: 158 GLAKSIGV 165
>NP_055855
          Length = 2098

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LAKLLGV 8
            LAK+LGV
Sbjct: 1910 LAKILGV 1916
>NP_001809
          Length = 323

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLAKLLGV 8
           GLAK +GV
Sbjct: 158 GLAKSIGV 165
>NP_004769
          Length = 395

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GLAKLLGV 8
          GLA LLG+
Sbjct: 40 GLASLLGL 47
>NP_004568
          Length = 225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LAKLLGVE 9
          LAK+ GVE
Sbjct: 34 LAKICGVE 41
>NP_001094891
          Length = 1022

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LAKLLGV 8
           +AKLLGV
Sbjct: 303 IAKLLGV 309
>XP_006715824
          Length = 180

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LAKLLGVE 9
          LAK+ GVE
Sbjct: 34 LAKICGVE 41
>XP_005271834
          Length = 225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LAKLLGVE 9
          LAK+ GVE
Sbjct: 34 LAKICGVE 41
>XP_005271833
          Length = 225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LAKLLGVE 9
          LAK+ GVE
Sbjct: 34 LAKICGVE 41
>XP_005271832
          Length = 225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LAKLLGVE 9
          LAK+ GVE
Sbjct: 34 LAKICGVE 41
>XP_005271831
          Length = 225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LAKLLGVE 9
          LAK+ GVE
Sbjct: 34 LAKICGVE 41
>XP_006715823
          Length = 225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LAKLLGVE 9
          LAK+ GVE
Sbjct: 34 LAKICGVE 41
>XP_005271830
          Length = 225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LAKLLGVE 9
          LAK+ GVE
Sbjct: 34 LAKICGVE 41
>XP_006712425
          Length = 1349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LAKLLGV 8
            LAK+LGV
Sbjct: 1161 LAKILGV 1167
>XP_006712424
          Length = 1376

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LAKLLGV 8
            LAK+LGV
Sbjct: 1188 LAKILGV 1194
>NP_001344
          Length = 323

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLAKLLGV 8
           GLAK +GV
Sbjct: 158 GLAKSIGV 165
>NP_000206
          Length = 1124

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GLAKLLGVE 9
           GLAKLL ++
Sbjct: 969 GLAKLLPLD 977
>NP_783163
          Length = 407

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GLAKLLG 7
           GLA LLG
Sbjct: 190 GLASLLG 196
>NP_055099
          Length = 729

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GLAKLLG 7
           GLA++LG
Sbjct: 264 GLARILG 270
>NP_001092284
          Length = 473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LAKLLGVE 9
           L KL+G+E
Sbjct: 170 LEKLIGIE 177
>NP_001268366
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GLAKLLG 7
           GLA LLG
Sbjct: 151 GLASLLG 157
>NP_001014839
          Length = 729

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GLAKLLG 7
           GLA++LG
Sbjct: 264 GLARILG 270
>NP_775922
          Length = 6996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    LAKLLGVE 9
            LAKL GV+
Sbjct: 1581 LAKLCGVD 1588
>NP_001013663
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLAKLLGV 8
           GLA LLG+
Sbjct: 158 GLATLLGL 165
>NP_001268367
          Length = 368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GLAKLLG 7
           GLA LLG
Sbjct: 151 GLASLLG 157
>NP_008933
          Length = 407

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GLAKLLG 7
           GLA LLG
Sbjct: 190 GLASLLG 196
>NP_065073
          Length = 2177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GLAKLLGVE 9
           GLA +LG E
Sbjct: 890 GLAFILGAE 898
>XP_005276449
          Length = 171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GLAKLLG 7
          GLA++LG
Sbjct: 60 GLARMLG 66
>XP_005260314
          Length = 407

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GLAKLLG 7
           GLA LLG
Sbjct: 190 GLASLLG 196
>XP_006722808
          Length = 1124

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GLAKLLGVE 9
           GLAKLL ++
Sbjct: 969 GLAKLLPLD 977
>XP_005259953
          Length = 1167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    GLAKLLGVE 9
            GLAKLL ++
Sbjct: 1012 GLAKLLPLD 1020
>XP_006715582
          Length = 2106

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GLAKLLGVE 9
           GLA +LG E
Sbjct: 819 GLAFILGAE 827
>NP_061755
          Length = 795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  LAKLLGVE 9
          LAK LG+E
Sbjct: 48 LAKTLGLE 55
>NP_001014841
          Length = 712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GLAKLLG 7
           GLA++LG
Sbjct: 247 GLARILG 253
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.147    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 442,723
Number of extensions: 911
Number of successful extensions: 41
Number of sequences better than 10000.0: 41
Number of HSP's gapped: 41
Number of HSP's successfully gapped: 41
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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