Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           20     509
NP_001185763                                                           20     509
NP_055459                                                              20     509
NP_001002811                                                           20     509
NP_001002812                                                           20     509
XP_006726410                                                           20     509
XP_006711719                                                           20     509
XP_006711717                                                           20     509
XP_006711716                                                           20     509
XP_006711715                                                           20     509
XP_006711714                                                           20     509
XP_006711713                                                           20     509
XP_006711712                                                           20     509
XP_006711711                                                           20     509
XP_006711710                                                           20     509
XP_006711709                                                           20     509
XP_005277503                                                           20     509
XP_005273038                                                           20     509
XP_006711708                                                           20     509
XP_005277500                                                           20     509
XP_006711707                                                           20     509
XP_005277499                                                           20     509
XP_006711706                                                           20     509
XP_006711705                                                           20     509
XP_006711164                                                           20     509
NP_000101                                                              17    3301
XP_006710460                                                           17    3301
XP_005270619                                                           17    3301
NP_001230111                                                           16    5631
NP_000044                                                              16    5631
NP_001005918                                                           16    5631
XP_005266488                                                           16    5631
XP_006719902                                                           16    5631
XP_006719901                                                           16    5631
XP_005266489                                                           16    5631
XP_005266487                                                           16    5631
XP_005266486                                                           16    5631
XP_005266485                                                           16    5631
XP_005266484                                                           16    5631
XP_006719900                                                           16    5631
XP_005266480                                                           16    5631
XP_005266481                                                           16    5631
NP_066008                                                              16    7355
NP_620165                                                              16    7355
NP_473455                                                              16    7355
NP_060647                                                              15    9605
NP_000258                                                              15    9605
NP_001035957                                                           15    9605
XP_006722792                                                           15    9605
XP_006722790                                                           15    9605
XP_006721990                                                           15    9605
XP_006721989                                                           15    9605
XP_005258041                                                           15    9605
XP_006721988                                                           15    9605
XP_006721987                                                           15    9605
XP_006721986                                                           15    9605
XP_005258040                                                           15    9605
XP_006721985                                                           15    9605
XP_006714086                                                           15    9605
XP_006714085                                                           15    9605
XP_006714084                                                           15    9605
NP_001129973                                                           15    9605
>NP_001185761
          Length = 2240

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 531 KTLEANEM 538
>NP_001185763
          Length = 2362

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 465 KTLEANEM 472
>NP_055459
          Length = 2346

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 465 KTLEANEM 472
>NP_001002811
          Length = 1132

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 628 KTLEANEM 635
>NP_001002812
          Length = 969

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 465 KTLEANEM 472
>XP_006726410
          Length = 2087

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 540 KTLEANEM 547
>XP_006711719
          Length = 2302

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 531 KTLEANEM 538
>XP_006711717
          Length = 2385

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 531 KTLEANEM 538
>XP_006711716
          Length = 2411

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 531 KTLEANEM 538
>XP_006711715
          Length = 2428

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 465 KTLEANEM 472
>XP_006711714
          Length = 2429

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 465 KTLEANEM 472
>XP_006711713
          Length = 2432

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 468 KTLEANEM 475
>XP_006711712
          Length = 2473

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 628 KTLEANEM 635
>XP_006711711
          Length = 2482

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 628 KTLEANEM 635
>XP_006711710
          Length = 2494

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 531 KTLEANEM 538
>XP_006711709
          Length = 2495

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 531 KTLEANEM 538
>XP_005277503
          Length = 2498

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 628 KTLEANEM 635
>XP_005273038
          Length = 2509

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 628 KTLEANEM 635
>XP_006711708
          Length = 2512

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 628 KTLEANEM 635
>XP_005277500
          Length = 2525

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 628 KTLEANEM 635
>XP_006711707
          Length = 2553

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 628 KTLEANEM 635
>XP_005277499
          Length = 2561

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 628 KTLEANEM 635
>XP_006711706
          Length = 2591

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 628 KTLEANEM 635
>XP_006711705
          Length = 2592

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 628 KTLEANEM 635
>XP_006711164
          Length = 2087

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   KTLEANEM 9
           KTLEANEM
Sbjct: 540 KTLEANEM 547
>NP_000101
          Length = 1025

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GKTLEANEM 9
           GK+L  NEM
Sbjct: 258 GKSLSVNEM 266
>XP_006710460
          Length = 889

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GKTLEANEM 9
           GK+L  NEM
Sbjct: 258 GKSLSVNEM 266
>XP_005270619
          Length = 953

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GKTLEANEM 9
           GK+L  NEM
Sbjct: 258 GKSLSVNEM 266
>NP_001230111
          Length = 1354

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GKTLEANEM 9
           GK LE N M
Sbjct: 732 GKVLEGNTM 740
>NP_000044
          Length = 1465

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GKTLEANEM 9
           GK LE N M
Sbjct: 843 GKVLEGNTM 851
>NP_001005918
          Length = 1258

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GKTLEANEM 9
           GK LE N M
Sbjct: 681 GKVLEGNTM 689
>XP_005266488
          Length = 1453

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GKTLEANEM 9
           GK LE N M
Sbjct: 831 GKVLEGNTM 839
>XP_006719902
          Length = 676

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GKTLEANEM 9
           GK LE N M
Sbjct: 115 GKVLEGNTM 123
>XP_006719901
          Length = 737

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GKTLEANEM 9
           GK LE N M
Sbjct: 115 GKVLEGNTM 123
>XP_005266489
          Length = 1303

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GKTLEANEM 9
           GK LE N M
Sbjct: 681 GKVLEGNTM 689
>XP_005266487
          Length = 1465

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GKTLEANEM 9
           GK LE N M
Sbjct: 843 GKVLEGNTM 851
>XP_005266486
          Length = 1355

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GKTLEANEM 9
           GK LE N M
Sbjct: 843 GKVLEGNTM 851
>XP_005266485
          Length = 1381

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GKTLEANEM 9
           GK LE N M
Sbjct: 759 GKVLEGNTM 767
>XP_005266484
          Length = 1387

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GKTLEANEM 9
           GK LE N M
Sbjct: 765 GKVLEGNTM 773
>XP_006719900
          Length = 1433

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GKTLEANEM 9
           GK LE N M
Sbjct: 811 GKVLEGNTM 819
>XP_005266480
          Length = 1433

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GKTLEANEM 9
           GK LE N M
Sbjct: 811 GKVLEGNTM 819
>XP_005266481
          Length = 1433

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GKTLEANEM 9
           GK LE N M
Sbjct: 811 GKVLEGNTM 819
>NP_066008
          Length = 776

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   KTLEANEM 9
           KTLE N M
Sbjct: 290 KTLEVNPM 297
>NP_620165
          Length = 266

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  KTLEANEM 9
          KTL AN M
Sbjct: 11 KTLNANNM 18
>NP_473455
          Length = 731

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  KTLEANEM 9
          KTL AN M
Sbjct: 11 KTLNANNM 18
>NP_060647
          Length = 1770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KTLEANEM 9
            KTL A+EM
Sbjct: 1470 KTLTASEM 1477
>NP_000258
          Length = 2818

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KTLEANE 8
            KTL ANE
Sbjct: 1892 KTLAANE 1898
>NP_001035957
          Length = 2839

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KTLEANE 8
            KTL ANE
Sbjct: 1913 KTLAANE 1919
>XP_006722792
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GKTLEANEM 9
           G TLE N M
Sbjct: 283 GLTLERNRM 291
>XP_006722790
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GKTLEANEM 9
           G TLE N M
Sbjct: 440 GLTLERNRM 448
>XP_006721990
          Length = 2823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KTLEANE 8
            KTL ANE
Sbjct: 1923 KTLAANE 1929
>XP_006721989
          Length = 2823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KTLEANE 8
            KTL ANE
Sbjct: 1923 KTLAANE 1929
>XP_005258041
          Length = 2836

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KTLEANE 8
            KTL ANE
Sbjct: 1892 KTLAANE 1898
>XP_006721988
          Length = 2846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KTLEANE 8
            KTL ANE
Sbjct: 1902 KTLAANE 1908
>XP_006721987
          Length = 2849

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KTLEANE 8
            KTL ANE
Sbjct: 1923 KTLAANE 1929
>XP_006721986
          Length = 2854

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KTLEANE 8
            KTL ANE
Sbjct: 1910 KTLAANE 1916
>XP_005258040
          Length = 2857

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KTLEANE 8
            KTL ANE
Sbjct: 1913 KTLAANE 1919
>XP_006721985
          Length = 2867

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    KTLEANE 8
            KTL ANE
Sbjct: 1923 KTLAANE 1929
>XP_006714086
          Length = 1690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KTLEANEM 9
            KTL A+EM
Sbjct: 1390 KTLTASEM 1397
>XP_006714085
          Length = 1690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KTLEANEM 9
            KTL A+EM
Sbjct: 1390 KTLTASEM 1397
>XP_006714084
          Length = 1753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KTLEANEM 9
            KTL A+EM
Sbjct: 1470 KTLTASEM 1477
>NP_001129973
          Length = 666

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GKTLEANEM 9
           G TLE N M
Sbjct: 440 GLTLERNRM 448
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.296    0.116    0.289 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 407,443
Number of extensions: 574
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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